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Items: 1 to 20 of 40

1.

Novel function of CRTH2 in preventing apoptosis of human Th2 cells through activation of the phosphatidylinositol 3-kinase pathway.

Xue L, Barrow A, Pettipher R.

J Immunol. 2009 Jun 15;182(12):7580-6. doi: 10.4049/jimmunol.0804090.

2.

Increased expression of CRTH2 on eosinophils in allergic skin diseases.

Yahara H, Satoh T, Miyagishi C, Yokozeki H.

J Eur Acad Dermatol Venereol. 2010 Jan;24(1):75-6. doi: 10.1111/j.1468-3083.2009.03267.x. Epub 2009 Apr 8. No abstract available.

PMID:
19470039
3.

Genetic variation in CRTh2 influences development of allergic phenotypes.

Cameron L, Depner M, Kormann M, Klopp N, Illig T, von Mutius E, Kabesch M.

Allergy. 2009 Oct;64(10):1478-85. doi: 10.1111/j.1398-9995.2009.02053.x. Epub 2009 Apr 14.

4.

Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2).

Boehme SA, Franz-Bacon K, Chen EP, Ly TW, Kawakami Y, Bacon KB.

Int Immunol. 2009 Jun;21(6):621-32. doi: 10.1093/intimm/dxp031. Epub 2009 Apr 3.

PMID:
19346259
5.

Accumulation of CRTH2-positive leukocytes in human allergic nasal mucosa.

Shirasaki H, Kikuchi M, Kanaizumi E, Himi T.

Ann Allergy Asthma Immunol. 2009 Feb;102(2):110-5. doi: 10.1016/S1081-1206(10)60239-6.

PMID:
19230460
6.

Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms.

Boehme SA, Chen EP, Franz-Bacon K, Sásik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB.

Int Immunol. 2009 Jan;21(1):1-17. doi: 10.1093/intimm/dxn118. Epub 2008 Dec 9.

7.

Genetic variations in chemoattractant receptor expressed on Th2 cells (CRTH2) is associated with asthma susceptibility in Chinese children.

Wang J, Xu Y, Zhao H, Sui H, Liang H, Jiang X.

Mol Biol Rep. 2009 Jul;36(6):1549-53. doi: 10.1007/s11033-008-9349-6. Epub 2008 Sep 7.

PMID:
18777142
8.

CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation.

Lukacs NW, Berlin AA, Franz-Bacon K, Sásik R, Sprague LJ, Ly TW, Hardiman G, Boehme SA, Bacon KB.

Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L767-79. doi: 10.1152/ajplung.90351.2008. Epub 2008 Aug 29.

9.

Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation.

Shiraishi Y, Asano K, Niimi K, Fukunaga K, Wakaki M, Kagyo J, Takihara T, Ueda S, Nakajima T, Oguma T, Suzuki Y, Shiomi T, Sayama K, Kagawa S, Ikeda E, Hirai H, Nagata K, Nakamura M, Miyasho T, Ishizaka A.

J Immunol. 2008 Jan 1;180(1):541-9.

10.

The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking.

Schratl P, Royer JF, Kostenis E, Ulven T, Sturm EM, Waldhoer M, Hoefler G, Schuligoi R, Lippe IT, Peskar BA, Heinemann A.

J Immunol. 2007 Oct 1;179(7):4792-9.

12.

Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.

Uller L, Mathiesen JM, Alenmyr L, Korsgren M, Ulven T, Högberg T, Andersson G, Persson CG, Kostenis E.

Respir Res. 2007 Feb 28;8:16.

13.

Putative mechanism of the itch-scratch circle: repeated scratching decreases the cutaneous level of prostaglandin D2, a mediator that inhibits itching.

Sugimoto M, Arai I, Futaki N, Honma Y, Sakurai T, Hashimoto Y, Nakaike S.

Prostaglandins Leukot Essent Fatty Acids. 2007 Feb;76(2):93-101. Epub 2007 Jan 23.

PMID:
17250998
14.

Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor.

Satoh T, Moroi R, Aritake K, Urade Y, Kanai Y, Sumi K, Yokozeki H, Hirai H, Nagata K, Hara T, Utsuyama M, Hirokawa K, Sugamura K, Nishioka K, Nakamura M.

J Immunol. 2006 Aug 15;177(4):2621-9.

15.

Differential expression of genes involved in skin homing, proliferation, and apoptosis in CD4+ T cells of patients with atopic dermatitis.

Hijnen D, Nijhuis E, Bruin-Weller M, Holstege F, Koerkamp MG, Kok I, Bruijnzeel-Koomen C, Knol E.

J Invest Dermatol. 2005 Dec;125(6):1149-55.

16.
17.

COX-2 inhibition enhances the TH2 immune response to epicutaneous sensitization.

Laouini D, Elkhal A, Yalcindag A, Kawamoto S, Oettgen H, Geha RS.

J Allergy Clin Immunol. 2005 Aug;116(2):390-6.

PMID:
16083795
18.

Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment.

Chevalier E, Stock J, Fisher T, Dupont M, Fric M, Fargeau H, Leport M, Soler S, Fabien S, Pruniaux MP, Fink M, Bertrand CP, McNeish J, Li B.

J Immunol. 2005 Aug 15;175(4):2056-60.

19.

Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse.

Spik I, Brénuchon C, Angéli V, Staumont D, Fleury S, Capron M, Trottein F, Dombrowicz D.

J Immunol. 2005 Mar 15;174(6):3703-8.

20.

Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor.

Shiraishi Y, Asano K, Nakajima T, Oguma T, Suzuki Y, Shiomi T, Sayama K, Niimi K, Wakaki M, Kagyo J, Ikeda E, Hirai H, Yamaguchi K, Ishizaka A.

J Pharmacol Exp Ther. 2005 Mar;312(3):954-60. Epub 2004 Nov 4.

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