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Items: 1 to 20 of 32

1.

Identification of a physiological E2 module for the human anaphase-promoting complex.

Williamson A, Wickliffe KE, Mellone BG, Song L, Karpen GH, Rape M.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18213-8. doi: 10.1073/pnas.0907887106. Epub 2009 Oct 12.

2.

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit.

Garnett MJ, Mansfeld J, Godwin C, Matsusaka T, Wu J, Russell P, Pines J, Venkitaraman AR.

Nat Cell Biol. 2009 Nov;11(11):1363-9. doi: 10.1038/ncb1983. Epub 2009 Oct 11.

3.

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.

Alexandru G, Graumann J, Smith GT, Kolawa NJ, Fang R, Deshaies RJ.

Cell. 2008 Sep 5;134(5):804-16. doi: 10.1016/j.cell.2008.06.048.

4.

The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.

Summers MK, Pan B, Mukhyala K, Jackson PK.

Mol Cell. 2008 Aug 22;31(4):544-56. doi: 10.1016/j.molcel.2008.07.014.

5.

Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series.

Ikeda F, Dikic I.

EMBO Rep. 2008 Jun;9(6):536-42. doi: 10.1038/embor.2008.93. Review.

6.

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex.

Jin L, Williamson A, Banerjee S, Philipp I, Rape M.

Cell. 2008 May 16;133(4):653-65. doi: 10.1016/j.cell.2008.04.012.

8.

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.

Christensen DE, Brzovic PS, Klevit RE.

Nat Struct Mol Biol. 2007 Oct;14(10):941-8. Epub 2007 Sep 16.

PMID:
17873885
9.

The ubiquitin-conjugating enzyme E2-EPF is overexpressed in primary breast cancer and modulates sensitivity to topoisomerase II inhibition.

Tedesco D, Zhang J, Trinh L, Lalehzadeh G, Meisner R, Yamaguchi KD, Ruderman DL, Dinter H, Zajchowski DA.

Neoplasia. 2007 Jul;9(7):601-13.

10.

Global changes to the ubiquitin system in Huntington's disease.

Bennett EJ, Shaler TA, Woodman B, Ryu KY, Zaitseva TS, Becker CH, Bates GP, Schulman H, Kopito RR.

Nature. 2007 Aug 9;448(7154):704-8.

PMID:
17687326
11.

Sequential E2s drive polyubiquitin chain assembly on APC targets.

Rodrigo-Brenni MC, Morgan DO.

Cell. 2007 Jul 13;130(1):127-39.

12.

Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation.

Reddy SK, Rape M, Margansky WA, Kirschner MW.

Nature. 2007 Apr 19;446(7138):921-5.

PMID:
17443186
13.

Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint.

Braunstein I, Miniowitz S, Moshe Y, Hershko A.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):4870-5. Epub 2007 Mar 13.

14.

The anaphase promoting complex/cyclosome: a machine designed to destroy.

Peters JM.

Nat Rev Mol Cell Biol. 2006 Sep;7(9):644-56. Epub 2006 Aug 9. Review.

PMID:
16896351
15.

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology.

Kirkpatrick DS, Hathaway NA, Hanna J, Elsasser S, Rush J, Finley D, King RW, Gygi SP.

Nat Cell Biol. 2006 Jul;8(7):700-10. Epub 2006 Jun 25. Erratum in: Nat Cell Biol. 2006 Aug;8(8):896.

PMID:
16799550
16.
17.
18.

Ubiquitin: structures, functions, mechanisms.

Pickart CM, Eddins MJ.

Biochim Biophys Acta. 2004 Nov 29;1695(1-3):55-72. Review.

19.

Polyubiquitin chains: polymeric protein signals.

Pickart CM, Fushman D.

Curr Opin Chem Biol. 2004 Dec;8(6):610-6. Review.

PMID:
15556404
20.

A proteomics approach to understanding protein ubiquitination.

Peng J, Schwartz D, Elias JE, Thoreen CC, Cheng D, Marsischky G, Roelofs J, Finley D, Gygi SP.

Nat Biotechnol. 2003 Aug;21(8):921-6. Epub 2003 Jul 20.

PMID:
12872131

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