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Items: 1 to 20 of 53


Structural insights into RNA processing by the human RISC-loading complex.

Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E.

Nat Struct Mol Biol. 2009 Nov;16(11):1148-53. doi: 10.1038/nsmb.1673. Epub 2009 Oct 11.


A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.

Yeung ML, Houzet L, Yedavalli VS, Jeang KT.

J Biol Chem. 2009 Jul 17;284(29):19463-73. doi: 10.1074/jbc.M109.010033. Epub 2009 May 20.


MicroRNAs: target recognition and regulatory functions.

Bartel DP.

Cell. 2009 Jan 23;136(2):215-33. doi: 10.1016/j.cell.2009.01.002. Review.


HIV-1 Tat RNA silencing suppressor activity is conserved across kingdoms and counteracts translational repression of HIV-1.

Qian S, Zhong X, Yu L, Ding B, de Haan P, Boris-Lawrie K.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):605-10. doi: 10.1073/pnas.0806822106. Epub 2009 Jan 2.


How HTLV-1 may subvert miRNAs for persistence and transformation.

Bouzar AB, Willems L.

Retrovirology. 2008 Nov 12;5:101. doi: 10.1186/1742-4690-5-101. Review.


Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1.

Yeung ML, Yasunaga J, Bennasser Y, Dusetti N, Harris D, Ahmad N, Matsuoka M, Jeang KT.

Cancer Res. 2008 Nov 1;68(21):8976-85. doi: 10.1158/0008-5472.CAN-08-0769.


An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation.

Talotta F, Cimmino A, Matarazzo MR, Casalino L, De Vita G, D'Esposito M, Di Lauro R, Verde P.

Oncogene. 2009 Jan 8;28(1):73-84. doi: 10.1038/onc.2008.370. Epub 2008 Oct 13.


Mechanisms of microRNA deregulation in human cancer.

Deng S, Calin GA, Croce CM, Coukos G, Zhang L.

Cell Cycle. 2008 Sep 1;7(17):2643-6. Epub 2008 Sep 12. Review.


microRNAs and cancer: an overview.

Medina PP, Slack FJ.

Cell Cycle. 2008 Aug 15;7(16):2485-92. Epub 2008 Aug 17. Review.


Small-molecule inhibitors of microrna miR-21 function.

Gumireddy K, Young DD, Xiong X, Hogenesch JB, Huang Q, Deiters A.

Angew Chem Int Ed Engl. 2008;47(39):7482-4. doi: 10.1002/anie.200801555. No abstract available.


Human immunodeficiency virus type 1 replication and regulation of APOBEC3G by peptidyl prolyl isomerase Pin1.

Watashi K, Khan M, Yedavalli VR, Yeung ML, Strebel K, Jeang KT.

J Virol. 2008 Oct;82(20):9928-36. doi: 10.1128/JVI.01017-08. Epub 2008 Aug 6.


MicroRNAs: new regulators of immune cell development and function.

Baltimore D, Boldin MP, O'Connell RM, Rao DS, Taganov KD.

Nat Immunol. 2008 Aug;9(8):839-45. doi: 10.1038/ni.f.209. Review.


A small molecule enhances RNA interference and promotes microRNA processing.

Shan G, Li Y, Zhang J, Li W, Szulwach KE, Duan R, Faghihi MA, Khalil AM, Lu L, Paroo Z, Chan AW, Shi Z, Liu Q, Wahlestedt C, He C, Jin P.

Nat Biotechnol. 2008 Aug;26(8):933-40. doi: 10.1038/nbt.1481. Epub 2008 Jul 20.


MicroRNAs in diseases and drug response.

Garofalo M, Condorelli G, Croce CM.

Curr Opin Pharmacol. 2008 Oct;8(5):661-7. doi: 10.1016/j.coph.2008.06.005. Epub 2008 Jul 23. Review.


Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells.

Mudhasani R, Zhu Z, Hutvagner G, Eischen CM, Lyle S, Hall LL, Lawrence JB, Imbalzano AN, Jones SN.

J Cell Biol. 2008 Jun 30;181(7):1055-63. doi: 10.1083/jcb.200802105.


Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder.

O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, Nicoll J, Paquette RL, Baltimore D.

J Exp Med. 2008 Mar 17;205(3):585-94. doi: 10.1084/jem.20072108. Epub 2008 Feb 25.


MicroRNAs in disease and potential therapeutic applications.

Soifer HS, Rossi JJ, Saetrom P.

Mol Ther. 2007 Dec;15(12):2070-9. Epub 2007 Sep 18. Review.


Primer extension-based method for the generation of a siRNA/miRNA expression vector.

Gou D, Zhang H, Baviskar PS, Liu L.

Physiol Genomics. 2007 Nov 14;31(3):554-62. Epub 2007 Sep 5.

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