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Items: 1 to 20 of 21

1.

Potential of immunomodulatory host defense peptides as novel anti-infectives.

Easton DM, Nijnik A, Mayer ML, Hancock RE.

Trends Biotechnol. 2009 Oct;27(10):582-90. doi: 10.1016/j.tibtech.2009.07.004. Epub 2009 Aug 14. Review.

PMID:
19683819
2.

Mechanisms of antimicrobial, cytolytic, and cell-penetrating peptides: from kinetics to thermodynamics.

Almeida PF, Pokorny A.

Biochemistry. 2009 Sep 1;48(34):8083-93. doi: 10.1021/bi900914g.

3.

Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity.

Rathinakumar R, Walkenhorst WF, Wimley WC.

J Am Chem Soc. 2009 Jun 10;131(22):7609-17. doi: 10.1021/ja8093247.

4.

Enabling a systems biology approach to immunology: focus on innate immunity.

Gardy JL, Lynn DJ, Brinkman FS, Hancock RE.

Trends Immunol. 2009 Jun;30(6):249-62. doi: 10.1016/j.it.2009.03.009. Epub 2009 May 8. Review.

PMID:
19428301
5.

Antibiotic-resistant bugs in the 21st century--a clinical super-challenge.

Arias CA, Murray BE.

N Engl J Med. 2009 Jan 29;360(5):439-43. doi: 10.1056/NEJMp0804651. No abstract available.

6.

Magainin 2 in action: distinct modes of membrane permeabilization in living bacterial and mammalian cells.

Imura Y, Choda N, Matsuzaki K.

Biophys J. 2008 Dec 15;95(12):5757-65. doi: 10.1529/biophysj.108.133488. Epub 2008 Oct 3.

7.

Biomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes.

Rathinakumar R, Wimley WC.

J Am Chem Soc. 2008 Jul 30;130(30):9849-58. doi: 10.1021/ja8017863. Epub 2008 Jul 9.

8.

Infection control as a major World Health Organization priority for developing countries.

Pittet D, Allegranzi B, Storr J, Bagheri Nejad S, Dziekan G, Leotsakos A, Donaldson L.

J Hosp Infect. 2008 Apr;68(4):285-92. doi: 10.1016/j.jhin.2007.12.013. Epub 2008 Mar 10. Review.

PMID:
18329137
9.

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances.

Wiegand I, Hilpert K, Hancock RE.

Nat Protoc. 2008;3(2):163-75. doi: 10.1038/nprot.2007.521.

PMID:
18274517
10.

Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005.

Klein E, Smith DL, Laxminarayan R.

Emerg Infect Dis. 2007 Dec;13(12):1840-6. doi: 10.3201/eid1312.070629.

11.
12.

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.

Hancock RE, Sahl HG.

Nat Biotechnol. 2006 Dec;24(12):1551-7. Review.

PMID:
17160061
13.

Rational combinatorial design of pore-forming beta-sheet peptides.

Rausch JM, Marks JR, Wimley WC.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10511-5. Epub 2005 Jul 14.

14.

Mammalian defensins in the antimicrobial immune response.

Selsted ME, Ouellette AJ.

Nat Immunol. 2005 Jun;6(6):551-7. Review.

PMID:
15908936
15.

Multidimensional signatures in antimicrobial peptides.

Yount NY, Yeaman MR.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-8. Epub 2004 Apr 26.

16.

Mechanisms of antimicrobial peptide action and resistance.

Yeaman MR, Yount NY.

Pharmacol Rev. 2003 Mar;55(1):27-55. Review.

17.

Transcriptional profile of the Escherichia coli response to the antimicrobial insect peptide cecropin A.

Hong RW, Shchepetov M, Weiser JN, Axelsen PH.

Antimicrob Agents Chemother. 2003 Jan;47(1):1-6.

18.

Mode of action of membrane active antimicrobial peptides.

Shai Y.

Biopolymers. 2002;66(4):236-48. Review.

PMID:
12491537
19.

A high-throughput screen for identifying transmembrane pore-forming peptides.

Rausch JM, Wimley WC.

Anal Biochem. 2001 Jun 15;293(2):258-63.

PMID:
11399041
20.

Structure, function, and membrane integration of defensins.

White SH, Wimley WC, Selsted ME.

Curr Opin Struct Biol. 1995 Aug;5(4):521-7. Review.

PMID:
8528769

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