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Items: 1 to 20 of 65

1.

A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling.

Wang Y, Becker D, Vass T, White J, Marrack P, Kappler JW.

PLoS Biol. 2009 Dec;7(12):e1000253. doi: 10.1371/journal.pbio.1000253. Epub 2009 Dec 1.

2.

Critical and multiple roles for the CD3epsilon intracytoplasmic tail in double negative to double positive thymocyte differentiation.

Brodeur JF, Li S, da Silva Martins M, Larose L, Dave VP.

J Immunol. 2009 Apr 15;182(8):4844-53. doi: 10.4049/jimmunol.0803679.

3.

Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin.

Wang H, Matsuzawa A, Brown SA, Zhou J, Guy CS, Tseng PH, Forbes K, Nicholson TP, Sheppard PW, Häcker H, Karin M, Vignali DA.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20197-202. doi: 10.1073/pnas.0810461105. Epub 2008 Dec 17.

4.

Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif.

Xu C, Gagnon E, Call ME, Schnell JR, Schwieters CD, Carman CV, Chou JJ, Wucherpfennig KW.

Cell. 2008 Nov 14;135(4):702-13. doi: 10.1016/j.cell.2008.09.044.

5.

Low ligand requirement for deletion and lack of synapses in positive selection enforce the gauntlet of thymic T cell maturation.

Ebert PJ, Ehrlich LI, Davis MM.

Immunity. 2008 Nov 14;29(5):734-45. doi: 10.1016/j.immuni.2008.09.014.

6.

A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation.

Ouchida R, Yamasaki S, Hikida M, Masuda K, Kawamura K, Wada A, Mochizuki S, Tagawa M, Sakamoto A, Hatano M, Tokuhisa T, Koseki H, Saito T, Kurosaki T, Wang JY.

Immunity. 2008 Jul 18;29(1):33-43. doi: 10.1016/j.immuni.2008.04.024.

7.

The proline-rich sequence of CD3epsilon as an amplifier of low-avidity TCR signaling.

Tailor P, Tsai S, Shameli A, Serra P, Wang J, Robbins S, Nagata M, Szymczak-Workman AL, Vignali DA, Santamaria P.

J Immunol. 2008 Jul 1;181(1):243-55.

8.

Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity.

Holst J, Wang H, Eder KD, Workman CJ, Boyd KL, Baquet Z, Singh H, Forbes K, Chruscinski A, Smeyne R, van Oers NS, Utz PJ, Vignali DA.

Nat Immunol. 2008 Jun;9(6):658-66. doi: 10.1038/ni.1611. Epub 2008 May 11.

PMID:
18469818
9.

The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.

Mingueneau M, Sansoni A, Grégoire C, Roncagalli R, Aguado E, Weiss A, Malissen M, Malissen B.

Nat Immunol. 2008 May;9(5):522-32. doi: 10.1038/ni.1608. Epub 2008 Apr 13.

PMID:
18408722
10.

Characterization of polyubiquitin chain structure by middle-down mass spectrometry.

Xu P, Peng J.

Anal Chem. 2008 May 1;80(9):3438-44. doi: 10.1021/ac800016w. Epub 2008 Mar 20.

11.

Generation of T-cell receptor retrogenic mice.

Holst J, Szymczak-Workman AL, Vignali KM, Burton AR, Workman CJ, Vignali DA.

Nat Protoc. 2006;1(1):406-17.

PMID:
17406263
12.

miR-181a is an intrinsic modulator of T cell sensitivity and selection.

Li QJ, Chau J, Ebert PJ, Sylvester G, Min H, Liu G, Braich R, Manoharan M, Soutschek J, Skare P, Klein LO, Davis MM, Chen CZ.

Cell. 2007 Apr 6;129(1):147-61. Epub 2007 Mar 22.

13.

Metalloproteases regulate T-cell proliferation and effector function via LAG-3.

Li N, Wang Y, Forbes K, Vignali KM, Heale BS, Saftig P, Hartmann D, Black RA, Rossi JJ, Blobel CP, Dempsey PJ, Workman CJ, Vignali DA.

EMBO J. 2007 Jan 24;26(2):494-504.

14.

Proteasome-independent functions of ubiquitin in endocytosis and signaling.

Mukhopadhyay D, Riezman H.

Science. 2007 Jan 12;315(5809):201-5. Review.

PMID:
17218518
15.

Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits.

Sigalov AB, Aivazian DA, Uversky VN, Stern LJ.

Biochemistry. 2006 Dec 26;45(51):15731-9. Epub 2006 Dec 19.

16.

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling.

Daniels MA, Teixeiro E, Gill J, Hausmann B, Roubaty D, Holmberg K, Werlen G, Holländer GA, Gascoigne NR, Palmer E.

Nature. 2006 Dec 7;444(7120):724-9. Epub 2006 Nov 1.

PMID:
17086201
17.

Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice.

Holst J, Vignali KM, Burton AR, Vignali DA.

Nat Methods. 2006 Mar;3(3):191-7. Erratum in: Nat Methods. 2006 Apr;3(4):327.

PMID:
16489336
18.

Lingering mysteries of ubiquitin-chain assembly.

Hochstrasser M.

Cell. 2006 Jan 13;124(1):27-34. Review.

20.

Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex.

Myers MD, Sosinowski T, Dragone LL, White C, Band H, Gu H, Weiss A.

Nat Immunol. 2006 Jan;7(1):57-66. Epub 2005 Dec 4.

PMID:
16327786

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