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Items: 1 to 20 of 32


Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins.

Zhu S, Gladson CL, White KE, Ding Q, Stewart J Jr, Jin TH, Chapman HA Jr, Olman MA.

Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L97-108. doi: 10.1152/ajplung.90283.2008. Epub 2009 May 1.


Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner.

Ding Q, Gladson CL, Wu H, Hayasaka H, Olman MA.

J Biol Chem. 2008 Oct 3;283(40):26839-49. doi: 10.1074/jbc.M803645200. Epub 2008 Jul 31.


FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts.

Iwanicki MP, Vomastek T, Tilghman RW, Martin KH, Banerjee J, Wedegaertner PB, Parsons JT.

J Cell Sci. 2008 Mar 15;121(Pt 6):895-905. doi: 10.1242/jcs.020941. Epub 2008 Feb 26.


New concepts regarding focal adhesion kinase promotion of cell migration and proliferation.

Cox BD, Natarajan M, Stettner MR, Gladson CL.

J Cell Biochem. 2006 Sep 1;99(1):35-52. Review.


p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain.

Ding Q, Grammer JR, Nelson MA, Guan JL, Stewart JE Jr, Gladson CL.

J Biol Chem. 2005 Feb 25;280(8):6802-15. Epub 2004 Nov 19.


Multiple connections link FAK to cell motility and invasion.

Schlaepfer DD, Mitra SK.

Curr Opin Genet Dev. 2004 Feb;14(1):92-101. Review.


Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells.

Hecker TP, Ding Q, Rege TA, Hanks SK, Gladson CL.

Oncogene. 2004 May 13;23(22):3962-71.


Disorders of lung matrix remodeling.

Chapman HA.

J Clin Invest. 2004 Jan;113(2):148-57. Review.


The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged.

Ding Q, Stewart J Jr, Olman MA, Klobe MR, Gladson CL.

J Biol Chem. 2003 Oct 10;278(41):39882-91. Epub 2003 Jul 24.


Integrin alpha4beta1 regulates migration across basement membranes by lung fibroblasts: a role for phosphatase and tensin homologue deleted on chromosome 10.

White ES, Thannickal VJ, Carskadon SL, Dickie EG, Livant DL, Markwart S, Toews GB, Arenberg DA.

Am J Respir Crit Care Med. 2003 Aug 15;168(4):436-42. Epub 2003 Jun 5.


Direct interaction of focal adhesion kinase with p190RhoGEF.

Zhai J, Lin H, Nie Z, Wu J, CaƱete-Soler R, Schlaepfer WW, Schlaepfer DD.

J Biol Chem. 2003 Jul 4;278(27):24865-73. Epub 2003 Apr 17.


Focal adhesion kinase: the first ten years.

Parsons JT.

J Cell Sci. 2003 Apr 15;116(Pt 8):1409-16. Review.


FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth.

Hauck CR, Hsia DA, Puente XS, Cheresh DA, Schlaepfer DD.

EMBO J. 2002 Dec 2;21(23):6289-302.


Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortality.

King TE Jr, Schwarz MI, Brown K, Tooze JA, Colby TV, Waldron JA Jr, Flint A, Thurlbeck W, Cherniack RM.

Am J Respir Crit Care Med. 2001 Sep 15;164(6):1025-32.


Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells.

Taylor JM, Mack CP, Nolan K, Regan CP, Owens GK, Parsons JT.

Mol Cell Biol. 2001 Mar;21(5):1565-72.


p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo.

Wang D, Grammer JR, Cobbs CS, Stewart JE Jr, Liu Z, Rhoden R, Hecker TP, Ding Q, Gladson CL.

J Cell Sci. 2000 Dec;113 Pt 23:4221-30.


FAK integrates growth-factor and integrin signals to promote cell migration.

Sieg DJ, Hauck CR, Ilic D, Klingbeil CK, Schaefer E, Damsky CH, Schlaepfer DD.

Nat Cell Biol. 2000 May;2(5):249-56.


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