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Items: 1 to 20 of 35


Alterations in mitochondrial function as a harbinger of cardiomyopathy: lessons from the dystrophic heart.

Burelle Y, Khairallah M, Ascah A, Allen BG, Deschepper CF, Petrof BJ, Des Rosiers C.

J Mol Cell Cardiol. 2010 Feb;48(2):310-21. doi: 10.1016/j.yjmcc.2009.09.004. Epub 2009 Sep 18. Review.


Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition.

O'Shea KM, Khairallah RJ, Sparagna GC, Xu W, Hecker PA, Robillard-Frayne I, Des Rosiers C, Kristian T, Murphy RC, Fiskum G, Stanley WC.

J Mol Cell Cardiol. 2009 Dec;47(6):819-27. doi: 10.1016/j.yjmcc.2009.08.014. Epub 2009 Aug 22.


The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling.

Shah KB, Duda MK, O'Shea KM, Sparagna GC, Chess DJ, Khairallah RJ, Robillard-Frayne I, Xu W, Murphy RC, Des Rosiers C, Stanley WC.

Hypertension. 2009 Sep;54(3):605-11. doi: 10.1161/HYPERTENSIONAHA.109.135806. Epub 2009 Jul 13.


omega-3 polyunsaturated fatty acid supplementation for the treatment of heart failure: mechanisms and clinical potential.

Duda MK, O'Shea KM, Stanley WC.

Cardiovasc Res. 2009 Oct 1;84(1):33-41. doi: 10.1093/cvr/cvp169. Epub 2009 May 27. Review.


Cardiolipin remodeling in the heart.

Sparagna GC, Lesnefsky EJ.

J Cardiovasc Pharmacol. 2009 Apr;53(4):290-301. doi: 10.1097/FJC.0b013e31819b5461. Review.


What is the mitochondrial permeability transition pore?

Halestrap AP.

J Mol Cell Cardiol. 2009 Jun;46(6):821-31. doi: 10.1016/j.yjmcc.2009.02.021. Epub 2009 Mar 3. Review.


The mitochondrial permeability transition pore and ischemia-reperfusion injury.

Baines CP.

Basic Res Cardiol. 2009 Mar;104(2):181-8. doi: 10.1007/s00395-009-0004-8. Epub 2009 Feb 26. Review.


The molecular composition of the mitochondrial permeability transition pore.

Baines CP.

J Mol Cell Cardiol. 2009 Jun;46(6):850-7. doi: 10.1016/j.yjmcc.2009.02.007. Epub 2009 Feb 20. Review.


The role of the mitochondrial permeability transition pore in heart disease.

Halestrap AP, Pasdois P.

Biochim Biophys Acta. 2009 Nov;1787(11):1402-15. doi: 10.1016/j.bbabio.2008.12.017. Epub 2009 Jan 8. Review.


Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction.

Duda MK, O'Shea KM, Tintinu A, Xu W, Khairallah RJ, Barrows BR, Chess DJ, Azimzadeh AM, Harris WS, Sharov VG, Sabbah HN, Stanley WC.

Cardiovasc Res. 2009 Feb 1;81(2):319-27. doi: 10.1093/cvr/cvn310. Epub 2008 Nov 17.


Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial.

Tavazzi L, Maggioni AP, Marchioli R, Barlera S, Franzosi MG, Latini R, Lucci D, Nicolosi GL, Porcu M, Tognoni G; Gissi-HF Investigators.

Lancet. 2008 Oct 4;372(9645):1223-30. doi: 10.1016/S0140-6736(08)61239-8. Epub 2008 Aug 29.


Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation.

Basso E, Petronilli V, Forte MA, Bernardi P.

J Biol Chem. 2008 Sep 26;283(39):26307-11. doi: 10.1074/jbc.C800132200. Epub 2008 Aug 6.


Rat heart cannot synthesize docosahexaenoic acid from circulating alpha-linolenic acid because it lacks elongase-2.

Igarashi M, Ma K, Chang L, Bell JM, Rapoport SI.

J Lipid Res. 2008 Aug;49(8):1735-45. doi: 10.1194/jlr.M800093-JLR200. Epub 2008 May 1.


Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure.

Nakayama H, Chen X, Baines CP, Klevitsky R, Zhang X, Zhang H, Jaleel N, Chua BH, Hewett TE, Robbins J, Houser SR, Molkentin JD.

J Clin Invest. 2007 Sep;117(9):2431-44.


Role of Ca2+-independent phospholipase A2gamma in Ca2+-induced mitochondrial permeability transition.

Kinsey GR, McHowat J, Patrick KS, Schnellmann RG.

J Pharmacol Exp Ther. 2007 May;321(2):707-15. Epub 2007 Feb 20.


The independent effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors in humans.

Mori TA, Woodman RJ.

Curr Opin Clin Nutr Metab Care. 2006 Mar;9(2):95-104. Review.


Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death.

Baines CP, Kaiser RA, Purcell NH, Blair NS, Osinska H, Hambleton MA, Brunskill EW, Sayen MR, Gottlieb RA, Dorn GW, Robbins J, Molkentin JD.

Nature. 2005 Mar 31;434(7033):658-62.


Quantitation of cardiolipin molecular species in spontaneously hypertensive heart failure rats using electrospray ionization mass spectrometry.

Sparagna GC, Johnson CA, McCune SA, Moore RL, Murphy RC.

J Lipid Res. 2005 Jun;46(6):1196-204. Epub 2005 Mar 16.

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