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Items: 1 to 20 of 34

1.

Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects.

Matsumoto Y, Matsumoto K, Irie F, Fukushi J, Stallcup WB, Yamaguchi Y.

J Biol Chem. 2010 Jun 18;285(25):19227-34. doi: 10.1074/jbc.M110.105338.

2.

Functional analysis of chick heparan sulfate 6-O-sulfotransferases in limb bud development.

Kobayashi T, Habuchi H, Nogami K, Ashikari-Hada S, Tamura K, Ide H, Kimata K.

Dev Growth Differ. 2010 Feb;52(2):146-56. doi: 10.1111/j.1440-169X.2009.01148.x.

PMID:
20039926
3.

Identification of a stem cell niche in the zone of Ranvier within the knee joint.

Karlsson C, Thornemo M, Henriksson HB, Lindahl A.

J Anat. 2009 Sep;215(3):355-63. doi: 10.1111/j.1469-7580.2009.01115.x.

4.

Heparan sulfate regulates ephrin-A3/EphA receptor signaling.

Irie F, Okuno M, Matsumoto K, Pasquale EB, Yamaguchi Y.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12307-12. doi: 10.1073/pnas.0801302105.

5.

Mechanical regulation of PTHrP expression in entheses.

Chen X, Macica C, Nasiri A, Judex S, Broadus AE.

Bone. 2007 Nov;41(5):752-9.

6.

The role of EXT1 in nonhereditary osteochondroma: identification of homozygous deletions.

Hameetman L, Szuhai K, Yavas A, Knijnenburg J, van Duin M, van Dekken H, Taminiau AH, Cleton-Jansen AM, Bovée JV, Hogendoorn PC.

J Natl Cancer Inst. 2007 Mar 7;99(5):396-406.

7.

Decreased EXT expression and intracellular accumulation of heparan sulphate proteoglycan in osteochondromas and peripheral chondrosarcomas.

Hameetman L, David G, Yavas A, White SJ, Taminiau AH, Cleton-Jansen AM, Hogendoorn PC, Bovée JV.

J Pathol. 2007 Mar;211(4):399-409.

PMID:
17226760
9.

Mice deficient in Ext2 lack heparan sulfate and develop exostoses.

Stickens D, Zak BM, Rougier N, Esko JD, Werb Z.

Development. 2005 Nov;132(22):5055-68.

10.

Manifestations of hereditary multiple exostoses.

Stieber JR, Dormans JP.

J Am Acad Orthop Surg. 2005 Mar-Apr;13(2):110-20. Review.

PMID:
15850368
11.

EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development.

Hilton MJ, Gutiérrez L, Martinez DA, Wells DE.

Bone. 2005 Mar;36(3):379-86.

PMID:
15777636
12.

Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton.

Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP.

Development. 2004 Mar;131(6):1309-18.

13.

Mammalian brain morphogenesis and midline axon guidance require heparan sulfate.

Inatani M, Irie F, Plump AS, Tessier-Lavigne M, Yamaguchi Y.

Science. 2003 Nov 7;302(5647):1044-6.

14.

Hereditary multiple exostoses and heparan sulfate polymerization.

Zak BM, Crawford BE, Esko JD.

Biochim Biophys Acta. 2002 Dec 19;1573(3):346-55. Review.

PMID:
12417417
15.

Reevaluation of a genetic model for the development of exostosis in hereditary multiple exostosis.

Hall CR, Cole WG, Haynes R, Hecht JT.

Am J Med Genet. 2002 Sep 15;112(1):1-5.

PMID:
12239711
16.

Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer.

Logan M, Martin JF, Nagy A, Lobe C, Olson EN, Tabin CJ.

Genesis. 2002 Jun;33(2):77-80.

PMID:
12112875
17.

Genotype-phenotype correlation in hereditary multiple exostoses.

Francannet C, Cohen-Tanugi A, Le Merrer M, Munnich A, Bonaventure J, Legeai-Mallet L.

J Med Genet. 2001 Jul;38(7):430-4.

18.

The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis.

Senay C, Lind T, Muguruma K, Tone Y, Kitagawa H, Sugahara K, Lidholt K, Lindahl U, Kusche-Gullberg M.

EMBO Rep. 2000 Sep;1(3):282-6.

19.

Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice.

Lin X, Wei G, Shi Z, Dryer L, Esko JD, Wells DE, Matzuk MM.

Dev Biol. 2000 Aug 15;224(2):299-311.

20.

Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function.

Tallquist MD, Soriano P.

Genesis. 2000 Feb;26(2):113-5. No abstract available.

PMID:
10686601
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