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Items: 1 to 20 of 73

1.

Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease.

Ferruzzi MG, Lobo JK, Janle EM, Cooper B, Simon JE, Wu QL, Welch C, Ho L, Weaver C, Pasinetti GM.

J Alzheimers Dis. 2009;18(1):113-24. doi: 10.3233/JAD-2009-1135.

2.

All-you-can-eat: autophagy in neurodegeneration and neuroprotection.

Jaeger PA, Wyss-Coray T.

Mol Neurodegener. 2009 Apr 6;4:16. doi: 10.1186/1750-1326-4-16.

3.

PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure.

Cantó C, Auwerx J.

Curr Opin Lipidol. 2009 Apr;20(2):98-105. doi: 10.1097/MOL.0b013e328328d0a4. Review.

4.

The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged.

Craft S.

Arch Neurol. 2009 Mar;66(3):300-5. doi: 10.1001/archneurol.2009.27. Review.

5.

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans.

Greer EL, Brunet A.

Aging Cell. 2009 Apr;8(2):113-27. doi: 10.1111/j.1474-9726.2009.00459.x. Epub 2009 Feb 23.

6.

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.

Chen Y, Zhou K, Wang R, Liu Y, Kwak YD, Ma T, Thompson RC, Zhao Y, Smith L, Gasparini L, Luo Z, Xu H, Liao FF.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3907-12. doi: 10.1073/pnas.0807991106. Epub 2009 Feb 23.

7.

Mutant presenilin 1 increases the expression and activity of BACE1.

Giliberto L, Borghi R, Piccini A, Mangerini R, Sorbi S, Cirmena G, Garuti A, Ghetti B, Tagliavini F, Mughal MR, Mattson MP, Zhu X, Wang X, Guglielmotto M, Tamagno E, Tabaton M.

J Biol Chem. 2009 Apr 3;284(14):9027-38. doi: 10.1074/jbc.M805685200. Epub 2009 Feb 5.

8.

Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells.

Greco SJ, Sarkar S, Johnston JM, Tezapsidis N.

Biochem Biophys Res Commun. 2009 Feb 27;380(1):98-104. doi: 10.1016/j.bbrc.2009.01.041. Epub 2009 Jan 21.

9.

Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's disease-type neuropathology and cognitive deterioration.

Ho L, Chen LH, Wang J, Zhao W, Talcott ST, Ono K, Teplow D, Humala N, Cheng A, Percival SS, Ferruzzi M, Janle E, Dickstein DL, Pasinetti GM.

J Alzheimers Dis. 2009;16(1):59-72. doi: 10.3233/JAD-2009-0916.

10.

Therapeutic potential of resveratrol in Alzheimer's disease.

Vingtdeux V, Dreses-Werringloer U, Zhao H, Davies P, Marambaud P.

BMC Neurosci. 2008 Dec 3;9 Suppl 2:S6. doi: 10.1186/1471-2202-9-S2-S6. Review.

11.

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation.

Feige JN, Lagouge M, Canto C, Strehle A, Houten SM, Milne JC, Lambert PD, Mataki C, Elliott PJ, Auwerx J.

Cell Metab. 2008 Nov;8(5):347-58. doi: 10.1016/j.cmet.2008.08.017. Erratum in: Cell Metab. 2009 Feb;9(2):210.

12.

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease.

Karuppagounder SS, Pinto JT, Xu H, Chen HL, Beal MF, Gibson GE.

Neurochem Int. 2009 Feb;54(2):111-8. doi: 10.1016/j.neuint.2008.10.008. Epub 2008 Nov 8.

13.

The regulation of AMP-activated protein kinase by upstream kinases.

Carling D, Sanders MJ, Woods A.

Int J Obes (Lond). 2008 Sep;32 Suppl 4:S55-9. doi: 10.1038/ijo.2008.124. Review.

PMID:
18719600
14.

Amyloid-beta peptide degradation in cell cultures by mycoplasma contaminants.

Zhao H, Dreses-Werringloer U, Davies P, Marambaud P.

BMC Res Notes. 2008 Jun 30;1:38. doi: 10.1186/1756-0500-1-38.

15.

SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation.

Lan F, Cacicedo JM, Ruderman N, Ido Y.

J Biol Chem. 2008 Oct 10;283(41):27628-35. doi: 10.1074/jbc.M805711200. Epub 2008 Aug 7.

16.

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.

Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA, Csiszar A, Ikeno Y, Le Couteur D, Elliott PJ, Becker KG, Navas P, Ingram DK, Wolf NS, Ungvari Z, Sinclair DA, de Cabo R.

Cell Metab. 2008 Aug;8(2):157-68. doi: 10.1016/j.cmet.2008.06.011. Epub 2008 Jul 3.

17.

A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk.

Dreses-Werringloer U, Lambert JC, Vingtdeux V, Zhao H, Vais H, Siebert A, Jain A, Koppel J, Rovelet-Lecrux A, Hannequin D, Pasquier F, Galimberti D, Scarpini E, Mann D, Lendon C, Campion D, Amouyel P, Davies P, Foskett JK, Campagne F, Marambaud P.

Cell. 2008 Jun 27;133(7):1149-61. doi: 10.1016/j.cell.2008.05.048.

18.

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.

Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T.

J Clin Invest. 2008 Jun;118(6):2190-9. doi: 10.1172/JCI33585.

19.

SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase.

Hou X, Xu S, Maitland-Toolan KA, Sato K, Jiang B, Ido Y, Lan F, Walsh K, Wierzbicki M, Verbeuren TJ, Cohen RA, Zang M.

J Biol Chem. 2008 Jul 18;283(29):20015-26. doi: 10.1074/jbc.M802187200. Epub 2008 May 14.

20.

Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms.

Saeedi R, Parsons HL, Wambolt RB, Paulson K, Sharma V, Dyck JR, Brownsey RW, Allard MF.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2497-506. doi: 10.1152/ajpheart.00873.2007. Epub 2008 Mar 28.

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