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Items: 1 to 20 of 167

1.

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

Matsui T, Leung D, Miyashita H, Maksakova IA, Miyachi H, Kimura H, Tachibana M, Lorincz MC, Shinkai Y.

Nature. 2010 Apr 8;464(7290):927-31. doi: 10.1038/nature08858. Epub 2010 Feb 17. Erratum in: Nature. 2014 Sep 4;513(7516):128.

PMID:
20164836
2.

Histone modification levels are predictive for gene expression.

Karlić R, Chung HR, Lasserre J, Vlahovicek K, Vingron M.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2926-31. doi: 10.1073/pnas.0909344107. Epub 2010 Feb 1.

3.

Dynamic changes in the human methylome during differentiation.

Laurent L, Wong E, Li G, Huynh T, Tsirigos A, Ong CT, Low HM, Kin Sung KW, Rigoutsos I, Loring J, Wei CL.

Genome Res. 2010 Mar;20(3):320-31. doi: 10.1101/gr.101907.109. Epub 2010 Feb 4.

4.

Genetic evidence for Dnmt3a-dependent imprinting during oocyte growth obtained by conditional knockout with Zp3-Cre and complete exclusion of Dnmt3b by chimera formation.

Kaneda M, Hirasawa R, Chiba H, Okano M, Li E, Sasaki H.

Genes Cells. 2010 Mar;15(3):169-79. doi: 10.1111/j.1365-2443.2009.01374.x. Epub 2010 Feb 1.

5.

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus.

Javierre BM, Fernandez AF, Richter J, Al-Shahrour F, Martin-Subero JI, Rodriguez-Ubreva J, Berdasco M, Fraga MF, O'Hanlon TP, Rider LG, Jacinto FV, Lopez-Longo FJ, Dopazo J, Forn M, Peinado MA, Carreño L, Sawalha AH, Harley JB, Siebert R, Esteller M, Miller FW, Ballestar E.

Genome Res. 2010 Feb;20(2):170-9. doi: 10.1101/gr.100289.109. Epub 2009 Dec 22.

6.

The multi-domain protein Np95 connects DNA methylation and histone modification.

Rottach A, Frauer C, Pichler G, Bonapace IM, Spada F, Leonhardt H.

Nucleic Acids Res. 2010 Apr;38(6):1796-804. doi: 10.1093/nar/gkp1152. Epub 2009 Dec 21.

7.

Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1.

Alhosin M, Abusnina A, Achour M, Sharif T, Muller C, Peluso J, Chataigneau T, Lugnier C, Schini-Kerth VB, Bronner C, Fuhrmann G.

Biochem Pharmacol. 2010 May 1;79(9):1251-60. doi: 10.1016/j.bcp.2009.12.015. Epub 2009 Dec 22.

PMID:
20026309
8.

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.

Horton JR, Upadhyay AK, Qi HH, Zhang X, Shi Y, Cheng X.

Nat Struct Mol Biol. 2010 Jan;17(1):38-43. doi: 10.1038/nsmb.1753. Epub 2009 Dec 20.

9.

The N-terminus of histone H3 is required for de novo DNA methylation in chromatin.

Hu JL, Zhou BO, Zhang RR, Zhang KL, Zhou JQ, Xu GL.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22187-92. doi: 10.1073/pnas.0905767106. Epub 2009 Dec 14.

10.

KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation.

Lohmann F, Loureiro J, Su H, Fang Q, Lei H, Lewis T, Yang Y, Labow M, Li E, Chen T, Kadam S.

Stem Cells. 2010 Feb;28(2):201-12. doi: 10.1002/stem.278.

11.

Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.

Cierpicki T, Risner LE, Grembecka J, Lukasik SM, Popovic R, Omonkowska M, Shultis DD, Zeleznik-Le NJ, Bushweller JH.

Nat Struct Mol Biol. 2010 Jan;17(1):62-8. doi: 10.1038/nsmb.1714. Epub 2009 Dec 13.

12.

Non-imprinted allele-specific DNA methylation on human autosomes.

Zhang Y, Rohde C, Reinhardt R, Voelcker-Rehage C, Jeltsch A.

Genome Biol. 2009;10(12):R138. doi: 10.1186/gb-2009-10-12-r138. Epub 2009 Dec 3.

13.

CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin.

Tate CM, Lee JH, Skalnik DG.

FEBS J. 2010 Jan;277(1):210-23. doi: 10.1111/j.1742-4658.2009.07475.x. Epub 2009 Nov 27. Erratum in: FEBS J. 2010 Jun;277(11):2564.

14.

CG dinucleotide periodicities recognized by the Dnmt3a-Dnmt3L complex are distinctive at retroelements and imprinted domains.

Glass JL, Fazzari MJ, Ferguson-Smith AC, Greally JM.

Mamm Genome. 2009 Sep-Oct;20(9-10):633-43. doi: 10.1007/s00335-009-9232-3. Epub 2009 Nov 17.

PMID:
19921333
15.

Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.

Liu F, Chen X, Allali-Hassani A, Quinn AM, Wasney GA, Dong A, Barsyte D, Kozieradzki I, Senisterra G, Chau I, Siarheyeva A, Kireev DB, Jadhav A, Herold JM, Frye SV, Arrowsmith CH, Brown PJ, Simeonov A, Vedadi M, Jin J.

J Med Chem. 2009 Dec 24;52(24):7950-3. doi: 10.1021/jm901543m.

16.

PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase.

Loenarz C, Ge W, Coleman ML, Rose NR, Cooper CD, Klose RJ, Ratcliffe PJ, Schofield CJ.

Hum Mol Genet. 2010 Jan 15;19(2):217-22. doi: 10.1093/hmg/ddp480. Epub 2009 Oct 19.

17.

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain.

Otani J, Nankumo T, Arita K, Inamoto S, Ariyoshi M, Shirakawa M.

EMBO Rep. 2009 Nov;10(11):1235-41. doi: 10.1038/embor.2009.218. Epub 2009 Oct 16.

18.

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies.

Urdinguio RG, Sanchez-Mut JV, Esteller M.

Lancet Neurol. 2009 Nov;8(11):1056-72. doi: 10.1016/S1474-4422(09)70262-5. Review.

PMID:
19833297
19.

DNA demethylation in hormone-induced transcriptional derepression.

Kim MS, Kondo T, Takada I, Youn MY, Yamamoto Y, Takahashi S, Matsumoto T, Fujiyama S, Shirode Y, Yamaoka I, Kitagawa H, Takeyama K, Shibuya H, Ohtake F, Kato S.

Nature. 2009 Oct 15;461(7266):1007-12. doi: 10.1038/nature08456. Erratum in: Nature. 2011 Dec 1;480(7375):132. Retraction in: Kim MS, Kondo T, Takada I, Youn MY, Yamamoto Y, Takahashi S, Matsumoto T, Fujiyama S, Shirode Y, Yamaoka I, Kitagawa H, Takeyama K, Shibuya H, Ohtake F, Kato S. Nature. 2012 Jun 14;486(7402):280.

PMID:
19829383
20.

Human DNA methylomes at base resolution show widespread epigenomic differences.

Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, Edsall L, Antosiewicz-Bourget J, Stewart R, Ruotti V, Millar AH, Thomson JA, Ren B, Ecker JR.

Nature. 2009 Nov 19;462(7271):315-22. doi: 10.1038/nature08514. Epub 2009 Oct 14.

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