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Items: 1 to 20 of 50

1.

Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver.

Cretenet G, Le Clech M, Gachon F.

Cell Metab. 2010 Jan;11(1):47-57. doi: 10.1016/j.cmet.2009.11.002.

2.

eIF2alpha kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver.

Dang Do AN, Kimball SR, Cavener DR, Jefferson LS.

Physiol Genomics. 2009 Aug 7;38(3):328-41. doi: 10.1152/physiolgenomics.90396.2008. Epub 2009 Jun 9.

3.

Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance.

Su Q, Tsai J, Xu E, Qiu W, Bereczki E, Santha M, Adeli K.

Hepatology. 2009 Jul;50(1):77-84. doi: 10.1002/hep.22960.

PMID:
19434737
4.

Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.

Thorp E, Li G, Seimon TA, Kuriakose G, Ron D, Tabas I.

Cell Metab. 2009 May;9(5):474-81. doi: 10.1016/j.cmet.2009.03.003.

5.

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.

Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F.

J Clin Invest. 2009 May;119(5):1201-15. doi: 10.1172/JCI37007. Epub 2009 Apr 13.

6.

Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis.

Pickens MK, Yan JS, Ng RK, Ogata H, Grenert JP, Beysen C, Turner SM, Maher JJ.

J Lipid Res. 2009 Oct;50(10):2072-82. doi: 10.1194/jlr.M900022-JLR200. Epub 2009 Mar 17.

7.

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

Rutkowski DT, Wu J, Back SH, Callaghan MU, Ferris SP, Iqbal J, Clark R, Miao H, Hassler JR, Fornek J, Katze MG, Hussain MM, Song B, Swathirajan J, Wang J, Yau GD, Kaufman RJ.

Dev Cell. 2008 Dec;15(6):829-40. doi: 10.1016/j.devcel.2008.10.015.

8.

Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.

Singh R, Wang Y, Xiang Y, Tanaka KE, Gaarde WA, Czaja MJ.

Hepatology. 2009 Jan;49(1):87-96. doi: 10.1002/hep.22578.

9.

The role of CHOP messenger RNA expression in the link between oxidative stress and apoptosis.

Ariyama Y, Tanaka Y, Shimizu H, Shimomura K, Okada S, Saito T, Yamada E, Oyadomari S, Mori M, Mori M.

Metabolism. 2008 Dec;57(12):1625-35. doi: 10.1016/j.metabol.2008.06.019.

PMID:
19013284
10.

Mechanisms of clofibrate-induced apoptosis in Yoshida AH-130 hepatoma cells.

Penna F, Reffo P, Muzio G, Canuto RA, Baccino FM, Bonelli G, Costelli P.

Biochem Pharmacol. 2009 Jan 15;77(2):169-76. doi: 10.1016/j.bcp.2008.10.004. Epub 2008 Oct 15.

PMID:
18983831
11.

PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.

Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, Romero M, Cavener DR, Thompson CB, Diehl JA.

Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16314-9. doi: 10.1073/pnas.0808517105. Epub 2008 Oct 13.

12.

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.

Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ.

J Clin Invest. 2008 Oct;118(10):3378-89. doi: 10.1172/JCI34587.

13.

Regulation of hepatic lipogenesis by the transcription factor XBP1.

Lee AH, Scapa EF, Cohen DE, Glimcher LH.

Science. 2008 Jun 13;320(5882):1492-6. doi: 10.1126/science.1158042.

14.

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice.

Oyadomari S, Harding HP, Zhang Y, Oyadomari M, Ron D.

Cell Metab. 2008 Jun;7(6):520-32. doi: 10.1016/j.cmet.2008.04.011.

15.

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet.

Rinella ME, Elias MS, Smolak RR, Fu T, Borensztajn J, Green RM.

J Lipid Res. 2008 May;49(5):1068-76. doi: 10.1194/jlr.M800042-JLR200. Epub 2008 Jan 28.

16.

Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease.

Puri P, Mirshahi F, Cheung O, Natarajan R, Maher JW, Kellum JM, Sanyal AJ.

Gastroenterology. 2008 Feb;134(2):568-76. Epub 2007 Oct 26.

PMID:
18082745
17.
18.

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1.

Yamamoto K, Sato T, Matsui T, Sato M, Okada T, Yoshida H, Harada A, Mori K.

Dev Cell. 2007 Sep;13(3):365-76.

19.

Chop-deficient mice showed increased adiposity but no glucose intolerance.

Ariyama Y, Shimizu H, Satoh T, Tsuchiya T, Okada S, Oyadomari S, Mori M, Mori M.

Obesity (Silver Spring). 2007 Jul;15(7):1647-56.

20.

Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.

Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV Sr, Hevener AL, Farese RV Jr.

Cell Metab. 2007 Jul;6(1):69-78.

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