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Items: 1 to 20 of 59

1.

Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer.

Blick T, Hugo H, Widodo E, Waltham M, Pinto C, Mani SA, Weinberg RA, Neve RM, Lenburg ME, Thompson EW.

J Mammary Gland Biol Neoplasia. 2010 Jun;15(2):235-52. doi: 10.1007/s10911-010-9175-z. Epub 2010 Jun 4. Review.

PMID:
20521089
2.

DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation.

Eswaramoorthy R, Wang CK, Chen WC, Tang MJ, Ho ML, Hwang CC, Wang HM, Wang CZ.

J Cell Physiol. 2010 Aug;224(2):387-97. doi: 10.1002/jcp.22134.

PMID:
20432435
3.

SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer.

Sayan AE, Griffiths TR, Pal R, Browne GJ, Ruddick A, Yagci T, Edwards R, Mayer NJ, Qazi H, Goyal S, Fernandez S, Straatman K, Jones GD, Bowman KJ, Colquhoun A, Mellon JK, Kriajevska M, Tulchinsky E.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14884-9. doi: 10.1073/pnas.0902042106. Epub 2009 Aug 17.

4.

Identification of selective inhibitors of cancer stem cells by high-throughput screening.

Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES.

Cell. 2009 Aug 21;138(4):645-659. doi: 10.1016/j.cell.2009.06.034. Epub 2009 Aug 13.

5.

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features.

Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, Rimm DL, Wong H, Rodriguez A, Herschkowitz JI, Fan C, Zhang X, He X, Pavlick A, Gutierrez MC, Renshaw L, Larionov AA, Faratian D, Hilsenbeck SG, Perou CM, Lewis MT, Rosen JM, Chang JC.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13820-5. doi: 10.1073/pnas.0905718106. Epub 2009 Aug 3.

6.

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression.

Yu M, Smolen GA, Zhang J, Wittner B, Schott BJ, Brachtel E, Ramaswamy S, Maheswaran S, Haber DA.

Genes Dev. 2009 Aug 1;23(15):1737-42. doi: 10.1101/gad.1809309.

7.

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.

Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, Asselin-Labat ML, Gyorki DE, Ward T, Partanen A, Feleppa F, Huschtscha LI, Thorne HJ; kConFab, Fox SB, Yan M, French JD, Brown MA, Smyth GK, Visvader JE, Lindeman GJ.

Nat Med. 2009 Aug;15(8):907-13. doi: 10.1038/nm.2000. Epub 2009 Aug 2.

PMID:
19648928
8.

The basics of epithelial-mesenchymal transition.

Kalluri R, Weinberg RA.

J Clin Invest. 2009 Jun;119(6):1420-8. doi: 10.1172/JCI39104. Review. Erratum in: J Clin Invest. 2010 May 3;120(5):1786.

9.

DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading.

Wang CZ, Yeh YC, Tang MJ.

Am J Physiol Cell Physiol. 2009 Aug;297(2):C419-29. doi: 10.1152/ajpcell.00101.2009. Epub 2009 May 27.

10.

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

Hennessy BT, Gonzalez-Angulo AM, Stemke-Hale K, Gilcrease MZ, Krishnamurthy S, Lee JS, Fridlyand J, Sahin A, Agarwal R, Joy C, Liu W, Stivers D, Baggerly K, Carey M, Lluch A, Monteagudo C, He X, Weigman V, Fan C, Palazzo J, Hortobagyi GN, Nolden LK, Wang NJ, Valero V, Gray JW, Perou CM, Mills GB.

Cancer Res. 2009 May 15;69(10):4116-24. doi: 10.1158/0008-5472.CAN-08-3441. Epub 2009 May 12.

11.

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits.

Polyak K, Weinberg RA.

Nat Rev Cancer. 2009 Apr;9(4):265-73. doi: 10.1038/nrc2620. Epub 2009 Mar 5. Review.

PMID:
19262571
12.

A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer.

Farmer P, Bonnefoi H, Anderle P, Cameron D, Wirapati P, Becette V, André S, Piccart M, Campone M, Brain E, Macgrogan G, Petit T, Jassem J, Bibeau F, Blot E, Bogaerts J, Aguet M, Bergh J, Iggo R, Delorenzi M.

Nat Med. 2009 Jan;15(1):68-74. doi: 10.1038/nm.1908. Epub 2009 Jan 4. Erratum in: Nat Med. 2009 Feb;15(2):220. Wirapati, Pratyakasha [corrected to Wirapati, Pratyaksha].

PMID:
19122658
13.

MicroRNAs as regulators of epithelial-mesenchymal transition.

Gregory PA, Bracken CP, Bert AG, Goodall GJ.

Cell Cycle. 2008 Oct;7(20):3112-8. Epub 2008 Oct 25. Review.

PMID:
18927505
14.

Switching in discoid domain receptor expressions in SLUG-induced epithelial-mesenchymal transition.

Maeyama M, Koga H, Selvendiran K, Yanagimoto C, Hanada S, Taniguchi E, Kawaguchi T, Harada M, Ueno T, Sata M.

Cancer. 2008 Nov 15;113(10):2823-31. doi: 10.1002/cncr.23900.

15.

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition.

Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, Goodall GJ.

Cancer Res. 2008 Oct 1;68(19):7846-54. doi: 10.1158/0008-5472.CAN-08-1942.

16.

Cell type-specific DNA methylation patterns in the human breast.

Bloushtain-Qimron N, Yao J, Snyder EL, Shipitsin M, Campbell LL, Mani SA, Hu M, Chen H, Ustyansky V, Antosiewicz JE, Argani P, Halushka MK, Thomson JA, Pharoah P, Porgador A, Sukumar S, Parsons R, Richardson AL, Stampfer MR, Gelman RS, Nikolskaya T, Nikolsky Y, Polyak K.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14076-81. doi: 10.1073/pnas.0805206105. Epub 2008 Sep 9.

17.

Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers.

Sabbah M, Emami S, Redeuilh G, Julien S, Prévost G, Zimber A, Ouelaa R, Bracke M, De Wever O, Gespach C.

Drug Resist Updat. 2008 Aug-Oct;11(4-5):123-51. doi: 10.1016/j.drup.2008.07.001. Epub 2008 Aug 20. Review.

PMID:
18718806
18.

Generation of breast cancer stem cells through epithelial-mesenchymal transition.

Morel AP, Lièvre M, Thomas C, Hinkal G, Ansieau S, Puisieux A.

PLoS One. 2008 Aug 6;3(8):e2888. doi: 10.1371/journal.pone.0002888.

19.

Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models.

Vitali R, Mancini C, Cesi V, Tanno B, Mancuso M, Bossi G, Zhang Y, Martinez RV, Calabretta B, Dominici C, Raschellà G.

Clin Cancer Res. 2008 Jul 15;14(14):4622-30. doi: 10.1158/1078-0432.CCR-07-5210.

20.

The epithelial-mesenchymal transition generates cells with properties of stem cells.

Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA.

Cell. 2008 May 16;133(4):704-15. doi: 10.1016/j.cell.2008.03.027.

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