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Items: 1 to 20 of 57

1.

TAK1 is an essential regulator of BMP signalling in cartilage.

Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH.

EMBO J. 2009 Jul 22;28(14):2028-41. doi: 10.1038/emboj.2009.162. Epub 2009 Jun 18.

2.

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation.

Retting KN, Song B, Yoon BS, Lyons KM.

Development. 2009 Apr;136(7):1093-104. doi: 10.1242/dev.029926. Epub 2009 Feb 18.

3.

Reduced limb length and worsened osteoarthritis in adult mice after genetic inhibition of p38 MAP kinase activity in cartilage.

Namdari S, Wei L, Moore D, Chen Q.

Arthritis Rheum. 2008 Nov;58(11):3520-9. doi: 10.1002/art.23999.

4.

A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis.

Koyama E, Shibukawa Y, Nagayama M, Sugito H, Young B, Yuasa T, Okabe T, Ochiai T, Kamiya N, Rountree RB, Kingsley DM, Iwamoto M, Enomoto-Iwamoto M, Pacifici M.

Dev Biol. 2008 Apr 1;316(1):62-73. doi: 10.1016/j.ydbio.2008.01.012. Epub 2008 Jan 26.

5.
7.

Transcription factor ERG and joint and articular cartilage formation during mouse limb and spine skeletogenesis.

Iwamoto M, Tamamura Y, Koyama E, Komori T, Takeshita N, Williams JA, Nakamura T, Enomoto-Iwamoto M, Pacifici M.

Dev Biol. 2007 May 1;305(1):40-51. Epub 2007 Feb 7.

8.

BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway.

Jin EJ, Lee SY, Choi YA, Jung JC, Bang OS, Kang SS.

Mol Cells. 2006 Dec 31;22(3):353-9.

9.

Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis.

Bandyopadhyay A, Tsuji K, Cox K, Harfe BD, Rosen V, Tabin CJ.

PLoS Genet. 2006 Dec;2(12):e216. Epub 2006 Nov 6.

10.

Role of canonical Wnt-signalling in joint formation.

Später D, Hill TP, Gruber M, Hartmann C.

Eur Cell Mater. 2006 Nov 17;12:71-80.

11.

BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways.

Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM.

Development. 2006 Dec;133(23):4667-78. Epub 2006 Oct 25.

12.

Essential role of TAK1 in thymocyte development and activation.

Liu HH, Xie M, Schneider MD, Chen ZJ.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11677-82. Epub 2006 Jul 20.

13.

Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes.

Li TF, Chen D, Wu Q, Chen M, Sheu TJ, Schwarz EM, Drissi H, Zuscik M, O'Keefe RJ.

J Biol Chem. 2006 Jul 28;281(30):21296-304. Epub 2006 May 10.

14.

Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation.

Kavanagh E, Church VL, Osborne AC, Lamb KJ, Archer CW, Francis-West PH, Pitsillides AA.

Dev Dyn. 2006 Mar;235(3):826-34.

15.

Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation.

Zhang R, Murakami S, Coustry F, Wang Y, de Crombrugghe B.

Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):365-70. Epub 2005 Dec 30.

16.

Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.

Li TF, Darowish M, Zuscik MJ, Chen D, Schwarz EM, Rosier RN, Drissi H, O'Keefe RJ.

J Bone Miner Res. 2006 Jan;21(1):4-16. Epub 2005 Sep 19.

17.
18.

Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors.

Hoffmann A, Preobrazhenska O, Wodarczyk C, Medler Y, Winkel A, Shahab S, Huylebroeck D, Gross G, Verschueren K.

J Biol Chem. 2005 Jul 22;280(29):27271-83. Epub 2005 May 23.

20.

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.

Hill TP, Später D, Taketo MM, Birchmeier W, Hartmann C.

Dev Cell. 2005 May;8(5):727-38.

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