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Items: 1 to 20 of 25

1.

Assays for chemotaxis and chemoattractant-stimulated TorC2 activation and PKB substrate phosphorylation in Dictyostelium.

Kamimura Y, Tang M, Devreotes P.

Methods Mol Biol. 2009;571:255-70. doi: 10.1007/978-1-60761-198-1_17.

2.

Chemotaxis: finding the way forward with Dictyostelium.

King JS, Insall RH.

Trends Cell Biol. 2009 Oct;19(10):523-30. doi: 10.1016/j.tcb.2009.07.004. Epub 2009 Sep 3. Review.

PMID:
19733079
3.

Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways.

Bayascas JR.

Cell Cycle. 2008 Oct;7(19):2978-82. Epub 2008 Oct 18. Review.

PMID:
18802401
4.

Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration.

Inoue T, Meyer T.

PLoS One. 2008 Aug 27;3(8):e3068. doi: 10.1371/journal.pone.0003068.

5.

PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

Kamimura Y, Xiong Y, Iglesias PA, Hoeller O, Bolourani P, Devreotes PN.

Curr Biol. 2008 Jul 22;18(14):1034-43. doi: 10.1016/j.cub.2008.06.068.

6.

Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.

Bayascas JR, Wullschleger S, Sakamoto K, García-Martínez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR.

Mol Cell Biol. 2008 May;28(10):3258-72. doi: 10.1128/MCB.02032-07. Epub 2008 Mar 17.

7.

Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis.

van Haastert PJ, Keizer-Gunnink I, Kortholt A.

J Cell Biol. 2007 Jun 4;177(5):809-16. Epub 2007 May 29.

8.

PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.

Chen L, Iijima M, Tang M, Landree MA, Huang YE, Xiong Y, Iglesias PA, Devreotes PN.

Dev Cell. 2007 Apr;12(4):603-14.

9.

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1.

Nishio M, Watanabe K, Sasaki J, Taya C, Takasuga S, Iizuka R, Balla T, Yamazaki M, Watanabe H, Itoh R, Kuroda S, Horie Y, Förster I, Mak TW, Yonekawa H, Penninger JM, Kanaho Y, Suzuki A, Sasaki T.

Nat Cell Biol. 2007 Jan;9(1):36-44. Epub 2006 Dec 17.

PMID:
17173042
10.

PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.

Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L.

Nat Cell Biol. 2007 Jan;9(1):86-91. Epub 2006 Dec 17.

PMID:
17173040
11.

Navigating signaling networks: chemotaxis in Dictyostelium discoideum.

Franca-Koh J, Kamimura Y, Devreotes P.

Curr Opin Genet Dev. 2006 Aug;16(4):333-8. Epub 2006 Jun 19. Review.

PMID:
16782326
12.

TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.

Lee S, Comer FI, Sasaki A, McLeod IX, Duong Y, Okumura K, Yates JR 3rd, Parent CA, Firtel RA.

Mol Biol Cell. 2005 Oct;16(10):4572-83. Epub 2005 Aug 3.

13.

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Sarbassov DD, Guertin DA, Ali SM, Sabatini DM.

Science. 2005 Feb 18;307(5712):1098-101.

14.

PDK1, the master regulator of AGC kinase signal transduction.

Mora A, Komander D, van Aalten DM, Alessi DR.

Semin Cell Dev Biol. 2004 Apr;15(2):161-70. Review.

PMID:
15209375
15.

Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells.

Huang YE, Iijima M, Parent CA, Funamoto S, Firtel RA, Devreotes P.

Mol Biol Cell. 2003 May;14(5):1913-22. Epub 2003 Feb 6.

16.

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis.

Funamoto S, Meili R, Lee S, Parry L, Firtel RA.

Cell. 2002 May 31;109(5):611-23.

17.

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

Iijima M, Devreotes P.

Cell. 2002 May 31;109(5):599-610.

18.

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

Biondi RM, Kieloch A, Currie RA, Deak M, Alessi DR.

EMBO J. 2001 Aug 15;20(16):4380-90.

19.
20.

A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium.

Meili R, Ellsworth C, Firtel RA.

Curr Biol. 2000 Jun 15;10(12):708-17.

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