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Items: 1 to 20 of 152


Changes in plasma membrane structure and electromotile properties in prestin deficient outer hair cells.

He DZ, Jia S, Sato T, Zuo J, Andrade LR, Riordan GP, Kachar B.

Cytoskeleton (Hoboken). 2010 Jan;67(1):43-55. doi: 10.1002/cm.20423.


The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins.

Yan J, Pan L, Chen X, Wu L, Zhang M.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4040-5. doi: 10.1073/pnas.0911385107. Epub 2010 Feb 8.


Twinfilin 2 regulates actin filament lengths in cochlear stereocilia.

Peng AW, Belyantseva IA, Hsu PD, Friedman TB, Heller S.

J Neurosci. 2009 Dec 2;29(48):15083-8. doi: 10.1523/JNEUROSCI.2782-09.2009.


Mechanotransduction by hair cells: models, molecules, and mechanisms.

Gillespie PG, Müller U.

Cell. 2009 Oct 2;139(1):33-44. doi: 10.1016/j.cell.2009.09.010. Review.


MyosinVIIa interacts with Twinfilin-2 at the tips of mechanosensory stereocilia in the inner ear.

Rzadzinska AK, Nevalainen EM, Prosser HM, Lappalainen P, Steel KP.

PLoS One. 2009 Sep 23;4(9):e7097. doi: 10.1371/journal.pone.0007097.


Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells.

Michalski N, Michel V, Caberlotto E, Lefèvre GM, van Aken AF, Tinevez JY, Bizard E, Houbron C, Weil D, Hardelin JP, Richardson GP, Kros CJ, Martin P, Petit C.

Pflugers Arch. 2009 Nov;459(1):115-30. doi: 10.1007/s00424-009-0711-x.


Development of form and function in the mammalian cochlea.

Kelly MC, Chen P.

Curr Opin Neurobiol. 2009 Aug;19(4):395-401. doi: 10.1016/j.conb.2009.07.010. Epub 2009 Aug 15. Review.


Line up and listen: Planar cell polarity regulation in the mammalian inner ear.

Rida PC, Chen P.

Semin Cell Dev Biol. 2009 Oct;20(8):978-85. doi: 10.1016/j.semcdb.2009.02.007. Review.


Gamma-actin is required for cytoskeletal maintenance but not development.

Belyantseva IA, Perrin BJ, Sonnemann KJ, Zhu M, Stepanyan R, McGee J, Frolenkov GI, Walsh EJ, Friderici KH, Friedman TB, Ervasti JM.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9703-8. doi: 10.1073/pnas.0900221106. Epub 2009 Jun 3.


Harmonin mutations cause mechanotransduction defects in cochlear hair cells.

Grillet N, Xiong W, Reynolds A, Kazmierczak P, Sato T, Lillo C, Dumont RA, Hintermann E, Sczaniecka A, Schwander M, Williams D, Kachar B, Gillespie PG, Müller U.

Neuron. 2009 May 14;62(3):375-87. doi: 10.1016/j.neuron.2009.04.006.


Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging.

Beurg M, Fettiplace R, Nam JH, Ricci AJ.

Nat Neurosci. 2009 May;12(5):553-8. doi: 10.1038/nn.2295. Epub 2009 Mar 29.


Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments.

Salles FT, Merritt RC Jr, Manor U, Dougherty GW, Sousa AD, Moore JE, Yengo CM, Dosé AC, Kachar B.

Nat Cell Biol. 2009 Apr;11(4):443-50. doi: 10.1038/ncb1851. Epub 2009 Mar 15.


Characterization of the Drosophila ortholog of the human Usher Syndrome type 1G protein sans.

Demontis F, Dahmann C.

PLoS One. 2009;4(3):e4753. doi: 10.1371/journal.pone.0004753. Epub 2009 Mar 9.


Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development.

Etheridge SL, Ray S, Li S, Hamblet NS, Lijam N, Tsang M, Greer J, Kardos N, Wang J, Sussman DJ, Chen P, Wynshaw-Boris A.

PLoS Genet. 2008 Nov;4(11):e1000259. doi: 10.1371/journal.pgen.1000259. Epub 2008 Nov 14.


Hair cell afferent synapses.

Glowatzki E, Grant L, Fuchs P.

Curr Opin Neurobiol. 2008 Aug;18(4):389-95. doi: 10.1016/j.conb.2008.09.006. Epub 2008 Oct 8. Review.


Making an effort to listen: mechanical amplification in the ear.

Hudspeth AJ.

Neuron. 2008 Aug 28;59(4):530-45. doi: 10.1016/j.neuron.2008.07.012. Review.


Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex.

Yamamoto S, Nishimura O, Misaki K, Nishita M, Minami Y, Yonemura S, Tarui H, Sasaki H.

Dev Cell. 2008 Jul;15(1):23-36. doi: 10.1016/j.devcel.2008.05.007.


The dimensions and composition of stereociliary rootlets in mammalian cochlear hair cells: comparison between high- and low-frequency cells and evidence for a connection to the lateral membrane.

Furness DN, Mahendrasingam S, Ohashi M, Fettiplace R, Hackney CM.

J Neurosci. 2008 Jun 18;28(25):6342-53. doi: 10.1523/JNEUROSCI.1154-08.2008.


Prestin-based outer hair cell motility is necessary for mammalian cochlear amplification.

Dallos P, Wu X, Cheatham MA, Gao J, Zheng J, Anderson CT, Jia S, Wang X, Cheng WH, Sengupta S, He DZ, Zuo J.

Neuron. 2008 May 8;58(3):333-9. doi: 10.1016/j.neuron.2008.02.028.


Dynamic compartmentalization of protein tyrosine phosphatase receptor Q at the proximal end of stereocilia: implication of myosin VI-based transport.

Sakaguchi H, Tokita J, Naoz M, Bowen-Pope D, Gov NS, Kachar B.

Cell Motil Cytoskeleton. 2008 Jul;65(7):528-38. doi: 10.1002/cm.20275.


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