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Items: 1 to 20 of 65

1.

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

Puxeddu E, Uhart M, Li CC, Ahmad F, Pacheco-Rodriguez G, Manganiello VC, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6158-63. doi: 10.1073/pnas.0901558106. Epub 2009 Mar 30.

2.

ABCD of the phosphodiesterase family: interaction and differential activity in COPD.

Halpin DM.

Int J Chron Obstruct Pulmon Dis. 2008;3(4):543-61. Review.

3.

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

Rogers CS, Stoltz DA, Meyerholz DK, Ostedgaard LS, Rokhlina T, Taft PJ, Rogan MP, Pezzulo AA, Karp PH, Itani OA, Kabel AC, Wohlford-Lenane CL, Davis GJ, Hanfland RA, Smith TL, Samuel M, Wax D, Murphy CN, Rieke A, Whitworth K, Uc A, Starner TD, Brogden KA, Shilyansky J, McCray PB Jr, Zabner J, Prather RS, Welsh MJ.

Science. 2008 Sep 26;321(5897):1837-41. doi: 10.1126/science.1163600.

4.

Substance P stimulates CFTR-dependent fluid secretion by mouse tracheal submucosal glands.

Ianowski JP, Choi JY, Wine JJ, Hanrahan JW.

Pflugers Arch. 2008 Nov;457(2):529-37. doi: 10.1007/s00424-008-0527-0. Epub 2008 May 29.

PMID:
18509672
5.

CFTR function and prospects for therapy.

Riordan JR.

Annu Rev Biochem. 2008;77:701-26. doi: 10.1146/annurev.biochem.75.103004.142532. Review.

PMID:
18304008
6.

Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia.

Li C, Krishnamurthy PC, Penmatsa H, Marrs KL, Wang XQ, Zaccolo M, Jalink K, Li M, Nelson DJ, Schuetz JD, Naren AP.

Cell. 2007 Nov 30;131(5):940-51.

7.

Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis.

Choi JY, Joo NS, Krouse ME, Wu JV, Robbins RC, Ianowski JP, Hanrahan JW, Wine JJ.

J Clin Invest. 2007 Oct;117(10):3118-27.

9.
10.

Re-discovering PDE3 inhibitors--new opportunities for a long neglected target.

Thompson PE, Manganiello V, Degerman E.

Curr Top Med Chem. 2007;7(4):421-36. Review.

PMID:
17305583
11.

Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors.

Lee JH, Richter W, Namkung W, Kim KH, Kim E, Conti M, Lee MG.

J Biol Chem. 2007 Apr 6;282(14):10414-22. Epub 2007 Jan 23.

12.

Review of current and investigational pharmacologic agents for acute heart failure syndromes.

Shin DD, Brandimarte F, De Luca L, Sabbah HN, Fonarow GC, Filippatos G, Komajda M, Gheorghiade M.

Am J Cardiol. 2007 Jan 22;99(2A):4A-23A. Epub 2006 Nov 27. Review.

PMID:
17239703
13.

CFTR surface expression and chloride currents are decreased by inhibitors of N-WASP and actin polymerization.

Ganeshan R, Nowotarski K, Di A, Nelson DJ, Kirk KL.

Biochim Biophys Acta. 2007 Feb;1773(2):192-200. Epub 2006 Oct 3.

14.

Methods to measure the lateral diffusion of membrane lipids and proteins.

Chen Y, Lagerholm BC, Yang B, Jacobson K.

Methods. 2006 Jun;39(2):147-53. Review.

PMID:
16846741
15.

AKAP signaling complexes: getting to the heart of the matter.

McConnachie G, Langeberg LK, Scott JD.

Trends Mol Med. 2006 Jul;12(7):317-23. Epub 2006 Jun 30. Review.

PMID:
16809066
16.

Membrane lateral diffusion and capture of CFTR within transient confinement zones.

Bates IR, H├ębert B, Luo Y, Liao J, Bachir AI, Kolin DL, Wiseman PW, Hanrahan JW.

Biophys J. 2006 Aug 1;91(3):1046-58. Epub 2006 May 19.

17.

The where's and when's of kinase anchoring.

Smith FD, Langeberg LK, Scott JD.

Trends Biochem Sci. 2006 Jun;31(6):316-23. Epub 2006 May 11. Review.

PMID:
16690317
18.

Phosphodiesterases and compartmentalized cAMP signalling in the heart.

Zaccolo M.

Eur J Cell Biol. 2006 Jul;85(7):693-7. Epub 2006 Feb 7. Review.

PMID:
16466668
19.

Phosphodiesterase inhibitors in airways disease.

Fan Chung K.

Eur J Pharmacol. 2006 Mar 8;533(1-3):110-7. Epub 2006 Feb 2. Review.

PMID:
16458289
20.

Phosphodiesterase-4: selective and dual-specificity inhibitors for the therapy of chronic obstructive pulmonary disease.

Giembycz MA.

Proc Am Thorac Soc. 2005;2(4):326-33; discussion 340-1. Review.

PMID:
16267357

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