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Items: 20

1.

Triptolide induces anti-inflammatory cellular responses.

Matta R, Wang X, Ge H, Ray W, Nelin LD, Liu Y.

Am J Transl Res. 2009 Mar 5;1(3):267-82.

PMID:
19956437
2.

Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.

Vispé S, DeVries L, Créancier L, Besse J, Bréand S, Hobson DJ, Svejstrup JQ, Annereau JP, Cussac D, Dumontet C, Guilbaud N, Barret JM, Bailly C.

Mol Cancer Ther. 2009 Oct;8(10):2780-90. doi: 10.1158/1535-7163.MCT-09-0549. Epub 2009 Oct 6.

PMID:
19808979
3.

Common pathways for activation of proinflammatory gene expression by G protein-coupled receptors in primary lung epithelial and endothelial cells.

Chang W, Chen J, Schlueter CF, Hoyle GW.

Exp Lung Res. 2009 May;35(4):324-43. doi: 10.1080/01902140802712738.

PMID:
19415549
4.

The suppressive effect of triptolide on chronic colitis and TNF-alpha/TNFR2 signal pathway in interleukin-10 deficient mice.

Wei X, Gong J, Zhu J, Wang P, Li N, Zhu W, Li J.

Clin Immunol. 2008 Nov;129(2):211-8. doi: 10.1016/j.clim.2008.07.018. Epub 2008 Aug 30.

PMID:
18757245
5.

Mitigation of chlorine-induced lung injury by low-molecular-weight antioxidants.

Leustik M, Doran S, Bracher A, Williams S, Squadrito GL, Schoeb TR, Postlethwait E, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L733-43. doi: 10.1152/ajplung.90240.2008. Epub 2008 Aug 15.

PMID:
18708632
6.

Acute lung injury induced by chlorine inhalation in C57BL/6 and FVB/N mice.

Tian X, Tao H, Brisolara J, Chen J, Rando RJ, Hoyle GW.

Inhal Toxicol. 2008 Jul;20(9):783-93. doi: 10.1080/08958370802007841 .

PMID:
18645717
7.

Mycophenolate mofetil and triptolide alleviating airway inflammation in asthmatic model mice partly by inhibiting bone marrow eosinophilopoiesis.

Mao H, Chen XR, Yi Q, Li SY, Wang ZL, Li FY.

Int Immunopharmacol. 2008 Jul;8(7):1039-48. doi: 10.1016/j.intimp.2008.03.009. Epub 2008 Apr 11.

PMID:
18486916
8.

Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.

Wang Y, Mei Y, Feng D, Xu L.

J Neurosci Res. 2008 Aug 15;86(11):2441-9. doi: 10.1002/jnr.21683.

PMID:
18438925
9.

(5R)-5-hydroxytriptolide (LLDT-8) protects against bleomycin-induced lung fibrosis in mice.

Ren YX, Zhou R, Tang W, Wang WH, Li YC, Yang YF, Zuo JP.

Acta Pharmacol Sin. 2007 Apr;28(4):518-25.

PMID:
17376291
10.

Triptolide, a diterpenoid triepoxide, suppresses inflammation and cartilage destruction in collagen-induced arthritis mice.

Lin N, Liu C, Xiao C, Jia H, Imada K, Wu H, Ito A.

Biochem Pharmacol. 2007 Jan 1;73(1):136-46. Epub 2006 Sep 6.

PMID:
17097618
11.

Tachykinin-1 receptor stimulates proinflammatory gene expression in lung epithelial cells through activation of NF-kappaB via a G(q)-dependent pathway.

Williams R, Zou X, Hoyle GW.

Am J Physiol Lung Cell Mol Physiol. 2007 Feb;292(2):L430-7. Epub 2006 Oct 13.

PMID:
17041011
12.

Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death.

Westerheide SD, Kawahara TL, Orton K, Morimoto RI.

J Biol Chem. 2006 Apr 7;281(14):9616-22. Epub 2006 Feb 9. Erratum in: J Biol Chem. 2006 Jul 28;281(30):21575.

PMID:
16469748
13.

Chlorine: state of the art.

Evans RB.

Lung. 2005 May-Jun;183(3):151-67. Review.

PMID:
16078037
14.

Chlorine-induced injury to the airways in mice.

Martin JG, Campbell HR, Iijima H, Gautrin D, Malo JL, Eidelman DH, Hamid Q, Maghni K.

Am J Respir Crit Care Med. 2003 Sep 1;168(5):568-74. Epub 2003 Apr 30.

PMID:
12724121
15.

PG490-88, a derivative of triptolide, attenuates obliterative airway disease in a mouse heterotopic tracheal allograft model.

Leonard CT, Soccal PM, Berry GJ, Doyle RL, Theodore J, Duncan SR, Rosen GD.

J Heart Lung Transplant. 2002 Dec;21(12):1314-8.

PMID:
12490278
16.

Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells.

Jiang XH, Wong BC, Lin MC, Zhu GH, Kung HF, Jiang SH, Yang D, Lam SK.

Oncogene. 2001 Nov 29;20(55):8009-18.

PMID:
11753684
17.

PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis.

Krishna G, Liu K, Shigemitsu H, Gao M, Raffin TA, Rosen GD.

Am J Pathol. 2001 Mar;158(3):997-1004.

PMID:
11238047
18.

Anti-inflammatory effects of triptolide in human bronchial epithelial cells.

Zhao G, Vaszar LT, Qiu D, Shi L, Kao PN.

Am J Physiol Lung Cell Mol Physiol. 2000 Nov;279(5):L958-66.

PMID:
11053033
19.
20.

Exposure to chlorine gas: effects on pulmonary function and morphology in anaesthetised and mechanically ventilated pigs.

Gunnarsson M, Walther SM, Seidal T, Bloom GD, Lennquist S.

J Appl Toxicol. 1998 Jul-Aug;18(4):249-55.

PMID:
9719424

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