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Items: 1 to 20 of 48

1.

A G1 checkpoint mediated by the retinoblastoma protein that is dispensable in terminal differentiation but essential for senescence.

Talluri S, Isaac CE, Ahmad M, Henley SA, Francis SM, Martens AL, Bremner R, Dick FA.

Mol Cell Biol. 2010 Feb;30(4):948-60. doi: 10.1128/MCB.01168-09. Epub 2009 Dec 14.

2.

ChIP-seq: advantages and challenges of a maturing technology.

Park PJ.

Nat Rev Genet. 2009 Oct;10(10):669-80. doi: 10.1038/nrg2641. Epub 2009 Sep 8. Review.

3.

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.

Coppé JP, Patil CK, Rodier F, Sun Y, Muñoz DP, Goldstein J, Nelson PS, Desprez PY, Campisi J.

PLoS Biol. 2008 Dec 2;6(12):2853-68. doi: 10.1371/journal.pbio.0060301.

4.

Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine.

Guo J, Longshore S, Nair R, Warner BW.

J Biol Chem. 2009 Jan 2;284(1):134-40. doi: 10.1074/jbc.M806133200. Epub 2008 Nov 3.

5.

Model-based analysis of ChIP-Seq (MACS).

Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS.

Genome Biol. 2008;9(9):R137. doi: 10.1186/gb-2008-9-9-r137. Epub 2008 Sep 17.

6.

Control of the reversibility of cellular quiescence by the transcriptional repressor HES1.

Sang L, Coller HA, Roberts JM.

Science. 2008 Aug 22;321(5892):1095-100. doi: 10.1126/science.1155998.

7.

Cellular mechanisms of tumour suppression by the retinoblastoma gene.

Burkhart DL, Sage J.

Nat Rev Cancer. 2008 Sep;8(9):671-82. doi: 10.1038/nrc2399. Review.

PMID:
18650841
8.

Cell cycle machinery: links with genesis and treatment of breast cancer.

Butt AJ, Caldon CE, McNeil CM, Swarbrick A, Musgrove EA, Sutherland RL.

Adv Exp Med Biol. 2008;630:189-205. Review.

PMID:
18637492
9.

Cellular senescence in vivo: a barrier to tumorigenesis.

Prieur A, Peeper DS.

Curr Opin Cell Biol. 2008 Apr;20(2):150-5. doi: 10.1016/j.ceb.2008.01.007. Epub 2008 Mar 18. Review.

PMID:
18353625
10.

An oncogene-induced DNA damage model for cancer development.

Halazonetis TD, Gorgoulis VG, Bartek J.

Science. 2008 Mar 7;319(5868):1352-5. doi: 10.1126/science.1140735. Review.

PMID:
18323444
11.

Many roads lead to oncogene-induced senescence.

Courtois-Cox S, Jones SL, Cichowski K.

Oncogene. 2008 May 1;27(20):2801-9. doi: 10.1038/sj.onc.1210950. Epub 2008 Jan 14. Review.

PMID:
18193093
12.

Replicational stress selects for p53 mutation.

Marusyk A, DeGregori J.

Cell Cycle. 2007 Sep 1;6(17):2148-51. Epub 2007 Jul 10.

13.

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.

Massie CE, Adryan B, Barbosa-Morais NL, Lynch AG, Tran MG, Neal DE, Mills IG.

EMBO Rep. 2007 Sep;8(9):871-8. Epub 2007 Aug 17.

14.

Cellular senescence: when bad things happen to good cells.

Campisi J, d'Adda di Fagagna F.

Nat Rev Mol Cell Biol. 2007 Sep;8(9):729-40. Review.

PMID:
17667954
15.

Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing.

Robertson G, Hirst M, Bainbridge M, Bilenky M, Zhao Y, Zeng T, Euskirchen G, Bernier B, Varhol R, Delaney A, Thiessen N, Griffith OL, He A, Marra M, Snyder M, Jones S.

Nat Methods. 2007 Aug;4(8):651-7. Epub 2007 Jun 11.

PMID:
17558387
16.

RB loss promotes aberrant ploidy by deregulating levels and activity of DNA replication factors.

Srinivasan SV, Mayhew CN, Schwemberger S, Zagorski W, Knudsen ES.

J Biol Chem. 2007 Aug 17;282(33):23867-77. Epub 2007 Jun 6.

17.

HPV related VIN: highly proliferative and diminished responsiveness to extracellular signals.

Santegoets LA, Seters Mv, Helmerhorst TJ, Heijmans-Antonissen C, Hanifi-Moghaddam P, Ewing PC, van Ijcken WF, van der Spek PJ, van der Meijden WI, Blok LJ.

Int J Cancer. 2007 Aug 15;121(4):759-66.

18.

Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function.

Markey MP, Bergseid J, Bosco EE, Stengel K, Xu H, Mayhew CN, Schwemberger SJ, Braden WA, Jiang Y, Babcock GF, Jegga AG, Aronow BJ, Reed MF, Wang JY, Knudsen ES.

Oncogene. 2007 Sep 20;26(43):6307-18. Epub 2007 Apr 23.

PMID:
17452985
19.
20.

Kinase-independent function of cyclin E.

Geng Y, Lee YM, Welcker M, Swanger J, Zagozdzon A, Winer JD, Roberts JM, Kaldis P, Clurman BE, Sicinski P.

Mol Cell. 2007 Jan 12;25(1):127-39.

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