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Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study.

Tan ZS, Beiser AS, Fox CS, Au R, Himali JJ, Debette S, Decarli C, Vasan RS, Wolf PA, Seshadri S.

Diabetes Care. 2011 Aug;34(8):1766-70. doi: 10.2337/dc11-0308. Epub 2011 Jun 16.


Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging.

Lieb W, Beiser AS, Vasan RS, Tan ZS, Au R, Harris TB, Roubenoff R, Auerbach S, DeCarli C, Wolf PA, Seshadri S.

JAMA. 2009 Dec 16;302(23):2565-72. doi: 10.1001/jama.2009.1836.


Modifiers of cognitive function and brain structure in middle-aged and elderly individuals with type 2 diabetes mellitus.

Bruehl H, Wolf OT, Sweat V, Tirsi A, Richardson S, Convit A.

Brain Res. 2009 Jul 14;1280:186-94. doi: 10.1016/j.brainres.2009.05.032. Epub 2009 May 20.


Leptin: a novel therapeutic strategy for Alzheimer's disease.

Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S.

J Alzheimers Dis. 2009;16(4):731-40. doi: 10.3233/JAD-2009-1021. Review.


Total and regional adiposity and cognitive change in older adults: The Health, Aging and Body Composition (ABC) study.

Kanaya AM, Lindquist K, Harris TB, Launer L, Rosano C, Satterfield S, Yaffe K; Health ABC Study.

Arch Neurol. 2009 Mar;66(3):329-35. doi: 10.1001/archneurol.2008.570.


The role of fat topology in the risk of disease.

Matsuzawa Y.

Int J Obes (Lond). 2008 Dec;32 Suppl 7:S83-92. doi: 10.1038/ijo.2008.243. Review.


Relationship between plasma leptin level and brain structure in elderly: a voxel-based morphometric study.

Narita K, Kosaka H, Okazawa H, Murata T, Wada Y.

Biol Psychiatry. 2009 Jun 1;65(11):992-4. doi: 10.1016/j.biopsych.2008.10.006. Epub 2008 Nov 20.


Relationship between body mass index and brain volume in healthy adults.

Gunstad J, Paul RH, Cohen RA, Tate DF, Spitznagel MB, Grieve S, Gordon E.

Int J Neurosci. 2008 Nov;118(11):1582-93. doi: 10.1080/00207450701392282.


On the etiology of incident brain lacunes: longitudinal observations from the LADIS study.

Gouw AA, van der Flier WM, Pantoni L, Inzitari D, Erkinjuntti T, Wahlund LO, Waldemar G, Schmidt R, Fazekas F, Scheltens P, Barkhof F; LADIS study group.

Stroke. 2008 Nov;39(11):3083-5. doi: 10.1161/STROKEAHA.108.521807. Epub 2008 Aug 14.


Prevalence and correlates of silent cerebral infarcts in the Framingham offspring study.

Das RR, Seshadri S, Beiser AS, Kelly-Hayes M, Au R, Himali JJ, Kase CS, Benjamin EJ, Polak JF, O'Donnell CJ, Yoshita M, D'Agostino RB Sr, DeCarli C, Wolf PA.

Stroke. 2008 Nov;39(11):2929-35. doi: 10.1161/STROKEAHA.108.516575. Epub 2008 Jun 26.


Body mass index and magnetic resonance markers of brain integrity in adults.

Gazdzinski S, Kornak J, Weiner MW, Meyerhoff DJ.

Ann Neurol. 2008 May;63(5):652-7. doi: 10.1002/ana.21377.


Central obesity and increased risk of dementia more than three decades later.

Whitmer RA, Gustafson DR, Barrett-Connor E, Haan MN, Gunderson EP, Yaffe K.

Neurology. 2008 Sep 30;71(14):1057-64. doi: 10.1212/01.wnl.0000306313.89165.ef. Epub 2008 Mar 26.


Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study.

Pou KM, Massaro JM, Hoffmann U, Vasan RS, Maurovich-Horvat P, Larson MG, Keaney JF Jr, Meigs JB, Lipinska I, Kathiresan S, Murabito JM, O'Donnell CJ, Benjamin EJ, Fox CS.

Circulation. 2007 Sep 11;116(11):1234-41. Epub 2007 Aug 20.


Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study.

Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, Vasan RS, Murabito JM, Meigs JB, Cupples LA, D'Agostino RB Sr, O'Donnell CJ.

Circulation. 2007 Jul 3;116(1):39-48. Epub 2007 Jun 18.


Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study.

Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan RS, Larson MG, Meigs JB, Keaney JF Jr, Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C.

Neurology. 2007 Mar 27;68(13):1032-8.


Adipose tissue and atherosclerosis: exploring the connection.

Fantuzzi G, Mazzone T.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):996-1003. Epub 2007 Feb 15. Review.


The risk of dementia with increased body mass index.

Gorospe EC, Dave JK.

Age Ageing. 2007 Jan;36(1):23-9. Epub 2006 Nov 23. Review.


Comparison of anthropometric, area- and volume-based assessment of abdominal subcutaneous and visceral adipose tissue volumes using multi-detector computed tomography.

Maurovich-Horvat P, Massaro J, Fox CS, Moselewski F, O'Donnell CJ, Hoffmann U.

Int J Obes (Lond). 2007 Mar;31(3):500-6. Epub 2006 Sep 5.


Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies.

Romero-Corral A, Montori VM, Somers VK, Korinek J, Thomas RJ, Allison TG, Mookadam F, Lopez-Jimenez F.

Lancet. 2006 Aug 19;368(9536):666-78. Review.

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