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Items: 1 to 20 of 38

1.

Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements.

Letsolo BT, Rowson J, Baird DM.

Nucleic Acids Res. 2010 Apr;38(6):1841-52. doi: 10.1093/nar/gkp1183. Epub 2009 Dec 21.

2.

Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes.

Surovtseva YV, Churikov D, Boltz KA, Song X, Lamb JC, Warrington R, Leehy K, Heacock M, Price CM, Shippen DE.

Mol Cell. 2009 Oct 23;36(2):207-18. doi: 10.1016/j.molcel.2009.09.017.

3.

RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.

Miyake Y, Nakamura M, Nabetani A, Shimamura S, Tamura M, Yonehara S, Saito M, Ishikawa F.

Mol Cell. 2009 Oct 23;36(2):193-206. doi: 10.1016/j.molcel.2009.08.009.

4.

Altered states of telomere deprotection and the two-stage mechanism of replicative aging.

Zou Y, Misri S, Shay JW, Pandita TK, Wright WE.

Mol Cell Biol. 2009 May;29(9):2390-7. doi: 10.1128/MCB.01569-08. Epub 2009 Feb 17.

5.

Palindromic gene amplification--an evolutionarily conserved role for DNA inverted repeats in the genome.

Tanaka H, Yao MC.

Nat Rev Cancer. 2009 Mar;9(3):216-24. doi: 10.1038/nrc2591. Epub 2009 Feb 12. Review.

PMID:
19212324
6.

Chromosome fusions following telomere loss are mediated by single-strand annealing.

Wang X, Baumann P.

Mol Cell. 2008 Aug 22;31(4):463-73. doi: 10.1016/j.molcel.2008.05.028.

7.

How shelterin protects mammalian telomeres.

Palm W, de Lange T.

Annu Rev Genet. 2008;42:301-34. doi: 10.1146/annurev.genet.41.110306.130350. Review.

PMID:
18680434
8.

ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells.

Stohr BA, Blackburn EH.

Cancer Res. 2008 Jul 1;68(13):5309-17. doi: 10.1158/0008-5472.CAN-08-0504.

9.

The telomerase database.

Podlevsky JD, Bley CJ, Omana RV, Qi X, Chen JJ.

Nucleic Acids Res. 2008 Jan;36(Database issue):D339-43. Epub 2007 Dec 11.

10.
11.

The nature of telomere fusion and a definition of the critical telomere length in human cells.

Capper R, Britt-Compton B, Tankimanova M, Rowson J, Letsolo B, Man S, Haughton M, Baird DM.

Genes Dev. 2007 Oct 1;21(19):2495-508.

12.

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.

Denchi EL, de Lange T.

Nature. 2007 Aug 30;448(7157):1068-71. Epub 2007 Aug 8.

PMID:
17687332
13.

Replication fork stalling at natural impediments.

Mirkin EV, Mirkin SM.

Microbiol Mol Biol Rev. 2007 Mar;71(1):13-35. Review.

14.

Intrastrand annealing leads to the formation of a large DNA palindrome and determines the boundaries of genomic amplification in human cancer.

Tanaka H, Cao Y, Bergstrom DA, Kooperberg C, Tapscott SJ, Yao MC.

Mol Cell Biol. 2007 Mar;27(6):1993-2002. Epub 2007 Jan 22.

15.

Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements.

VanHulle K, Lemoine FJ, Narayanan V, Downing B, Hull K, McCullough C, Bellinger M, Lobachev K, Petes TD, Malkova A.

Mol Cell Biol. 2007 Apr;27(7):2601-14. Epub 2007 Jan 22.

16.

Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.

Hockemeyer D, Daniels JP, Takai H, de Lange T.

Cell. 2006 Jul 14;126(1):63-77.

17.

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.

Wu L, Multani AS, He H, Cosme-Blanco W, Deng Y, Deng JM, Bachilo O, Pathak S, Tahara H, Bailey SM, Deng Y, Behringer RR, Chang S.

Cell. 2006 Jul 14;126(1):49-62.

18.

Telomeres, chromosome instability and cancer.

Bailey SM, Murnane JP.

Nucleic Acids Res. 2006 May 8;34(8):2408-17. Print 2006. Review.

19.

Functional human telomeres are recognized as DNA damage in G2 of the cell cycle.

Verdun RE, Crabbe L, Haggblom C, Karlseder J.

Mol Cell. 2005 Nov 23;20(4):551-61.

20.

Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts.

MartĂ­n M, GenescĂ  A, Latre L, Jaco I, Taccioli GE, Egozcue J, Blasco MA, Iliakis G, Tusell L.

Cancer Res. 2005 Nov 15;65(22):10223-32.

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