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Decreased ERK and JNK signaling contribute to gene overexpression in "senescent" CD4+CD28- T cells through epigenetic mechanisms.

Chen Y, Gorelik GJ, Strickland FM, Richardson BC.

J Leukoc Biol. 2010 Jan;87(1):137-45. doi: 10.1189/jlb.0809562. Epub 2009 Oct 20.


Modulation of long-term memory for object recognition via HDAC inhibition.

Stefanko DP, Barrett RM, Ly AR, Reolon GK, Wood MA.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9447-52. doi: 10.1073/pnas.0903964106. Epub 2009 May 26.


HDAC2 negatively regulates memory formation and synaptic plasticity.

Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH.

Nature. 2009 May 7;459(7243):55-60. doi: 10.1038/nature07925.


Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60.

Wu J, Xie N, Wu Z, Zhang Y, Zheng YG.

Bioorg Med Chem. 2009 Feb 1;17(3):1381-6. doi: 10.1016/j.bmc.2008.12.014. Epub 2008 Dec 24.


Mechanism of p300 specific histone acetyltransferase inhibition by small molecules.

Arif M, Pradhan SK, Thanuja GR, Vedamurthy BM, Agrawal S, Dasgupta D, Kundu TK.

J Med Chem. 2009 Jan 22;52(2):267-77. doi: 10.1021/jm800657z.


Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity.

Kim D, Frank CL, Dobbin MM, Tsunemoto RK, Tu W, Peng PL, Guan JS, Lee BH, Moy LY, Giusti P, Broodie N, Mazitschek R, Delalle I, Haggarty SJ, Neve RL, Lu Y, Tsai LH.

Neuron. 2008 Dec 10;60(5):803-17. doi: 10.1016/j.neuron.2008.10.015.


The effects of acute 17beta-estradiol treatment on gene expression in the young female mouse hippocampus.

Pechenino AS, Frick KM.

Neurobiol Learn Mem. 2009 Mar;91(3):315-22. doi: 10.1016/j.nlm.2008.09.017. Epub 2008 Nov 8.


Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke.

Adenuga D, Yao H, March TH, Seagrave J, Rahman I.

Am J Respir Cell Mol Biol. 2009 Apr;40(4):464-73. doi: 10.1165/rcmb.2008-0255OC. Epub 2008 Oct 16.


Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs.

Zhao Z, Zhang HT, Bootzin E, Millan MJ, O'Donnell JM.

Neuropsychopharmacology. 2009 May;34(6):1467-81. doi: 10.1038/npp.2008.183. Epub 2008 Oct 15.


Histone deacetylase inhibitors in cancer therapy.

Lee MJ, Kim YS, Kummar S, Giaccone G, Trepel JB.

Curr Opin Oncol. 2008 Nov;20(6):639-49. doi: 10.1097/CCO.0b013e3283127095. Review.


Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors.

Fernandez SM, Lewis MC, Pechenino AS, Harburger LL, Orr PT, Gresack JE, Schafe GE, Frick KM.

J Neurosci. 2008 Aug 27;28(35):8660-7. doi: 10.1523/JNEUROSCI.1968-08.2008.


Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development.

MacDonald JL, Roskams AJ.

Dev Dyn. 2008 Aug;237(8):2256-67. doi: 10.1002/dvdy.21626.


DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity.

Miller CA, Campbell SL, Sweatt JD.

Neurobiol Learn Mem. 2008 May;89(4):599-603. Epub 2007 Sep 18.


Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation.

Vecsey CG, Hawk JD, Lattal KM, Stein JM, Fabian SA, Attner MA, Cabrera SM, McDonough CB, Brindle PK, Abel T, Wood MA.

J Neurosci. 2007 Jun 6;27(23):6128-40.


Recovery of learning and memory is associated with chromatin remodelling.

Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH.

Nature. 2007 May 10;447(7141):178-82. Epub 2007 Apr 29.


Covalent modification of DNA regulates memory formation.

Miller CA, Sweatt JD.

Neuron. 2007 Mar 15;53(6):857-69. Erratum in: Neuron. 2008 Sep 25;59(6):1051.


ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning.

Chwang WB, O'Riordan KJ, Levenson JM, Sweatt JD.

Learn Mem. 2006 May-Jun;13(3):322-8.

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