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Items: 1 to 20 of 47


Mitochondrial membrane permeabilization in neuronal injury.

Galluzzi L, Blomgren K, Kroemer G.

Nat Rev Neurosci. 2009 Jul;10(7):481-94. doi: 10.1038/nrn2665. Review.


Mitochondrial outer-membrane permeabilization and remodelling in apoptosis.

Jourdain A, Martinou JC.

Int J Biochem Cell Biol. 2009 Oct;41(10):1884-9. doi: 10.1016/j.biocel.2009.05.001. Epub 2009 May 9. Review.


Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis.

Magrané J, Manfredi G.

Antioxid Redox Signal. 2009 Jul;11(7):1615-26. doi: 10.1089/ARS.2009.2604. Review.


Axonal mitochondrial clusters containing mutant SOD1 in transgenic models of ALS.

Sotelo-Silveira JR, Lepanto P, Elizondo V, Horjales S, Palacios F, Martinez-Palma L, Marin M, Beckman JS, Barbeito L.

Antioxid Redox Signal. 2009 Jul;11(7):1535-45. doi: 10.1089/ARS.2009.2614.


Molecular participants in mitochondrial cell death channel formation during neuronal ischemia.

Jonas EA.

Exp Neurol. 2009 Aug;218(2):203-12. doi: 10.1016/j.expneurol.2009.03.025. Epub 2009 Mar 31. Review.


The mitochondrial death pathway: a promising therapeutic target in diseases.

Gupta S, Kass GE, Szegezdi E, Joseph B.

J Cell Mol Med. 2009 Jun;13(6):1004-33. doi: 10.1111/j.1582-4934.2009.00697.x. Epub 2009 Feb 9. Review.


The Psi(m) depolarization that accompanies mitochondrial Ca2+ uptake is greater in mutant SOD1 than in wild-type mouse motor terminals.

Nguyen KT, García-Chacón LE, Barrett JN, Barrett EF, David G.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):2007-11. doi: 10.1073/pnas.0810934106. Epub 2009 Jan 27.


Bcl-2 family proteins as regulators of oxidative stress.

Susnow N, Zeng L, Margineantu D, Hockenbery DM.

Semin Cancer Biol. 2009 Feb;19(1):42-9. doi: 10.1016/j.semcancer.2008.12.002. Epub 2008 Dec 24. Review.


Recruitment of mitochondria into apoptotic signaling correlates with the presence of inclusions formed by amyotrophic lateral sclerosis-associated SOD1 mutations.

Soo KY, Atkin JD, Horne MK, Nagley P.

J Neurochem. 2009 Feb;108(3):578-90. doi: 10.1111/j.1471-4159.2008.05799.x. Epub 2008 Nov 27.


A short Nur77-derived peptide converts Bcl-2 from a protector to a killer.

Kolluri SK, Zhu X, Zhou X, Lin B, Chen Y, Sun K, Tian X, Town J, Cao X, Lin F, Zhai D, Kitada S, Luciano F, O'Donnell E, Cao Y, He F, Lin J, Reed JC, Satterthwait AC, Zhang XK.

Cancer Cell. 2008 Oct 7;14(4):285-98. doi: 10.1016/j.ccr.2008.09.002.


Lysyl-tRNA synthetase is a target for mutant SOD1 toxicity in mitochondria.

Kawamata H, Magrané J, Kunst C, King MP, Manfredi G.

J Biol Chem. 2008 Oct 17;283(42):28321-8. doi: 10.1074/jbc.M805599200. Epub 2008 Aug 20.


Amyotrophic lateral sclerosis: from current developments in the laboratory to clinical implications.

Cozzolino M, Ferri A, Carrì MT.

Antioxid Redox Signal. 2008 Mar;10(3):405-43. doi: 10.1089/ars.2007.1760. Review.


Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria.

Vande Velde C, Miller TM, Cashman NR, Cleveland DW.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):4022-7. doi: 10.1073/pnas.0712209105. Epub 2008 Feb 22.


Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria.

Zimmermann AK, Loucks FA, Schroeder EK, Bouchard RJ, Tyler KL, Linseman DA.

J Biol Chem. 2007 Oct 5;282(40):29296-304. Epub 2007 Aug 9.


Mitochondrial membrane permeabilization in cell death.

Kroemer G, Galluzzi L, Brenner C.

Physiol Rev. 2007 Jan;87(1):99-163. Review.


Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2.

Lei X, Chen Y, Du G, Yu W, Wang X, Qu H, Xia B, He H, Mao J, Zong W, Liao X, Mehrpour M, Hao X, Chen Q.

FASEB J. 2006 Oct;20(12):2147-9. Epub 2006 Aug 25.


Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS.

Gould TW, Buss RR, Vinsant S, Prevette D, Sun W, Knudson CM, Milligan CE, Oppenheim RW.

J Neurosci. 2006 Aug 23;26(34):8774-86.


Molecular biology of amyotrophic lateral sclerosis: insights from genetics.

Pasinelli P, Brown RH.

Nat Rev Neurosci. 2006 Sep;7(9):710-23. Review.


p53 and Nur77/TR3 - transcription factors that directly target mitochondria for cell death induction.

Moll UM, Marchenko N, Zhang XK.

Oncogene. 2006 Aug 7;25(34):4725-43. Review.


Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice.

Damiano M, Starkov AA, Petri S, Kipiani K, Kiaei M, Mattiazzi M, Flint Beal M, Manfredi G.

J Neurochem. 2006 Mar;96(5):1349-61.

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