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Items: 1 to 20 of 131

1.

The WW domain protein Kibra acts upstream of Hippo in Drosophila.

Baumgartner R, Poernbacher I, Buser N, Hafen E, Stocker H.

Dev Cell. 2010 Feb 16;18(2):309-16. doi: 10.1016/j.devcel.2009.12.013.

2.

Kibra is a regulator of the Salvador/Warts/Hippo signaling network.

Genevet A, Wehr MC, Brain R, Thompson BJ, Tapon N.

Dev Cell. 2010 Feb 16;18(2):300-8. doi: 10.1016/j.devcel.2009.12.011.

3.

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

Yu J, Zheng Y, Dong J, Klusza S, Deng WM, Pan D.

Dev Cell. 2010 Feb 16;18(2):288-99. doi: 10.1016/j.devcel.2009.12.012.

4.

Structural basis of YAP recognition by TEAD4 in the hippo pathway.

Chen L, Chan SW, Zhang X, Walsh M, Lim CJ, Hong W, Song H.

Genes Dev. 2010 Feb 1;24(3):290-300. doi: 10.1101/gad.1865310.

5.

Structural insights into the YAP and TEAD complex.

Li Z, Zhao B, Wang P, Chen F, Dong Z, Yang H, Guan KL, Xu Y.

Genes Dev. 2010 Feb 1;24(3):235-40. doi: 10.1101/gad.1865810.

6.

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver.

Lu L, Li Y, Kim SM, Bossuyt W, Liu P, Qiu Q, Wang Y, Halder G, Finegold MJ, Lee JS, Johnson RL.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1437-42. doi: 10.1073/pnas.0911427107. Epub 2010 Jan 4.

7.

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression.

Song H, Mak KK, Topol L, Yun K, Hu J, Garrett L, Chen Y, Park O, Chang J, Simpson RM, Wang CY, Gao B, Jiang J, Yang Y.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1431-6. doi: 10.1073/pnas.0911409107. Epub 2010 Jan 8.

8.

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).

Zhao B, Li L, Tumaneng K, Wang CY, Guan KL.

Genes Dev. 2010 Jan 1;24(1):72-85. doi: 10.1101/gad.1843810.

9.

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation.

Fernandez-L A, Northcott PA, Dalton J, Fraga C, Ellison D, Angers S, Taylor MD, Kenney AM.

Genes Dev. 2009 Dec 1;23(23):2729-41. doi: 10.1101/gad.1824509.

10.

miR-372 regulates cell cycle and apoptosis of ags human gastric cancer cell line through direct regulation of LATS2.

Cho WJ, Shin JM, Kim JS, Lee MR, Hong KS, Lee JH, Koo KH, Park JW, Kim KS.

Mol Cells. 2009 Dec 31;28(6):521-7. doi: 10.1007/s10059-009-0158-0. Epub 2009 Nov 19.

11.

YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway.

Zhang J, Ji JY, Yu M, Overholtzer M, Smolen GA, Wang R, Brugge JS, Dyson NJ, Haber DA.

Nat Cell Biol. 2009 Dec;11(12):1444-50. doi: 10.1038/ncb1993. Epub 2009 Nov 22.

12.

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.

Alarcón C, Zaromytidou AI, Xi Q, Gao S, Yu J, Fujisawa S, Barlas A, Miller AN, Manova-Todorova K, Macias MJ, Sapkota G, Pan D, Massagué J.

Cell. 2009 Nov 13;139(4):757-69. doi: 10.1016/j.cell.2009.09.035.

13.

Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila.

Ho LL, Wei X, Shimizu T, Lai ZC.

Dev Biol. 2010 Jan 15;337(2):274-83. doi: 10.1016/j.ydbio.2009.10.042. Epub 2009 Nov 12.

14.

Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms.

Ren F, Zhang L, Jiang J.

Dev Biol. 2010 Jan 15;337(2):303-12. doi: 10.1016/j.ydbio.2009.10.046. Epub 2009 Nov 6.

15.

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene.

Zhou D, Conrad C, Xia F, Park JS, Payer B, Yin Y, Lauwers GY, Thasler W, Lee JT, Avruch J, Bardeesy N.

Cancer Cell. 2009 Nov 6;16(5):425-38. doi: 10.1016/j.ccr.2009.09.026.

16.

MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability.

Densham RM, O'Neill E, Munro J, König I, Anderson K, Kolch W, Olson MF.

Mol Cell Biol. 2009 Dec;29(24):6380-90. doi: 10.1128/MCB.00116-09. Epub 2009 Oct 12.

17.

Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.

Oh S, Lee D, Kim T, Kim TS, Oh HJ, Hwang CY, Kong YY, Kwon KS, Lim DS.

Mol Cell Biol. 2009 Dec;29(23):6309-20. doi: 10.1128/MCB.00551-09. Epub 2009 Sep 28.

18.
19.

Molecular characterization of human homologs of yeast MOB1.

Chow A, Hao Y, Yang X.

Int J Cancer. 2010 May 1;126(9):2079-89. doi: 10.1002/ijc.24878.

20.

Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.

Oh H, Reddy BV, Irvine KD.

Dev Biol. 2009 Nov 1;335(1):188-97. doi: 10.1016/j.ydbio.2009.08.026. Epub 2009 Sep 3.

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