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Items: 1 to 20 of 48

1.

Alzheimer's disease and the amyloid-beta peptide.

Murphy MP, LeVine H 3rd.

J Alzheimers Dis. 2010;19(1):311-23. doi: 10.3233/JAD-2010-1221. Review.

2.

Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.

Kim M, Suh J, Romano D, Truong MH, Mullin K, Hooli B, Norton D, Tesco G, Elliott K, Wagner SL, Moir RD, Becker KD, Tanzi RE.

Hum Mol Genet. 2009 Oct 15;18(20):3987-96. doi: 10.1093/hmg/ddp323. Epub 2009 Jul 15.

3.

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease.

Roher AE, Esh CL, Kokjohn TA, Castaño EM, Van Vickle GD, Kalback WM, Patton RL, Luehrs DC, Daugs ID, Kuo YM, Emmerling MR, Soares H, Quinn JF, Kaye J, Connor DJ, Silverberg NB, Adler CH, Seward JD, Beach TG, Sabbagh MN.

Alzheimers Dement. 2009 Jan;5(1):18-29. doi: 10.1016/j.jalz.2008.10.004.

4.

The canine (dog) model of human aging and disease: dietary, environmental and immunotherapy approaches.

Cotman CW, Head E.

J Alzheimers Dis. 2008 Dec;15(4):685-707. Review.

PMID:
19096165
5.

Rate of entorhinal and hippocampal atrophy in incipient and mild AD: relation to memory function.

Stoub TR, Rogalski EJ, Leurgans S, Bennett DA, deToledo-Morrell L.

Neurobiol Aging. 2010 Jul;31(7):1089-98. doi: 10.1016/j.neurobiolaging.2008.08.003. Epub 2008 Sep 21.

6.

Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks.

Kuchibhotla KV, Goldman ST, Lattarulo CR, Wu HY, Hyman BT, Bacskai BJ.

Neuron. 2008 Jul 31;59(2):214-25. doi: 10.1016/j.neuron.2008.06.008.

7.

Amyloid precursor protein trafficking, processing, and function.

Thinakaran G, Koo EH.

J Biol Chem. 2008 Oct 31;283(44):29615-9. doi: 10.1074/jbc.R800019200. Epub 2008 Jul 23. Review.

8.
9.

Distinct pools of beta-amyloid in Alzheimer disease-affected brain: a clinicopathologic study.

Steinerman JR, Irizarry M, Scarmeas N, Raju S, Brandt J, Albert M, Blacker D, Hyman B, Stern Y.

Arch Neurol. 2008 Jul;65(7):906-12. doi: 10.1001/archneur.65.7.906.

10.

A two-year study with fibrillar beta-amyloid (Abeta) immunization in aged canines: effects on cognitive function and brain Abeta.

Head E, Pop V, Vasilevko V, Hill M, Saing T, Sarsoza F, Nistor M, Christie LA, Milton S, Glabe C, Barrett E, Cribbs D.

J Neurosci. 2008 Apr 2;28(14):3555-66. doi: 10.1523/JNEUROSCI.0208-08.2008.

11.

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior.

Selkoe DJ.

Behav Brain Res. 2008 Sep 1;192(1):106-13. doi: 10.1016/j.bbr.2008.02.016. Epub 2008 Feb 17. Review.

12.

Plaque-bearing mice with reduced levels of oligomeric amyloid-beta assemblies have intact memory function.

Lesné S, Kotilinek L, Ashe KH.

Neuroscience. 2008 Feb 6;151(3):745-9. Epub 2007 Nov 17.

13.

Implications of age and diet on canine cerebral cortex transcription.

Swanson KS, Vester BM, Apanavicius CJ, Kirby NA, Schook LB.

Neurobiol Aging. 2009 Aug;30(8):1314-26. Epub 2008 Feb 20.

PMID:
18079023
14.

Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice.

Murphy MP, Beckett TL, Ding Q, Patel E, Markesbery WR, St Clair DK, LeVine H 3rd, Keller JN.

Neurobiol Dis. 2007 Sep;27(3):301-11. Epub 2007 Jun 12.

PMID:
17651976
15.

Brain structural alterations before mild cognitive impairment.

Smith CD, Chebrolu H, Wekstein DR, Schmitt FA, Jicha GA, Cooper G, Markesbery WR.

Neurology. 2007 Apr 17;68(16):1268-73.

PMID:
17438217
16.

Qualitative estimates of medial temporal atrophy as a predictor of progression from mild cognitive impairment to dementia.

DeCarli C, Frisoni GB, Clark CM, Harvey D, Grundman M, Petersen RC, Thal LJ, Jin S, Jack CR Jr, Scheltens P; Alzheimer's Disease Cooperative Study Group..

Arch Neurol. 2007 Jan;64(1):108-15. Erratum in: Arch Neurol. 2007 Mar;64(3):459.

PMID:
17210817
17.

Monoclonal antibodies that target pathological assemblies of Abeta.

Lambert MP, Velasco PT, Chang L, Viola KL, Fernandez S, Lacor PN, Khuon D, Gong Y, Bigio EH, Shaw P, De Felice FG, Krafft GA, Klein WL.

J Neurochem. 2007 Jan;100(1):23-35. Epub 2006 Nov 20.

18.

Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain.

Nistor M, Don M, Parekh M, Sarsoza F, Goodus M, Lopez GE, Kawas C, Leverenz J, Doran E, Lott IT, Hill M, Head E.

Neurobiol Aging. 2007 Oct;28(10):1493-506. Epub 2006 Aug 9.

19.

A specific amyloid-beta protein assembly in the brain impairs memory.

Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, Gallagher M, Ashe KH.

Nature. 2006 Mar 16;440(7082):352-7.

PMID:
16541076
20.

Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology.

Oddo S, Caccamo A, Tran L, Lambert MP, Glabe CG, Klein WL, LaFerla FM.

J Biol Chem. 2006 Jan 20;281(3):1599-604. Epub 2005 Nov 10.

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