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Items: 1 to 20 of 118

1.

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis.

Weidberg H, Shvets E, Shpilka T, Shimron F, Shinder V, Elazar Z.

EMBO J. 2010 Jun 2;29(11):1792-802. doi: 10.1038/emboj.2010.74. Epub 2010 Apr 23.

2.

Phosphoinositide signalling in cancer: beyond PI3K and PTEN.

Bunney TD, Katan M.

Nat Rev Cancer. 2010 May;10(5):342-52. doi: 10.1038/nrc2842. Review.

PMID:
20414202
3.

The mTOR pathway: a new target in cancer therapy.

Ciuffreda L, Di Sanza C, Incani UC, Milella M.

Curr Cancer Drug Targets. 2010 Aug;10(5):484-95. Review.

PMID:
20384580
4.

Gemcitabine induces the VMP1-mediated autophagy pathway to promote apoptotic death in human pancreatic cancer cells.

Pardo R, Lo Ré A, Archange C, Ropolo A, Papademetrio DL, Gonzalez CD, Alvarez EM, Iovanna JL, Vaccaro MI.

Pancreatology. 2010;10(1):19-26. doi: 10.1159/000264680. Epub 2010 Mar 19.

PMID:
20299819
5.

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells.

Ben Sahra I, Laurent K, Giuliano S, Larbret F, Ponzio G, Gounon P, Le Marchand-Brustel Y, Giorgetti-Peraldi S, Cormont M, Bertolotto C, Deckert M, Auberger P, Tanti JF, Bost F.

Cancer Res. 2010 Mar 15;70(6):2465-75. doi: 10.1158/0008-5472.CAN-09-2782. Epub 2010 Mar 9.

6.

Methods in mammalian autophagy research.

Mizushima N, Yoshimori T, Levine B.

Cell. 2010 Feb 5;140(3):313-26. doi: 10.1016/j.cell.2010.01.028.

7.

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG.

J Clin Invest. 2010 Jan;120(1):127-41. doi: 10.1172/JCI40027. Epub 2009 Dec 14.

8.

Autophagy and tumorigenesis.

Chen N, Debnath J.

FEBS Lett. 2010 Apr 2;584(7):1427-35. doi: 10.1016/j.febslet.2009.12.034. Epub 2009 Dec 24. Review.

9.

TOR-dependent control of autophagy: biting the hand that feeds.

Neufeld TP.

Curr Opin Cell Biol. 2010 Apr;22(2):157-68. doi: 10.1016/j.ceb.2009.11.005. Epub 2009 Dec 16. Review.

10.

mTOR and cancer: many loops in one pathway.

Efeyan A, Sabatini DM.

Curr Opin Cell Biol. 2010 Apr;22(2):169-76. doi: 10.1016/j.ceb.2009.10.007. Epub 2009 Nov 27.

11.

Autophagy inhibition in combination cancer treatment.

Livesey KM, Tang D, Zeh HJ, Lotze MT.

Curr Opin Investig Drugs. 2009 Dec;10(12):1269-79. Review.

PMID:
19943199
12.

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes.

Simonsen A, Tooze SA.

J Cell Biol. 2009 Sep 21;186(6):773-82. doi: 10.1083/jcb.200907014. Review.

13.

Tumour suppression by p53: a role for the DNA damage response?

Meek DW.

Nat Rev Cancer. 2009 Oct;9(10):714-23. doi: 10.1038/nrc2716. Epub 2009 Sep 4. Review.

PMID:
19730431
14.

Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine.

Shanmugam M, McBrayer SK, Qian J, Raikoff K, Avram MJ, Singhal S, Gandhi V, Schumacker PT, Krett NL, Rosen ST.

J Biol Chem. 2009 Sep 25;284(39):26816-30. doi: 10.1074/jbc.M109.000646. Epub 2009 Jul 31.

15.

Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells.

Tormo D, Checińska A, Alonso-Curbelo D, Pérez-Guijarro E, Cañón E, Riveiro-Falkenbach E, Calvo TG, Larribere L, Megías D, Mulero F, Piris MA, Dash R, Barral PM, Rodríguez-Peralto JL, Ortiz-Romero P, Tüting T, Fisher PB, Soengas MS.

Cancer Cell. 2009 Aug 4;16(2):103-14. doi: 10.1016/j.ccr.2009.07.004.

16.

Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab.

Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA.

PLoS One. 2009 Jul 16;4(7):e6251. doi: 10.1371/journal.pone.0006251.

17.

The prognostic role of Beclin 1 protein expression in high-grade gliomas.

Pirtoli L, Cevenini G, Tini P, Vannini M, Oliveri G, Marsili S, Mourmouras V, Rubino G, Miracco C.

Autophagy. 2009 Oct;5(7):930-6. Epub 2009 Oct 8.

PMID:
19556884
18.

Autophagy suppresses tumorigenesis through elimination of p62.

Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, Bray K, Reddy A, Bhanot G, Gelinas C, Dipaola RS, Karantza-Wadsworth V, White E.

Cell. 2009 Jun 12;137(6):1062-75. doi: 10.1016/j.cell.2009.03.048. Erratum in: Cell. 2011 Apr 15;145(2):322.

19.

p62 at the crossroads of autophagy, apoptosis, and cancer.

Moscat J, Diaz-Meco MT.

Cell. 2009 Jun 12;137(6):1001-4. doi: 10.1016/j.cell.2009.05.023. Review.

20.

Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.

Walker T, Mitchell C, Park MA, Yacoub A, Graf M, Rahmani M, Houghton PJ, Voelkel-Johnson C, Grant S, Dent P.

Mol Pharmacol. 2009 Aug;76(2):342-55. doi: 10.1124/mol.109.056523. Epub 2009 May 29.

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