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Items: 1 to 20 of 57

1.

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.

Hanker AB, Mitin N, Wilder RS, Henske EP, Tamanoi F, Cox AD, Der CJ.

Oncogene. 2010 Jan 21;29(3):380-91. doi: 10.1038/onc.2009.336. Epub 2009 Oct 19.

2.

The Vam6 GEF controls TORC1 by activating the EGO complex.

Binda M, Péli-Gulli MP, Bonfils G, Panchaud N, Urban J, Sturgill TW, Loewith R, De Virgilio C.

Mol Cell. 2009 Sep 11;35(5):563-73. doi: 10.1016/j.molcel.2009.06.033.

3.

Intracellular sterol dynamics.

Mesmin B, Maxfield FR.

Biochim Biophys Acta. 2009 Jul;1791(7):636-45. doi: 10.1016/j.bbalip.2009.03.002. Epub 2009 Mar 12. Review.

4.

Rab7 regulates late endocytic trafficking downstream of multivesicular body biogenesis and cargo sequestration.

Vanlandingham PA, Ceresa BP.

J Biol Chem. 2009 May 1;284(18):12110-24. doi: 10.1074/jbc.M809277200. Epub 2009 Mar 5.

5.

hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells.

Yan Y, Flinn RJ, Wu H, Schnur RS, Backer JM.

Biochem J. 2009 Feb 1;417(3):747-55. doi: 10.1042/BJ20081865.

6.

Lysobisphosphatidic acid controls endosomal cholesterol levels.

Chevallier J, Chamoun Z, Jiang G, Prestwich G, Sakai N, Matile S, Parton RG, Gruenberg J.

J Biol Chem. 2008 Oct 10;283(41):27871-80. doi: 10.1074/jbc.M801463200. Epub 2008 Jul 21.

7.

Regulation of TORC1 by Rag GTPases in nutrient response.

Kim E, Goraksha-Hicks P, Li L, Neufeld TP, Guan KL.

Nat Cell Biol. 2008 Aug;10(8):935-45. doi: 10.1038/ncb1753. Epub 2008 Jul 6.

8.

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.

Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM.

Science. 2008 Jun 13;320(5882):1496-501. doi: 10.1126/science.1157535. Epub 2008 May 22.

9.

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance.

Tremblay F, Brûlé S, Hee Um S, Li Y, Masuda K, Roden M, Sun XJ, Krebs M, Polakiewicz RD, Thomas G, Marette A.

Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14056-61. Epub 2007 Aug 20.

10.

Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae.

Zurita-Martinez SA, Puria R, Pan X, Boeke JD, Cardenas ME.

Genetics. 2007 Aug;176(4):2139-50. Epub 2007 Jun 11.

11.

Targeting and localized signalling by small GTPases.

ten Klooster JP, Hordijk PL.

Biol Cell. 2007 Jan;99(1):1-12. Review.

PMID:
17155934
12.

mTOR, translation initiation and cancer.

Mamane Y, Petroulakis E, LeBacquer O, Sonenberg N.

Oncogene. 2006 Oct 16;25(48):6416-22. Review.

PMID:
17041626
13.

Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase.

Avruch J, Hara K, Lin Y, Liu M, Long X, Ortiz-Vega S, Yonezawa K.

Oncogene. 2006 Oct 16;25(48):6361-72. Review.

PMID:
17041622
14.
15.

Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

Um SH, D'Alessio D, Thomas G.

Cell Metab. 2006 Jun;3(6):393-402. Review.

16.
17.

Localization of Rheb to the endomembrane is critical for its signaling function.

Buerger C, DeVries B, Stambolic V.

Biochem Biophys Res Commun. 2006 Jun 9;344(3):869-80. Epub 2006 Apr 19.

PMID:
16631613
18.

TOR signaling in growth and metabolism.

Wullschleger S, Loewith R, Hall MN.

Cell. 2006 Feb 10;124(3):471-84. Review.

19.

Growing roles for the mTOR pathway.

Sarbassov DD, Ali SM, Sabatini DM.

Curr Opin Cell Biol. 2005 Dec;17(6):596-603. Epub 2005 Oct 13. Review.

PMID:
16226444
20.

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

Nobukuni T, Joaquin M, Roccio M, Dann SG, Kim SY, Gulati P, Byfield MP, Backer JM, Natt F, Bos JL, Zwartkruis FJ, Thomas G.

Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14238-43. Epub 2005 Sep 21.

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