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Items: 1 to 20 of 66

1.

Amyloid deposition is associated with impaired default network function in older persons without dementia.

Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA.

Neuron. 2009 Jul 30;63(2):178-88. doi: 10.1016/j.neuron.2009.07.003.

2.

Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease.

Reiman EM, Chen K, Liu X, Bandy D, Yu M, Lee W, Ayutyanont N, Keppler J, Reeder SA, Langbaum JB, Alexander GE, Klunk WE, Mathis CA, Price JC, Aizenstein HJ, DeKosky ST, Caselli RJ.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6820-5. doi: 10.1073/pnas.0900345106. Epub 2009 Apr 3.

3.

Detection of isolated cerebrovascular beta-amyloid with Pittsburgh compound B.

Greenberg SM, Grabowski T, Gurol ME, Skehan ME, Nandigam RN, Becker JA, Garcia-Alloza M, Prada C, Frosch MP, Rosand J, Viswanathan A, Smith EE, Johnson KA.

Ann Neurol. 2008 Nov;64(5):587-91. doi: 10.1002/ana.21528.

4.

Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects.

Mormino EC, Kluth JT, Madison CM, Rabinovici GD, Baker SL, Miller BL, Koeppe RA, Mathis CA, Weiner MW, Jagust WJ; Alzheimer's Disease Neuroimaging Initiative.

Brain. 2009 May;132(Pt 5):1310-23. doi: 10.1093/brain/awn320. Epub 2008 Nov 28.

5.

Frequent amyloid deposition without significant cognitive impairment among the elderly.

Aizenstein HJ, Nebes RD, Saxton JA, Price JC, Mathis CA, Tsopelas ND, Ziolko SK, James JA, Snitz BE, Houck PR, Bi W, Cohen AD, Lopresti BJ, DeKosky ST, Halligan EM, Klunk WE.

Arch Neurol. 2008 Nov;65(11):1509-17. doi: 10.1001/archneur.65.11.1509.

6.

Alzheimer disease and cognitive reserve: variation of education effect with carbon 11-labeled Pittsburgh Compound B uptake.

Roe CM, Mintun MA, D'Angelo G, Xiong C, Grant EA, Morris JC.

Arch Neurol. 2008 Nov;65(11):1467-71. doi: 10.1001/archneur.65.11.1467.

7.

Imaging amyloid deposition in Lewy body diseases.

Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, Mathis CA, Elmaleh DR, Shoup T, Fischman AJ, Hyman BT, Growdon JH, Johnson KA.

Neurology. 2008 Sep 16;71(12):903-10. doi: 10.1212/01.wnl.0000326146.60732.d6.

8.

The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals.

Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL.

Cereb Cortex. 2009 Mar;19(3):497-510. doi: 10.1093/cercor/bhn113. Epub 2008 Jul 16.

9.

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ.

Nat Med. 2008 Aug;14(8):837-42. doi: 10.1038/nm1782. Epub 2008 Jun 22.

10.

11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment.

Jack CR Jr, Lowe VJ, Senjem ML, Weigand SD, Kemp BJ, Shiung MM, Knopman DS, Boeve BF, Klunk WE, Mathis CA, Petersen RC.

Brain. 2008 Mar;131(Pt 3):665-80. doi: 10.1093/brain/awm336. Epub 2008 Feb 7.

11.

Brain volume decline in aging: evidence for a relation between socioeconomic status, preclinical Alzheimer disease, and reserve.

Fotenos AF, Mintun MA, Snyder AZ, Morris JC, Buckner RL.

Arch Neurol. 2008 Jan;65(1):113-20. doi: 10.1001/archneurol.2007.27.

PMID:
18195148
12.

Cognitive reserve hypothesis: Pittsburgh Compound B and fluorodeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease.

Kemppainen NM, Aalto S, Karrasch M, Någren K, Savisto N, Oikonen V, Viitanen M, Parkkola R, Rinne JO.

Ann Neurol. 2008 Jan;63(1):112-8.

PMID:
18023012
13.

Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease.

Pike KE, Savage G, Villemagne VL, Ng S, Moss SA, Maruff P, Mathis CA, Klunk WE, Masters CL, Rowe CC.

Brain. 2007 Nov;130(Pt 11):2837-44. Epub 2007 Oct 10.

PMID:
17928318
14.

Imaging of amyloid burden and distribution in cerebral amyloid angiopathy.

Johnson KA, Gregas M, Becker JA, Kinnecom C, Salat DH, Moran EK, Smith EE, Rosand J, Rentz DM, Klunk WE, Mathis CA, Price JC, Dekosky ST, Fischman AJ, Greenberg SM.

Ann Neurol. 2007 Sep;62(3):229-34.

PMID:
17683091
15.

A common neural network for cognitive reserve in verbal and object working memory in young but not old.

Stern Y, Zarahn E, Habeck C, Holtzer R, Rakitin BC, Kumar A, Flynn J, Steffener J, Brown T.

Cereb Cortex. 2008 Apr;18(4):959-67. Epub 2007 Aug 3.

16.

Imaging beta-amyloid burden in aging and dementia.

Rowe CC, Ng S, Ackermann U, Gong SJ, Pike K, Savage G, Cowie TF, Dickinson KL, Maruff P, Darby D, Smith C, Woodward M, Merory J, Tochon-Danguy H, O'Keefe G, Klunk WE, Mathis CA, Price JC, Masters CL, Villemagne VL.

Neurology. 2007 May 15;68(20):1718-25.

PMID:
17502554
17.

PET imaging of amyloid deposition in patients with mild cognitive impairment.

Forsberg A, Engler H, Almkvist O, Blomquist G, Hagman G, Wall A, Ringheim A, Långström B, Nordberg A.

Neurobiol Aging. 2008 Oct;29(10):1456-65. Epub 2007 May 11.

PMID:
17499392
18.

11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration.

Rabinovici GD, Furst AJ, O'Neil JP, Racine CA, Mormino EC, Baker SL, Chetty S, Patel P, Pagliaro TA, Klunk WE, Mathis CA, Rosen HJ, Miller BL, Jagust WJ.

Neurology. 2007 Apr 10;68(15):1205-12.

PMID:
17420404
19.

Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report.

Bacskai BJ, Frosch MP, Freeman SH, Raymond SB, Augustinack JC, Johnson KA, Irizarry MC, Klunk WE, Mathis CA, Dekosky ST, Greenberg SM, Hyman BT, Growdon JH.

Arch Neurol. 2007 Mar;64(3):431-4.

PMID:
17353389
20.

Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study.

Edison P, Archer HA, Hinz R, Hammers A, Pavese N, Tai YF, Hotton G, Cutler D, Fox N, Kennedy A, Rossor M, Brooks DJ.

Neurology. 2007 Feb 13;68(7):501-8. Epub 2006 Oct 25.

PMID:
17065593

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