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Items: 1 to 20 of 36

1.

Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.

Efeyan A, Murga M, Martinez-Pastor B, Ortega-Molina A, Soria R, Collado M, Fernandez-Capetillo O, Serrano M.

PLoS One. 2009;4(5):e5475. doi: 10.1371/journal.pone.0005475.

2.

Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis.

Garrison SP, Jeffers JR, Yang C, Nilsson JA, Hall MA, Rehg JE, Yue W, Yu J, Zhang L, Onciu M, Sample JT, Cleveland JL, Zambetti GP.

Mol Cell Biol. 2008 Sep;28(17):5391-402. doi: 10.1128/MCB.00907-07.

3.

The ataxia telangiectasia-mutated target site Ser18 is required for p53-mediated tumor suppression.

Armata HL, Garlick DS, Sluss HK.

Cancer Res. 2007 Dec 15;67(24):11696-703.

4.

DNA damage signalling guards against activated oncogenes and tumour progression.

Bartek J, Bartkova J, Lukas J.

Oncogene. 2007 Dec 10;26(56):7773-9. Review.

PMID:
18066090
5.

Atm deficiency affects both apoptosis and proliferation to augment Myc-induced lymphomagenesis.

Maclean KH, Kastan MB, Cleveland JL.

Mol Cancer Res. 2007 Jul;5(7):705-11.

6.

Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.

Shreeram S, Hee WK, Demidov ON, Kek C, Yamaguchi H, Fornace AJ Jr, Anderson CW, Appella E, Bulavin DV.

J Exp Med. 2006 Dec 25;203(13):2793-9.

7.

ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.

Pusapati RV, Rounbehler RJ, Hong S, Powers JT, Yan M, Kiguchi K, McArthur MJ, Wong PK, Johnson DG.

Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1446-51.

8.

The p53 pathway: positive and negative feedback loops.

Harris SL, Levine AJ.

Oncogene. 2005 Apr 18;24(17):2899-908. Review.

PMID:
15838523
9.

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.

Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, Venere M, Ditullio RA Jr, Kastrinakis NG, Levy B, Kletsas D, Yoneta A, Herlyn M, Kittas C, Halazonetis TD.

Nature. 2005 Apr 14;434(7035):907-13.

PMID:
15829965
10.

Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development.

Eischen CM, Alt JR, Wang P.

Oncogene. 2004 Nov 25;23(55):8931-40.

PMID:
15467748
11.

Phosphorylation of serine 18 regulates distinct p53 functions in mice.

Sluss HK, Armata H, Gallant J, Jones SN.

Mol Cell Biol. 2004 Feb;24(3):976-84.

12.

Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth.

Steinman HA, Sluss HK, Sands AT, Pihan G, Jones SN.

Oncogene. 2004 Jan 8;23(1):303-6.

PMID:
14712235
13.

MDM2, an introduction.

Iwakuma T, Lozano G.

Mol Cancer Res. 2003 Dec;1(14):993-1000. Review.

14.

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways.

Jeffers JR, Parganas E, Lee Y, Yang C, Wang J, Brennan J, MacLean KH, Han J, Chittenden T, Ihle JN, McKinnon PJ, Cleveland JL, Zambetti GP.

Cancer Cell. 2003 Oct;4(4):321-8.

15.

Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis.

Alt JR, Greiner TC, Cleveland JL, Eischen CM.

EMBO J. 2003 Mar 17;22(6):1442-50.

16.

Live or let die: the cell's response to p53.

Vousden KH, Lu X.

Nat Rev Cancer. 2002 Aug;2(8):594-604. Review. No abstract available.

PMID:
12154352
17.

Assessing TP53 status in human tumours to evaluate clinical outcome.

Soussi T, BĂ©roud C.

Nat Rev Cancer. 2001 Dec;1(3):233-40. Review.

PMID:
11902578
18.

Post-translational modifications and activation of p53 by genotoxic stresses.

Appella E, Anderson CW.

Eur J Biochem. 2001 May;268(10):2764-72. Review.

19.

Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage.

Chao C, Saito S, Anderson CW, Appella E, Xu Y.

Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):11936-41.

20.

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

Schmitt CA, McCurrach ME, de Stanchina E, Wallace-Brodeur RR, Lowe SW.

Genes Dev. 1999 Oct 15;13(20):2670-7.

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