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Items: 1 to 20 of 80

1.

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.

2.

Activation of MDA5 requires higher-order RNA structures generated during virus infection.

Pichlmair A, Schulz O, Tan CP, Rehwinkel J, Kato H, Takeuchi O, Akira S, Way M, Schiavo G, Reis e Sousa C.

J Virol. 2009 Oct;83(20):10761-9. doi: 10.1128/JVI.00770-09. Epub 2009 Aug 5.

3.

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.

Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, Barchet W, Coch C, Janke M, Mihailovic A, Wardle G, Juranek S, Kato H, Kawai T, Poeck H, Fitzgerald KA, Takeuchi O, Akira S, Tuschl T, Latz E, Ludwig J, Hartmann G.

Immunity. 2009 Jul 17;31(1):25-34. doi: 10.1016/j.immuni.2009.05.008. Epub 2009 Jul 2.

4.

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I.

Schmidt A, Schwerd T, Hamm W, Hellmuth JC, Cui S, Wenzel M, Hoffmann FS, Michallet MC, Besch R, Hopfner KP, Endres S, Rothenfusser S.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12067-72. doi: 10.1073/pnas.0900971106. Epub 2009 Jul 2.

5.

Activation of Toll-like receptors inhibits herpes simplex virus-1 infection of human neuronal cells.

Zhou Y, Ye L, Wan Q, Zhou L, Wang X, Li J, Hu S, Zhou D, Ho W.

J Neurosci Res. 2009 Oct;87(13):2916-25. doi: 10.1002/jnr.22110.

6.

Pathogen recognition in the innate immune response.

Kumar H, Kawai T, Akira S.

Biochem J. 2009 Apr 28;420(1):1-16. doi: 10.1042/BJ20090272.

PMID:
19382893
7.

Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals.

Kroczynska B, Kaur S, Katsoulidis E, Majchrzak-Kita B, Sassano A, Kozma SC, Fish EN, Platanias LC.

Mol Cell Biol. 2009 May;29(10):2865-75. doi: 10.1128/MCB.01537-08. Epub 2009 Mar 16.

8.

Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies.

Ménager P, Roux P, Mégret F, Bourgeois JP, Le Sourd AM, Danckaert A, Lafage M, Préhaud C, Lafon M.

PLoS Pathog. 2009 Feb;5(2):e1000315. doi: 10.1371/journal.ppat.1000315. Epub 2009 Feb 27.

9.

Identification of thieno[3,2-b]pyrrole derivatives as novel small molecule inhibitors of neurotropic alphaviruses.

Peng W, Peltier DC, Larsen MJ, Kirchhoff PD, Larsen SD, Neubig RR, Miller DJ.

J Infect Dis. 2009 Apr 1;199(7):950-7. doi: 10.1086/597275.

10.

Variation matters: TLR structure and species-specific pathogen recognition.

Werling D, Jann OC, Offord V, Glass EJ, Coffey TJ.

Trends Immunol. 2009 Mar;30(3):124-30. doi: 10.1016/j.it.2008.12.001. Epub 2009 Feb 9. Review.

PMID:
19211304
11.

Local type I IFN receptor signaling protects against virus spread within the central nervous system.

Detje CN, Meyer T, Schmidt H, Kreuz D, Rose JK, Bechmann I, Prinz M, Kalinke U.

J Immunol. 2009 Feb 15;182(4):2297-304. doi: 10.4049/jimmunol.0800596.

12.

SHIP prevents lipopolysaccharide from triggering an antiviral response in mice.

Sly LM, Hamilton MJ, Kuroda E, Ho VW, Antignano FL, Omeis SL, van Netten-Thomas CJ, Wong D, Brugger HK, Williams O, Feldman ME, Houseman BT, Fiedler D, Shokat KM, Krystal G.

Blood. 2009 Mar 26;113(13):2945-54. doi: 10.1182/blood-2008-06-166082. Epub 2009 Jan 12.

13.

RNA recognition and signal transduction by RIG-I-like receptors.

Yoneyama M, Fujita T.

Immunol Rev. 2009 Jan;227(1):54-65. doi: 10.1111/j.1600-065X.2008.00727.x. Review.

PMID:
19120475
14.

Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.

Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP.

J Neurosci. 2008 Dec 17;28(51):13978-84. doi: 10.1523/JNEUROSCI.2140-08.2008.

15.

Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling.

Kaur S, Sassano A, Joseph AM, Majchrzak-Kita B, Eklund EA, Verma A, Brachmann SM, Fish EN, Platanias LC.

J Immunol. 2008 Nov 15;181(10):7316-23.

16.

Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway.

Cao W, Manicassamy S, Tang H, Kasturi SP, Pirani A, Murthy N, Pulendran B.

Nat Immunol. 2008 Oct;9(10):1157-64. doi: 10.1038/ni.1645. Epub 2008 Aug 31.

17.

Toll-like receptor 3 has a protective role against West Nile virus infection.

Daffis S, Samuel MA, Suthar MS, Gale M Jr, Diamond MS.

J Virol. 2008 Nov;82(21):10349-58. doi: 10.1128/JVI.00935-08. Epub 2008 Aug 20.

18.

Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling.

Kalali BN, Köllisch G, Mages J, Müller T, Bauer S, Wagner H, Ring J, Lang R, Mempel M, Ollert M.

J Immunol. 2008 Aug 15;181(4):2694-704.

19.

Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection.

Daffis S, Samuel MA, Suthar MS, Keller BC, Gale M Jr, Diamond MS.

J Virol. 2008 Sep;82(17):8465-75. doi: 10.1128/JVI.00918-08. Epub 2008 Jun 18.

20.

Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells.

Ohtani M, Nagai S, Kondo S, Mizuno S, Nakamura K, Tanabe M, Takeuchi T, Matsuda S, Koyasu S.

Blood. 2008 Aug 1;112(3):635-43. doi: 10.1182/blood-2008-02-137430. Epub 2008 May 20.

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