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HELP (HpaII tiny fragment enrichment by ligation-mediated PCR) assay for DNA methylation profiling of primary normal and malignant B lymphocytes.

Shaknovich R, Figueroa ME, Melnick A.

Methods Mol Biol. 2010;632:191-201. doi: 10.1007/978-1-60761-663-4_12.


DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

Figueroa ME, Lugthart S, Li Y, Erpelinck-Verschueren C, Deng X, Christos PJ, Schifano E, Booth J, van Putten W, Skrabanek L, Campagne F, Mazumdar M, Greally JM, Valk PJ, Löwenberg B, Delwel R, Melnick A.

Cancer Cell. 2010 Jan 19;17(1):13-27. doi: 10.1016/j.ccr.2009.11.020. Epub 2010 Jan 7.


Histone deacetylase inhibitors: Potential in cancer therapy.

Marks PA, Xu WS.

J Cell Biochem. 2009 Jul 1;107(4):600-8. doi: 10.1002/jcb.22185. Review.


Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes.

Watanabe Y, Kim HS, Castoro RJ, Chung W, Estecio MR, Kondo K, Guo Y, Ahmed SS, Toyota M, Itoh F, Suk KT, Cho MY, Shen L, Jelinek J, Issa JP.

Gastroenterology. 2009 Jun;136(7):2149-58. doi: 10.1053/j.gastro.2009.02.085. Epub 2009 Apr 16.


Hunting for the 5th base: Techniques for analyzing DNA methylation.

Ammerpohl O, Martín-Subero JI, Richter J, Vater I, Siebert R.

Biochim Biophys Acta. 2009 Sep;1790(9):847-62. doi: 10.1016/j.bbagen.2009.02.001. Epub 2009 Feb 9. Review.


Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer.

Tommasi S, Karm DL, Wu X, Yen Y, Pfeifer GP.

Breast Cancer Res. 2009;11(1):R14. doi: 10.1186/bcr2233. Epub 2009 Feb 27.


Aberrant promotor methylation in MDS hematopoietic cells during in vitro lineage specific differentiation is differently associated with DNMT isoforms.

Hopfer O, Komor M, Koehler IS, Freitag C, Schulze M, Hoelzer D, Thiel E, Hofmann WK.

Leuk Res. 2009 Mar;33(3):434-42. doi: 10.1016/j.leukres.2008.08.014. Epub 2008 Sep 30.


Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas.

Palomero T, Ferrando A.

Clin Cancer Res. 2008 Sep 1;14(17):5314-7. doi: 10.1158/1078-0432.CCR-07-4864. Review.


Advances in the understanding of mantle cell lymphoma.

Jares P, Campo E.

Br J Haematol. 2008 Jun;142(2):149-65. doi: 10.1111/j.1365-2141.2008.07124.x. Epub 2008 Apr 10. Review.


PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer.

Yu JS, Koujak S, Nagase S, Li CM, Su T, Wang X, Keniry M, Memeo L, Rojtman A, Mansukhani M, Hibshoosh H, Tycko B, Parsons R.

Oncogene. 2008 Aug 7;27(34):4657-65. doi: 10.1038/onc.2008.101. Epub 2008 Apr 14.


A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor.

Turner NC, Lord CJ, Iorns E, Brough R, Swift S, Elliott R, Rayter S, Tutt AN, Ashworth A.

EMBO J. 2008 May 7;27(9):1368-77. doi: 10.1038/emboj.2008.61. Epub 2008 Apr 3.


An analytical pipeline for genomic representations used for cytosine methylation studies.

Thompson RF, Reimers M, Khulan B, Gissot M, Richmond TA, Chen Q, Zheng X, Kim K, Greally JM.

Bioinformatics. 2008 May 1;24(9):1161-7. doi: 10.1093/bioinformatics/btn096. Epub 2008 Mar 18.


Frequent epigenetic inactivation of Rb1 in addition to p15 and p16 in mantle cell and follicular lymphoma.

Chim CS, Wong KY, Loong F, Lam WW, Srivastava G.

Hum Pathol. 2007 Dec;38(12):1849-57. Epub 2007 Sep 27.


Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas.

Ripperger T, von Neuhoff N, Kamphues K, Emura M, Lehmann U, Tauscher M, Schraders M, Groenen P, Skawran B, Rudolph C, Callet-Bauchu E, van Krieken JH, Schlegelberger B, Steinemann D.

Haematologica. 2007 Apr;92(4):460-8.


Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical.

Zhao X, Lapalombella R, Joshi T, Cheney C, Gowda A, Hayden-Ledbetter MS, Baum PR, Lin TS, Jarjoura D, Lehman A, Kussewitt D, Lee RJ, Caligiuri MA, Tridandapani S, Muthusamy N, Byrd JC.

Blood. 2007 Oct 1;110(7):2569-77. Epub 2007 Apr 17.


The epigenomics of cancer.

Jones PA, Baylin SB.

Cell. 2007 Feb 23;128(4):683-92. Review.


DNA hypomethylation and human diseases.

Wilson AS, Power BE, Molloy PL.

Biochim Biophys Acta. 2007 Jan;1775(1):138-62. Epub 2006 Sep 1. Review.


Comparative isoschizomer profiling of cytosine methylation: the HELP assay.

Khulan B, Thompson RF, Ye K, Fazzari MJ, Suzuki M, Stasiek E, Figueroa ME, Glass JL, Chen Q, Montagna C, Hatchwell E, Selzer RR, Richmond TA, Green RD, Melnick A, Greally JM.

Genome Res. 2006 Aug;16(8):1046-55. Epub 2006 Jun 29.

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