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Items: 1 to 20 of 46

1.

Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo.

Daniel JA, Pellegrini M, Lee JH, Paull TT, Feigenbaum L, Nussenzweig A.

J Cell Biol. 2008 Dec 1;183(5):777-83. doi: 10.1083/jcb.200805154.

2.

Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.

Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, Sekiguchi JM, Chang S, Ferguson DO.

Cell. 2008 Oct 3;135(1):85-96. doi: 10.1016/j.cell.2008.08.015.

3.

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks.

Wu L, Luo K, Lou Z, Chen J.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11200-5. doi: 10.1073/pnas.0802885105. Epub 2008 Aug 4.

4.

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage.

Chapman JR, Jackson SP.

EMBO Rep. 2008 Aug;9(8):795-801. doi: 10.1038/embor.2008.103. Epub 2008 Jun 27.

5.

Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin.

Spycher C, Miller ES, Townsend K, Pavic L, Morrice NA, Janscak P, Stewart GS, Stucki M.

J Cell Biol. 2008 Apr 21;181(2):227-40. doi: 10.1083/jcb.200709008. Epub 2008 Apr 14.

6.

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin.

Melander F, Bekker-Jensen S, Falck J, Bartek J, Mailand N, Lukas J.

J Cell Biol. 2008 Apr 21;181(2):213-26. doi: 10.1083/jcb.200708210. Epub 2008 Apr 14.

7.

Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit.

Davis AJ, Yan Z, Martinez B, Mumby MC.

J Biol Chem. 2008 Jun 6;283(23):16104-14. doi: 10.1074/jbc.M710313200. Epub 2008 Apr 8.

8.

Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts.

Asaithamby A, Uematsu N, Chatterjee A, Story MD, Burma S, Chen DJ.

Radiat Res. 2008 Apr;169(4):437-46. doi: 10.1667/RR1165.1.

PMID:
18363429
9.

Ku recruits XLF to DNA double-strand breaks.

Yano K, Morotomi-Yano K, Wang SY, Uematsu N, Lee KJ, Asaithamby A, Weterings E, Chen DJ.

EMBO Rep. 2008 Jan;9(1):91-6. Epub 2007 Dec 7.

10.

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.

Huen MS, Grant R, Manke I, Minn K, Yu X, Yaffe MB, Chen J.

Cell. 2007 Nov 30;131(5):901-14. Epub 2007 Nov 20.

11.

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.

Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, Lukas C, Lukas J.

Cell. 2007 Nov 30;131(5):887-900. Epub 2007 Nov 20.

12.

ATMIN defines an NBS1-independent pathway of ATM signalling.

Kanu N, Behrens A.

EMBO J. 2007 Jun 20;26(12):2933-41. Epub 2007 May 24.

13.

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ.

Science. 2007 May 25;316(5828):1160-6.

14.

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair.

Berkovich E, Monnat RJ Jr, Kastan MB.

Nat Cell Biol. 2007 Jun;9(6):683-90. Epub 2007 May 7.

PMID:
17486112
15.

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks.

Uematsu N, Weterings E, Yano K, Morotomi-Yano K, Jakob B, Taucher-Scholz G, Mari PO, van Gent DC, Chen BP, Chen DJ.

J Cell Biol. 2007 Apr 23;177(2):219-29. Epub 2007 Apr 16.

16.

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo.

Pellegrini M, Celeste A, Difilippantonio S, Guo R, Wang W, Feigenbaum L, Nussenzweig A.

Nature. 2006 Sep 14;443(7108):222-5. Epub 2006 Aug 13.

PMID:
16906133
17.

Involvement of novel autophosphorylation sites in ATM activation.

Kozlov SV, Graham ME, Peng C, Chen P, Robinson PJ, Lavin MF.

EMBO J. 2006 Aug 9;25(15):3504-14. Epub 2006 Jul 13.

18.

The ATM-mediated DNA-damage response: taking shape.

Shiloh Y.

Trends Biochem Sci. 2006 Jul;31(7):402-10. Epub 2006 Jun 13.

PMID:
16774833
19.

Sub-nuclear localization of Rad51 in response to DNA damage.

Mladenov E, Anachkova B, Tsaneva I.

Genes Cells. 2006 May;11(5):513-24.

20.

Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

Dupré A, Boyer-Chatenet L, Gautier J.

Nat Struct Mol Biol. 2006 May;13(5):451-7. Epub 2006 Apr 23.

PMID:
16622404

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