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Items: 1 to 20 of 29

1.

IL-7 enhances thymic human T cell development in "human immune system" Rag2-/-IL-2Rgammac-/- mice without affecting peripheral T cell homeostasis.

van Lent AU, Dontje W, Nagasawa M, Siamari R, Bakker AQ, Pouw SM, Maijoor KA, Weijer K, Cornelissen JJ, Blom B, Di Santo JP, Spits H, Legrand N.

J Immunol. 2009 Dec 15;183(12):7645-55. doi: 10.4049/jimmunol.0902019.

2.

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

Legrand N, Ploss A, Balling R, Becker PD, Borsotti C, Brezillon N, Debarry J, de Jong Y, Deng H, Di Santo JP, Eisenbarth S, Eynon E, Flavell RA, Guzman CA, Huntington ND, Kremsdorf D, Manns MP, Manz MG, Mention JJ, Ott M, Rathinam C, Rice CM, Rongvaux A, Stevens S, Spits H, Strick-Marchand H, Takizawa H, van Lent AU, Wang C, Weijer K, Willinger T, Ziegler P.

Cell Host Microbe. 2009 Jul 23;6(1):5-9. doi: 10.1016/j.chom.2009.06.006. Review.

3.

Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.

Pellegrini M, Calzascia T, Elford AR, Shahinian A, Lin AE, Dissanayake D, Dhanji S, Nguyen LT, Gronski MA, Morre M, Assouline B, Lahl K, Sparwasser T, Ohashi PS, Mak TW.

Nat Med. 2009 May;15(5):528-36. doi: 10.1038/nm.1953. Epub 2009 Apr 26. Erratum in: Nat Med. 2009 Jul;15(7):819.

PMID:
19396174
4.

IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.

Sereti I, Dunham RM, Spritzler J, Aga E, Proschan MA, Medvik K, Battaglia CA, Landay AL, Pahwa S, Fischl MA, Asmuth DM, Tenorio AR, Altman JD, Fox L, Moir S, Malaspina A, Morre M, Buffet R, Silvestri G, Lederman MM; ACTG 5214 Study Team.

Blood. 2009 Jun 18;113(25):6304-14. doi: 10.1182/blood-2008-10-186601. Epub 2009 Apr 20.

5.

Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment.

Levy Y, Lacabaratz C, Weiss L, Viard JP, Goujard C, Lelièvre JD, Boué F, Molina JM, Rouzioux C, Avettand-Fénoêl V, Croughs T, Beq S, Thiébaut R, Chêne G, Morre M, Delfraissy JF.

J Clin Invest. 2009 Apr;119(4):997-1007. doi: 10.1172/JCI38052. Epub 2009 Mar 16.

6.

Hepatic interleukin-7 expression regulates T cell responses.

Sawa Y, Arima Y, Ogura H, Kitabayashi C, Jiang JJ, Fukushima T, Kamimura D, Hirano T, Murakami M.

Immunity. 2009 Mar 20;30(3):447-57. doi: 10.1016/j.immuni.2009.01.007. Epub 2009 Mar 12.

7.

Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets.

Sportès C, Hakim FT, Memon SA, Zhang H, Chua KS, Brown MR, Fleisher TA, Krumlauf MC, Babb RR, Chow CK, Fry TJ, Engels J, Buffet R, Morre M, Amato RJ, Venzon DJ, Korngold R, Pecora A, Gress RE, Mackall CL.

J Exp Med. 2008 Jul 7;205(7):1701-14. doi: 10.1084/jem.20071681. Epub 2008 Jun 23.

8.

Engineered lentivector targeting of dendritic cells for in vivo immunization.

Yang L, Yang H, Rideout K, Cho T, Joo KI, Ziegler L, Elliot A, Walls A, Yu D, Baltimore D, Wang P.

Nat Biotechnol. 2008 Mar;26(3):326-34. doi: 10.1038/nbt1390. Epub 2008 Feb 24.

9.

Humanized mice in translational biomedical research.

Shultz LD, Ishikawa F, Greiner DL.

Nat Rev Immunol. 2007 Feb;7(2):118-30. Review.

PMID:
17259968
10.

HIV-1 infection and pathogenesis in a novel humanized mouse model.

Zhang L, Kovalev GI, Su L.

Blood. 2007 Apr 1;109(7):2978-81.

11.

Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

Melkus MW, Estes JD, Padgett-Thomas A, Gatlin J, Denton PW, Othieno FA, Wege AK, Haase AT, Garcia JV.

Nat Med. 2006 Nov;12(11):1316-22. Epub 2006 Oct 22.

PMID:
17057712
12.

Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice.

Baenziger S, Tussiwand R, Schlaepfer E, Mazzucchelli L, Heikenwalder M, Kurrer MO, Behnke S, Frey J, Oxenius A, Joller H, Aguzzi A, Manz MG, Speck RF.

Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15951-6. Epub 2006 Oct 12.

13.

Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis.

Ma A, Koka R, Burkett P.

Annu Rev Immunol. 2006;24:657-79. Review.

PMID:
16551262
14.
15.

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.

Ishikawa F, Yasukawa M, Lyons B, Yoshida S, Miyamoto T, Yoshimoto G, Watanabe T, Akashi K, Shultz LD, Harada M.

Blood. 2005 Sep 1;106(5):1565-73. Epub 2005 May 26.

16.

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.

Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R.

J Immunol. 2005 May 15;174(10):6477-89.

17.

Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells.

Gimeno R, Weijer K, Voordouw A, Uittenbogaart CH, Legrand N, Alves NL, Wijnands E, Blom B, Spits H.

Blood. 2004 Dec 15;104(13):3886-93. Epub 2004 Aug 19.

18.

Distinct regions of the interleukin-7 receptor regulate different Bcl2 family members.

Jiang Q, Li WQ, Hofmeister RR, Young HA, Hodge DR, Keller JR, Khaled AR, Durum SK.

Mol Cell Biol. 2004 Jul;24(14):6501-13.

19.

Development of a human adaptive immune system in cord blood cell-transplanted mice.

Traggiai E, Chicha L, Mazzucchelli L, Bronz L, Piffaretti JC, Lanzavecchia A, Manz MG.

Science. 2004 Apr 2;304(5667):104-7.

20.

Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors.

Follenzi A, Sabatino G, Lombardo A, Boccaccio C, Naldini L.

Hum Gene Ther. 2002 Jan 20;13(2):243-60.

PMID:
11812281

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