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Items: 1 to 20 of 43


The nuts and bolts of AGC protein kinases.

Pearce LR, Komander D, Alessi DR.

Nat Rev Mol Cell Biol. 2010 Jan;11(1):9-22. doi: 10.1038/nrm2822. Review.


The Akt kinases: isoform specificity in metabolism and cancer.

Gonzalez E, McGraw TE.

Cell Cycle. 2009 Aug 15;8(16):2502-8. Epub 2009 Aug 23. Review.


3-D structure and dynamics of protein kinase B-new mechanism for the allosteric regulation of an AGC kinase.

Calleja V, Laguerre M, Larijani B.

J Chem Biol. 2009 Mar;2(1):11-25. doi: 10.1007/s12154-009-0016-8. Epub 2009 Feb 20.


Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition.

Calleja V, Laguerre M, Parker PJ, Larijani B.

PLoS Biol. 2009 Jan 20;7(1):e17. doi: 10.1371/journal.pbio.1000017.


Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling.

Ikenoue T, Inoki K, Yang Q, Zhou X, Guan KL.

EMBO J. 2008 Jul 23;27(14):1919-31. doi: 10.1038/emboj.2008.119. Epub 2008 Jun 19. Erratum in: EMBO J. 2008 Aug 20;27(16):2270.


The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.

Facchinetti V, Ouyang W, Wei H, Soto N, Lazorchak A, Gould C, Lowry C, Newton AC, Mao Y, Miao RQ, Sessa WC, Qin J, Zhang P, Su B, Jacinto E.

EMBO J. 2008 Jul 23;27(14):1932-43. doi: 10.1038/emboj.2008.120. Epub 2008 Jun 19.


AKT/PKB signaling: navigating downstream.

Manning BD, Cantley LC.

Cell. 2007 Jun 29;129(7):1261-74. Review.


Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation.

Hauge C, Antal TL, Hirschberg D, Doehn U, Thorup K, Idrissova L, Hansen K, Jensen ON, Jørgensen TJ, Biondi RM, Frödin M.

EMBO J. 2007 May 2;26(9):2251-61. Epub 2007 Apr 19.


Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo.

Calleja V, Alcor D, Laguerre M, Park J, Vojnovic B, Hemmings BA, Downward J, Parker PJ, Larijani B.

PLoS Biol. 2007 Apr;5(4):e95.


Insulin stimulates membrane fusion and GLUT4 accumulation in clathrin coats on adipocyte plasma membranes.

Huang S, Lifshitz LM, Jones C, Bellve KD, Standley C, Fonseca S, Corvera S, Fogarty KE, Czech MP.

Mol Cell Biol. 2007 May;27(9):3456-69. Epub 2007 Mar 5.


Structural determinants of LL5beta subcellular localisation and association with filamin C.

Paranavitane V, Stephens LR, Hawkins PT.

Cell Signal. 2007 Apr;19(4):817-24. Epub 2006 Dec 14.


CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta.

Lansbergen G, Grigoriev I, Mimori-Kiyosue Y, Ohtsuka T, Higa S, Kitajima I, Demmers J, Galjart N, Houtsmuller AB, Grosveld F, Akhmanova A.

Dev Cell. 2006 Jul;11(1):21-32.


Plasma membrane domains specialized for clathrin-mediated endocytosis in primary cells.

Bellve KD, Leonard D, Standley C, Lifshitz LM, Tuft RA, Hayakawa A, Corvera S, Fogarty KE.

J Biol Chem. 2006 Jun 9;281(23):16139-46. Epub 2006 Mar 13.


Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes.

Powelka AM, Seth A, Virbasius JV, Kiskinis E, Nicoloro SM, Guilherme A, Tang X, Straubhaar J, Cherniack AD, Parker MG, Czech MP.

J Clin Invest. 2006 Jan;116(1):125-36. Epub 2005 Dec 22.


Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells.

Lizunov VA, Matsumoto H, Zimmerberg J, Cushman SW, Frolov VA.

J Cell Biol. 2005 May 9;169(3):481-9. Epub 2005 May 2.


Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Sarbassov DD, Guertin DA, Ali SM, Sabatini DM.

Science. 2005 Feb 18;307(5712):1098-101.


Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.

Murray JT, Campbell DG, Peggie M, Mora A, Cohen P.

Biochem J. 2004 Dec 15;384(Pt 3):489-94. Erratum in: Biochem J. 2005 Feb 1;385(Pt 3):839. Alfonso, Mora [corrected to Mora, Alfonso].


A PCR primer bank for quantitative gene expression analysis.

Wang X, Seed B.

Nucleic Acids Res. 2003 Dec 15;31(24):e154.


Identification and characterization of human LL5A gene and mouse Ll5a gene in silico.

Katoh M, Katoh M.

Int J Oncol. 2003 Nov;23(5):1477-83.


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