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Items: 1 to 20 of 34


Structural insight into the autoinhibition mechanism of AMP-activated protein kinase.

Chen L, Jiao ZH, Zheng LS, Zhang YY, Xie ST, Wang ZX, Wu JW.

Nature. 2009 Jun 25;459(7250):1146-9. doi: 10.1038/nature08075. Epub 2009 May 27.


Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

Scott JW, van Denderen BJ, Jorgensen SB, Honeyman JE, Steinberg GR, Oakhill JS, Iseli TJ, Koay A, Gooley PR, Stapleton D, Kemp BE.

Chem Biol. 2008 Nov 24;15(11):1220-30. doi: 10.1016/j.chembiol.2008.10.005.


Roles of the glycogen-binding domain and Snf4 in glucose inhibition of SNF1 protein kinase.

Momcilovic M, Iram SH, Liu Y, Carlson M.

J Biol Chem. 2008 Jul 11;283(28):19521-9. doi: 10.1074/jbc.M803624200. Epub 2008 May 12.


Structural insight into AMPK regulation: ADP comes into play.

Jin X, Townley R, Shapiro L.

Structure. 2007 Oct;15(10):1285-95.


Oligosaccharide recognition and binding to the carbohydrate binding module of AMP-activated protein kinase.

Koay A, Rimmer KA, Mertens HD, Gooley PR, Stapleton D.

FEBS Lett. 2007 Oct 30;581(26):5055-9. Epub 2007 Sep 29.


Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1.

Amodeo GA, Rudolph MJ, Tong L.

Nature. 2007 Sep 27;449(7161):492-5. Epub 2007 Sep 12.


Structural basis for AMP binding to mammalian AMP-activated protein kinase.

Xiao B, Heath R, Saiu P, Leiper FC, Leone P, Jing C, Walker PA, Haire L, Eccleston JF, Davis CT, Martin SR, Carling D, Gamblin SJ.

Nature. 2007 Sep 27;449(7161):496-500. Epub 2007 Sep 12.


AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy.

Hardie DG.

Nat Rev Mol Cell Biol. 2007 Oct;8(10):774-85. Review.


Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP.

Day P, Sharff A, Parra L, Cleasby A, Williams M, Hörer S, Nar H, Redemann N, Tickle I, Yon J.

Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):587-96. Epub 2007 Apr 21.


Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase.

Townley R, Shapiro L.

Science. 2007 Mar 23;315(5819):1726-9. Epub 2007 Feb 8.


Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.

Rudolph MJ, Amodeo GA, Iram SH, Hong SP, Pirino G, Carlson M, Tong L.

Structure. 2007 Jan;15(1):65-74.


Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits.

Pang T, Xiong B, Li JY, Qiu BY, Jin GZ, Shen JK, Li J.

J Biol Chem. 2007 Jan 5;282(1):495-506. Epub 2006 Nov 6.


Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family.

Nayak V, Zhao K, Wyce A, Schwartz MF, Lo WS, Berger SL, Marmorstein R.

Structure. 2006 Mar;14(3):477-85.


Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1.

Rudolph MJ, Amodeo GA, Bai Y, Tong L.

Biochem Biophys Res Commun. 2005 Dec 2;337(4):1224-8. Epub 2005 Oct 7.


Structural basis for glycogen recognition by AMP-activated protein kinase.

Polekhina G, Gupta A, van Denderen BJ, Feil SC, Kemp BE, Stapleton D, Parker MW.

Structure. 2005 Oct;13(10):1453-62.


AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.

Kahn BB, Alquier T, Carling D, Hardie DG.

Cell Metab. 2005 Jan;1(1):15-25. Review.


AMP-activated protein kinase beta subunit tethers alpha and gamma subunits via its C-terminal sequence (186-270).

Iseli TJ, Walter M, van Denderen BJ, Katsis F, Witters LA, Kemp BE, Michell BJ, Stapleton D.

J Biol Chem. 2005 Apr 8;280(14):13395-400. Epub 2005 Jan 28.


Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase.

Hedbacker K, Hong SP, Carlson M.

Mol Cell Biol. 2004 Sep;24(18):8255-63.


CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations.

Scott JW, Hawley SA, Green KA, Anis M, Stewart G, Scullion GA, Norman DG, Hardie DG.

J Clin Invest. 2004 Jan;113(2):274-84.


Bateman domains and adenosine derivatives form a binding contract.

Kemp BE.

J Clin Invest. 2004 Jan;113(2):182-4. Review.

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