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Items: 1 to 20 of 25


A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide.

Lee TK, Denny EM, Sanghvi JC, Gaston JE, Maynard ND, Hughey JJ, Covert MW.

Sci Signal. 2009 Oct 20;2(93):ra65. doi: 10.1126/scisignal.2000599.


Population context determines cell-to-cell variability in endocytosis and virus infection.

Snijder B, Sacher R, Rämö P, Damm EM, Liberali P, Pelkmans L.

Nature. 2009 Sep 24;461(7263):520-3. doi: 10.1038/nature08282. Epub 2009 Aug 26.


Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.

Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK.

Nature. 2009 May 21;459(7245):428-32. doi: 10.1038/nature08012. Epub 2009 Apr 12.


The ups and downs of p53: understanding protein dynamics in single cells.

Batchelor E, Loewer A, Lahav G.

Nat Rev Cancer. 2009 May;9(5):371-7. doi: 10.1038/nrc2604. Epub 2009 Apr 9. Review.


Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription.

Ashall L, Horton CA, Nelson DE, Paszek P, Harper CV, Sillitoe K, Ryan S, Spiller DG, Unitt JF, Broomhead DS, Kell DB, Rand DA, Sée V, White MR.

Science. 2009 Apr 10;324(5924):242-6. doi: 10.1126/science.1164860.


The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules.

Hao S, Baltimore D.

Nat Immunol. 2009 Mar;10(3):281-8. doi: 10.1038/ni.1699. Epub 2009 Feb 8.


Determination of cell fate selection during phage lambda infection.

St-Pierre F, Endy D.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20705-10. doi: 10.1073/pnas.0808831105. Epub 2008 Dec 19.


Dynamic proteomics of individual cancer cells in response to a drug.

Cohen AA, Geva-Zatorsky N, Eden E, Frenkel-Morgenstern M, Issaeva I, Sigal A, Milo R, Cohen-Saidon C, Liron Y, Kam Z, Cohen L, Danon T, Perzov N, Alon U.

Science. 2008 Dec 5;322(5907):1511-6. doi: 10.1126/science.1160165. Epub 2008 Nov 20.


Frequency-modulated nuclear localization bursts coordinate gene regulation.

Cai L, Dalal CK, Elowitz MB.

Nature. 2008 Sep 25;455(7212):485-90. doi: 10.1038/nature07292.


Encoding NF-kappaB temporal control in response to TNF: distinct roles for the negative regulators IkappaBalpha and A20.

Werner SL, Kearns JD, Zadorozhnaya V, Lynch C, O'Dea E, Boldin MP, Ma A, Baltimore D, Hoffmann A.

Genes Dev. 2008 Aug 1;22(15):2093-101. doi: 10.1101/gad.1680708.


Versatile, fully automated, microfluidic cell culture system.

Gómez-Sjöberg R, Leyrat AA, Pirone DM, Chen CS, Quake SR.

Anal Chem. 2007 Nov 15;79(22):8557-63. Epub 2007 Oct 23.


Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling.

Lipniacki T, Puszynski K, Paszek P, Brasier AR, Kimmel M.

BMC Bioinformatics. 2007 Oct 9;8:376.


IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway.

Hutti JE, Turk BE, Asara JM, Ma A, Cantley LC, Abbott DW.

Mol Cell Biol. 2007 Nov;27(21):7451-61. Epub 2007 Aug 20.


Mutations in the NF-kappaB signaling pathway: implications for human disease.

Courtois G, Gilmore TD.

Oncogene. 2006 Oct 30;25(51):6831-43. Review.


Circuitry of nuclear factor kappaB signaling.

Hoffmann A, Baltimore D.

Immunol Rev. 2006 Apr;210:171-86. Review.


Transient IkappaB kinase activity mediates temporal NF-kappaB dynamics in response to a wide range of tumor necrosis factor-alpha doses.

Cheong R, Bergmann A, Werner SL, Regal J, Hoffmann A, Levchenko A.

J Biol Chem. 2006 Feb 3;281(5):2945-50. Epub 2005 Dec 1.


Achieving stability of lipopolysaccharide-induced NF-kappaB activation.

Covert MW, Leung TH, Gaston JE, Baltimore D.

Science. 2005 Sep 16;309(5742):1854-7.


Oscillations in NF-kappaB signaling control the dynamics of gene expression.

Nelson DE, Ihekwaba AE, Elliott M, Johnson JR, Gibney CA, Foreman BE, Nelson G, See V, Horton CA, Spiller DG, Edwards SW, McDowell HP, Unitt JF, Sullivan E, Grimley R, Benson N, Broomhead D, Kell DB, White MR.

Science. 2004 Oct 22;306(5696):704-8.


Mathematical model of NF-kappaB regulatory module.

Lipniacki T, Paszek P, Brasier AR, Luxon B, Kimmel M.

J Theor Biol. 2004 May 21;228(2):195-215.


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