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Items: 1 to 20 of 47

1.

Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.

Chelu MG, Sarma S, Sood S, Wang S, van Oort RJ, Skapura DG, Li N, Santonastasi M, Müller FU, Schmitz W, Schotten U, Anderson ME, Valderrábano M, Dobrev D, Wehrens XH.

J Clin Invest. 2009 Jul;119(7):1940-51.

2.

The Ca(v)3.2 T-type Ca(2+) channel is required for pressure overload-induced cardiac hypertrophy in mice.

Chiang CS, Huang CH, Chieng H, Chang YT, Chang D, Chen JJ, Chen YC, Chen YH, Shin HS, Campbell KP, Chen CC.

Circ Res. 2009 Feb 27;104(4):522-30. doi: 10.1161/CIRCRESAHA.108.184051. Epub 2009 Jan 2.

3.

Redox modification of ryanodine receptors contributes to sarcoplasmic reticulum Ca2+ leak in chronic heart failure.

Terentyev D, Györke I, Belevych AE, Terentyeva R, Sridhar A, Nishijima Y, de Blanco EC, Khanna S, Sen CK, Cardounel AJ, Carnes CA, Györke S.

Circ Res. 2008 Dec 5;103(12):1466-72. doi: 10.1161/CIRCRESAHA.108.184457. Epub 2008 Nov 13.

4.

Ca2+ influx through T- and L-type Ca2+ channels have different effects on myocyte contractility and induce unique cardiac phenotypes.

Jaleel N, Nakayama H, Chen X, Kubo H, MacDonnell S, Zhang H, Berretta R, Robbins J, Cribbs L, Molkentin JD, Houser SR.

Circ Res. 2008 Nov 7;103(10):1109-19. doi: 10.1161/CIRCRESAHA.108.185611. Epub 2008 Oct 2.

5.

Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation.

Sood S, Chelu MG, van Oort RJ, Skapura D, Santonastasi M, Dobrev D, Wehrens XH.

Heart Rhythm. 2008 Jul;5(7):1047-54. doi: 10.1016/j.hrthm.2008.03.030. Epub 2008 Mar 27.

6.

Does contractile Ca2+ control calcineurin-NFAT signaling and pathological hypertrophy in cardiac myocytes?

Houser SR, Molkentin JD.

Sci Signal. 2008 Jun 24;1(25):pe31. doi: 10.1126/scisignal.125pe31.

7.

Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca2+ signal integrators.

Colella M, Grisan F, Robert V, Turner JD, Thomas AP, Pozzan T.

Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2859-64. doi: 10.1073/pnas.0712316105. Epub 2008 Feb 19.

8.

Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure.

Nakayama H, Chen X, Baines CP, Klevitsky R, Zhang X, Zhang H, Jaleel N, Chua BH, Hewett TE, Robbins J, Houser SR, Molkentin JD.

J Clin Invest. 2007 Sep;117(9):2431-44.

9.

A novel early onset lethal form of catecholaminergic polymorphic ventricular tachycardia maps to chromosome 7p14-p22.

Bhuiyan ZA, Hamdan MA, Shamsi ET, Postma AV, Mannens MM, Wilde AA, Al-Gazali L.

J Cardiovasc Electrophysiol. 2007 Sep;18(10):1060-6. Epub 2007 Jul 30.

PMID:
17666061
10.

Genetic screening of calcium regulation genes in familial hypertrophic cardiomyopathy.

Chiu C, Tebo M, Ingles J, Yeates L, Arthur JW, Lind JM, Semsarian C.

J Mol Cell Cardiol. 2007 Sep;43(3):337-43. Epub 2007 Jun 30.

PMID:
17655857
11.

Scavenging free radicals by low-dose carvedilol prevents redox-dependent Ca2+ leak via stabilization of ryanodine receptor in heart failure.

Mochizuki M, Yano M, Oda T, Tateishi H, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, Ikemoto N, Matsuzaki M.

J Am Coll Cardiol. 2007 Apr 24;49(16):1722-32. Epub 2007 Apr 5.

12.

Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel.

Yamaguchi N, Takahashi N, Xu L, Smithies O, Meissner G.

J Clin Invest. 2007 May;117(5):1344-53. Epub 2007 Apr 12.

13.

Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy.

Xu M, Zhou P, Xu SM, Liu Y, Feng X, Bai SH, Bai Y, Hao XM, Han Q, Zhang Y, Wang SQ.

PLoS Biol. 2007 Feb;5(2):e21.

14.

Upregulation of TRPC1 in the development of cardiac hypertrophy.

Ohba T, Watanabe H, Murakami M, Takahashi Y, Iino K, Kuromitsu S, Mori Y, Ono K, Iijima T, Ito H.

J Mol Cell Cardiol. 2007 Mar;42(3):498-507. Epub 2006 Dec 15.

PMID:
17174323
15.

TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.

Onohara N, Nishida M, Inoue R, Kobayashi H, Sumimoto H, Sato Y, Mori Y, Nagao T, Kurose H.

EMBO J. 2006 Nov 15;25(22):5305-16. Epub 2006 Nov 2.

16.

Regulation of cardiac hypertrophy by intracellular signalling pathways.

Heineke J, Molkentin JD.

Nat Rev Mol Cell Biol. 2006 Aug;7(8):589-600. Review.

PMID:
16936699
17.

Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart.

Nakayama H, Wilkin BJ, Bodi I, Molkentin JD.

FASEB J. 2006 Aug;20(10):1660-70.

18.

Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy.

Kannankeril PJ, Mitchell BM, Goonasekera SA, Chelu MG, Zhang W, Sood S, Kearney DL, Danila CI, De Biasi M, Wehrens XH, Pautler RG, Roden DM, Taffet GE, Dirksen RT, Anderson ME, Hamilton SL.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12179-84. Epub 2006 Jul 27.

19.

MEF2 activates a genetic program promoting chamber dilation and contractile dysfunction in calcineurin-induced heart failure.

van Oort RJ, van Rooij E, Bourajjaj M, Schimmel J, Jansen MA, van der Nagel R, Doevendans PA, Schneider MD, van Echteld CJ, De Windt LJ.

Circulation. 2006 Jul 25;114(4):298-308. Epub 2006 Jul 17.

20.

Composite polymorphisms in the ryanodine receptor 2 gene associated with arrhythmogenic right ventricular cardiomyopathy.

Milting H, Lukas N, Klauke B, Körfer R, Perrot A, Osterziel KJ, Vogt J, Peters S, Thieleczek R, Varsányi M.

Cardiovasc Res. 2006 Aug 1;71(3):496-505. Epub 2006 Apr 18.

PMID:
16769042

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