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Items: 1 to 20 of 41

1.

The NF-kappaB-independent functions of IKK subunits in immunity and cancer.

Chariot A.

Trends Cell Biol. 2009 Aug;19(8):404-13. doi: 10.1016/j.tcb.2009.05.006. Epub 2009 Aug 3. Review.

PMID:
19648011
2.

Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

Compagno M, Lim WK, Grunn A, Nandula SV, Brahmachary M, Shen Q, Bertoni F, Ponzoni M, Scandurra M, Califano A, Bhagat G, Chadburn A, Dalla-Favera R, Pasqualucci L.

Nature. 2009 Jun 4;459(7247):717-21. doi: 10.1038/nature07968. Epub 2009 May 3.

3.

Frequent inactivation of A20 in B-cell lymphomas.

Kato M, Sanada M, Kato I, Sato Y, Takita J, Takeuchi K, Niwa A, Chen Y, Nakazaki K, Nomoto J, Asakura Y, Muto S, Tamura A, Iio M, Akatsuka Y, Hayashi Y, Mori H, Igarashi T, Kurokawa M, Chiba S, Mori S, Ishikawa Y, Okamoto K, Tobinai K, Nakagama H, Nakahata T, Yoshino T, Kobayashi Y, Ogawa S.

Nature. 2009 Jun 4;459(7247):712-6. doi: 10.1038/nature07969. Epub 2009 May 3.

PMID:
19412163
4.

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh WC, Mak TW, Korneluk RG, Cheng G.

Nat Immunol. 2008 Dec;9(12):1371-8. doi: 10.1038/ni.1676. Epub 2008 Nov 9.

5.

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.

Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, Wang H, Vignali DA, Bergsagel PL, Karin M.

Nat Immunol. 2008 Dec;9(12):1364-70. doi: 10.1038/ni.1678. Epub 2008 Nov 9.

6.

NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells.

Sasaki Y, Calado DP, Derudder E, Zhang B, Shimizu Y, Mackay F, Nishikawa S, Rajewsky K, Schmidt-Supprian M.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10883-8. doi: 10.1073/pnas.0805186105. Epub 2008 Jul 28.

7.

Ubiquitin-independent degradation of proteins by the proteasome.

Jariel-Encontre I, Bossis G, Piechaczyk M.

Biochim Biophys Acta. 2008 Dec;1786(2):153-77. doi: 10.1016/j.bbcan.2008.05.004. Epub 2008 Jun 17. Review.

PMID:
18558098
8.

TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.

Gardam S, Sierro F, Basten A, Mackay F, Brink R.

Immunity. 2008 Mar;28(3):391-401. doi: 10.1016/j.immuni.2008.01.009. Epub 2008 Feb 28.

9.

Control of canonical NF-kappaB activation through the NIK-IKK complex pathway.

Zarnegar B, Yamazaki S, He JQ, Cheng G.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3503-8. doi: 10.1073/pnas.0707959105. Epub 2008 Feb 21.

10.
11.

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ, Van Wier S, Tiedemann R, Shi CX, Sebag M, Braggio E, Henry T, Zhu YX, Fogle H, Price-Troska T, Ahmann G, Mancini C, Brents LA, Kumar S, Greipp P, Dispenzieri A, Bryant B, Mulligan G, Bruhn L, Barrett M, Valdez R, Trent J, Stewart AK, Carpten J, Bergsagel PL.

Cancer Cell. 2007 Aug;12(2):131-44.

12.

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.

Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F, Lenz G, Hanamura I, Wright G, Xiao W, Dave S, Hurt EM, Tan B, Zhao H, Stephens O, Santra M, Williams DR, Dang L, Barlogie B, Shaughnessy JD Jr, Kuehl WM, Staudt LM.

Cancer Cell. 2007 Aug;12(2):115-30.

13.

IKKalpha shields 14-3-3sigma, a G(2)/M cell cycle checkpoint gene, from hypermethylation, preventing its silencing.

Zhu F, Xia X, Liu B, Shen J, Hu Y, Person M, Hu Y.

Mol Cell. 2007 Jul 20;27(2):214-27.

14.

NF-kappaB and the immune response.

Hayden MS, West AP, Ghosh S.

Oncogene. 2006 Oct 30;25(51):6758-80. Review.

PMID:
17072327
15.

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription.

Scheidereit C.

Oncogene. 2006 Oct 30;25(51):6685-705. Review.

PMID:
17072322
16.

Rescue of TRAF3-null mice by p100 NF-kappa B deficiency.

He JQ, Zarnegar B, Oganesyan G, Saha SK, Yamazaki S, Doyle SE, Dempsey PW, Cheng G.

J Exp Med. 2006 Oct 30;203(11):2413-8. Epub 2006 Oct 2.

17.

Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease.

Enzler T, Bonizzi G, Silverman GJ, Otero DC, Widhopf GF, Anzelon-Mills A, Rickert RC, Karin M.

Immunity. 2006 Sep;25(3):403-15.

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20.

NF-(kappa)B-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis.

Aya K, Alhawagri M, Hagen-Stapleton A, Kitaura H, Kanagawa O, Novack DV.

J Clin Invest. 2005 Jul;115(7):1848-54. Epub 2005 Jun 2.

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