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Items: 1 to 20 of 57

1.

A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation.

Vergnolle N, Cenac N, Altier C, Cellars L, Chapman K, Zamponi GW, Materazzi S, Nassini R, Liedtke W, Cattaruzza F, Grady EF, Geppetti P, Bunnett NW.

Br J Pharmacol. 2010 Mar;159(5):1161-73. doi: 10.1111/j.1476-5381.2009.00590.x. Epub 2010 Feb 5.

2.

Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice.

Cattaruzza F, Spreadbury I, Miranda-Morales M, Grady EF, Vanner S, Bunnett NW.

Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G81-91. doi: 10.1152/ajpgi.00221.2009. Epub 2009 Oct 29.

3.

Cellular and molecular mechanisms of pain.

Basbaum AI, Bautista DM, Scherrer G, Julius D.

Cell. 2009 Oct 16;139(2):267-84. doi: 10.1016/j.cell.2009.09.028. Review.

4.

Protective effects and anti-inflammatory pathways of exogenous calcitonin gene-related peptide in severe necrotizing pancreatitis.

Schneider L, Hartwig W, Flemming T, Hackert T, Fortunato F, Heck M, Gebhard MM, Nawroth PP, Bierhaus A, Buchler MW, Werner J.

Pancreatology. 2009;9(5):662-9. doi: 10.1159/000212099. Epub 2009 Aug 14.

PMID:
19684430
5.

Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1.

Materazzi S, Nassini R, Andrè E, Campi B, Amadesi S, Trevisani M, Bunnett NW, Patacchini R, Geppetti P.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12045-50. doi: 10.1073/pnas.0802354105. Epub 2008 Aug 7.

6.

An improved method for extracting myeloperoxidase and determining its activity in the pancreas and lungs during pancreatitis.

Dawra R, Ku YS, Sharif R, Dhaulakhandi D, Phillips P, Dudeja V, Saluja AK.

Pancreas. 2008 Jul;37(1):62-8. doi: 10.1097/MPA.0b013e3181607761.

PMID:
18580446
7.

General anesthetics activate a nociceptive ion channel to enhance pain and inflammation.

Matta JA, Cornett PM, Miyares RL, Abe K, Sahibzada N, Ahern GP.

Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8784-9. doi: 10.1073/pnas.0711038105. Epub 2008 Jun 23.

8.

Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.

Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG, Poole DP, Bunnett NW, Geppetti P, Patacchini R.

J Clin Invest. 2008 Jul;118(7):2574-82. doi: 10.1172/JCI34886.

9.

Pain and chronic pancreatitis: is it the plumbing or the wiring?

Anaparthy R, Pasricha PJ.

Curr Gastroenterol Rep. 2008 Apr;10(2):101-6. Review.

PMID:
18462594
10.

Pharmacologic disruption of TRPV1-expressing primary sensory neurons but not genetic deletion of TRPV1 protects mice against pancreatitis.

Romac JM, McCall SJ, Humphrey JE, Heo J, Liddle RA.

Pancreas. 2008 May;36(4):394-401. doi: 10.1097/MPA.0b013e318160222a.

PMID:
18437086
11.

Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain.

Wang S, Dai Y, Fukuoka T, Yamanaka H, Kobayashi K, Obata K, Cui X, Tominaga M, Noguchi K.

Brain. 2008 May;131(Pt 5):1241-51. doi: 10.1093/brain/awn060. Epub 2008 Mar 20.

PMID:
18356188
12.

Selective role for TRPV4 ion channels in visceral sensory pathways.

Brierley SM, Page AJ, Hughes PA, Adam B, Liebregts T, Cooper NJ, Holtmann G, Liedtke W, Blackshaw LA.

Gastroenterology. 2008 Jun;134(7):2059-69. doi: 10.1053/j.gastro.2008.01.074. Epub 2008 Jan 31.

13.

Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.

Sipe WE, Brierley SM, Martin CM, Phillis BD, Cruz FB, Grady EF, Liedtke W, Cohen DM, Vanner S, Blackshaw LA, Bunnett NW.

Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1288-98. doi: 10.1152/ajpgi.00002.2008. Epub 2008 Mar 6.

14.

Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis.

Bhanot U, Köhntop R, Hasel C, Möller P.

J Pathol. 2008 Feb;214(3):312-9.

PMID:
18069660
15.

Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1).

Taylor-Clark TE, Undem BJ, Macglashan DW Jr, Ghatta S, Carr MJ, McAlexander MA.

Mol Pharmacol. 2008 Feb;73(2):274-81. Epub 2007 Nov 13.

16.

Transient receptor potential vanilloid 1 mediates hyperalgesia and is up-regulated in rats with chronic pancreatitis.

Xu GY, Winston JH, Shenoy M, Yin H, Pendyala S, Pasricha PJ.

Gastroenterology. 2007 Oct;133(4):1282-92. Epub 2007 Jun 20.

PMID:
17698068
17.

TRPA1 mediates formalin-induced pain.

McNamara CR, Mandel-Brehm J, Bautista DM, Siemens J, Deranian KL, Zhao M, Hayward NJ, Chong JA, Julius D, Moran MM, Fanger CM.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13525-30. Epub 2007 Aug 8.

18.

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.

Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R, Basbaum AI, Bunnett NW, Julius D, Geppetti P.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13519-24. Epub 2007 Aug 7.

19.

Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.

Knecht W, Cottrell GS, Amadesi S, Mohlin J, Skåregärde A, Gedda K, Peterson A, Chapman K, Hollenberg MD, Vergnolle N, Bunnett NW.

J Biol Chem. 2007 Sep 7;282(36):26089-100. Epub 2007 Jul 10.

20.

A mouse model of acute biliary pancreatitis induced by retrograde pancreatic duct infusion of Na-taurocholate.

Laukkarinen JM, Van Acker GJ, Weiss ER, Steer ML, Perides G.

Gut. 2007 Nov;56(11):1590-8. Epub 2007 Jun 25.

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