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Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis.

Wong SY, Seol AD, So PL, Ermilov AN, Bichakjian CK, Epstein EH Jr, Dlugosz AA, Reiter JF.

Nat Med. 2009 Sep;15(9):1055-61. doi: 10.1038/nm.2011. Epub 2009 Aug 23.


Dual and opposing roles of primary cilia in medulloblastoma development.

Han YG, Kim HJ, Dlugosz AA, Ellison DW, Gilbertson RJ, Alvarez-Buylla A.

Nat Med. 2009 Sep;15(9):1062-5. doi: 10.1038/nm.2020. Epub 2009 Aug 23.


Control of centriole length by CPAP and CP110.

Schmidt TI, Kleylein-Sohn J, Westendorf J, Le Clech M, Lavoie SB, Stierhof YD, Nigg EA.

Curr Biol. 2009 Jun 23;19(12):1005-11. doi: 10.1016/j.cub.2009.05.016. Epub 2009 May 28.


Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography.

Lacomble S, Vaughan S, Gadelha C, Morphew MK, Shaw MK, McIntosh JR, Gull K.

J Cell Sci. 2009 Apr 15;122(Pt 8):1081-90. doi: 10.1242/jcs.045740. Epub 2009 Mar 19.


Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia.

Seeley ES, Carrière C, Goetze T, Longnecker DS, Korc M.

Cancer Res. 2009 Jan 15;69(2):422-30. doi: 10.1158/0008-5472.CAN-08-1290.


Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control.

Keller LC, Geimer S, Romijn E, Yates J 3rd, Zamora I, Marshall WF.

Mol Biol Cell. 2009 Feb;20(4):1150-66. doi: 10.1091/mbc.E08-06-0619. Epub 2008 Dec 24.


CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290.

Gorden NT, Arts HH, Parisi MA, Coene KL, Letteboer SJ, van Beersum SE, Mans DA, Hikida A, Eckert M, Knutzen D, Alswaid AF, Ozyurek H, Dibooglu S, Otto EA, Liu Y, Davis EE, Hutter CM, Bammler TK, Farin FM, Dorschner M, Topçu M, Zackai EH, Rosenthal P, Owens KN, Katsanis N, Vincent JB, Hildebrandt F, Rubel EW, Raible DW, Knoers NV, Chance PF, Roepman R, Moens CB, Glass IA, Doherty D.

Am J Hum Genet. 2008 Nov;83(5):559-71. doi: 10.1016/j.ajhg.2008.10.002. Epub 2008 Oct 23.


Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain.

Gorivodsky M, Mukhopadhyay M, Wilsch-Braeuninger M, Phillips M, Teufel A, Kim C, Malik N, Huttner W, Westphal H.

Dev Biol. 2009 Jan 1;325(1):24-32. doi: 10.1016/j.ydbio.2008.09.019. Epub 2008 Sep 26.


Electron tomography study of isolated human centrioles.

Ibrahim R, Messaoudi C, Chichon FJ, Celati C, Marco S.

Microsc Res Tech. 2009 Jan;72(1):42-8. doi: 10.1002/jemt.20637.


CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium.

Kim J, Krishnaswami SR, Gleeson JG.

Hum Mol Genet. 2008 Dec 1;17(23):3796-805. doi: 10.1093/hmg/ddn277. Epub 2008 Sep 4.


Ultrastructural and antigenic properties of neural stem cells and their progeny in adult rat subventricular zone.

Danilov AI, Gomes-Leal W, Ahlenius H, Kokaia Z, Carlemalm E, Lindvall O.

Glia. 2009 Jan 15;57(2):136-52. doi: 10.1002/glia.20741.


CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary disease.

Tsang WY, Bossard C, Khanna H, Peränen J, Swaroop A, Malhotra V, Dynlacht BD.

Dev Cell. 2008 Aug;15(2):187-97. doi: 10.1016/j.devcel.2008.07.004.


Beta-arrestin-mediated localization of smoothened to the primary cilium.

Kovacs JJ, Whalen EJ, Liu R, Xiao K, Kim J, Chen M, Wang J, Chen W, Lefkowitz RJ.

Science. 2008 Jun 27;320(5884):1777-81. doi: 10.1126/science.1157983. Epub 2008 May 22.


Cell cycle-dependent ciliogenesis and cancer.

Plotnikova OV, Golemis EA, Pugacheva EN.

Cancer Res. 2008 Apr 1;68(7):2058-61. doi: 10.1158/0008-5472.CAN-07-5838. Review.


Molecular dissection of ODF2/Cenexin revealed a short stretch of amino acids necessary for targeting to the centrosome and the primary cilium.

Hüber D, Geisler S, Monecke S, Hoyer-Fender S.

Eur J Cell Biol. 2008 Mar;87(3):137-46. doi: 10.1016/j.ejcb.2007.10.004. Epub 2008 Jan 2.


Cilia biology: stop overeating now!

Satir P.

Curr Biol. 2007 Nov 20;17(22):R963-5. Review.


Intraflagellar transport: from molecular characterisation to mechanism.

Blacque OE, Cevik S, Kaplan OI.

Front Biosci. 2008 Jan 1;13:2633-52. Review.


Persistent use of "false" cell lines.

Lacroix M.

Int J Cancer. 2008 Jan 1;122(1):1-4. Review.


Cep164, a novel centriole appendage protein required for primary cilium formation.

Graser S, Stierhof YD, Lavoie SB, Gassner OS, Lamla S, Le Clech M, Nigg EA.

J Cell Biol. 2007 Oct 22;179(2):321-30.


Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain.

Bishop GA, Berbari NF, Lewis J, Mykytyn K.

J Comp Neurol. 2007 Dec 10;505(5):562-71.


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