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Items: 1 to 20 of 59

1.

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.

Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X.

J Neurosci. 2009 Jul 15;29(28):9090-103. doi: 10.1523/JNEUROSCI.1357-09.2009.

2.

Alpha-helix targeting reduces amyloid-beta peptide toxicity.

Nerelius C, Sandegren A, Sargsyan H, Raunak R, Leijonmarck H, Chatterjee U, Fisahn A, Imarisio S, Lomas DA, Crowther DC, Strömberg R, Johansson J.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9191-6. doi: 10.1073/pnas.0810364106. Epub 2009 May 20.

3.

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.

Wang X, Su B, Zheng L, Perry G, Smith MA, Zhu X.

J Neurochem. 2009 May;109 Suppl 1:153-9. doi: 10.1111/j.1471-4159.2009.05867.x. Review.

4.

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease.

Reddy PH.

Exp Neurol. 2009 Aug;218(2):286-92. doi: 10.1016/j.expneurol.2009.03.042. Epub 2009 Apr 7. Review.

5.

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury.

Cho DH, Nakamura T, Fang J, Cieplak P, Godzik A, Gu Z, Lipton SA.

Science. 2009 Apr 3;324(5923):102-5. doi: 10.1126/science.1171091.

6.

Distinctive roles of different beta-amyloid 42 aggregates in modulation of synaptic functions.

Chiang HC, Iijima K, Hakker I, Zhong Y.

FASEB J. 2009 Jun;23(6):1969-77. doi: 10.1096/fj.08-121152. Epub 2009 Mar 2.

7.

Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

Macaskill AF, Rinholm JE, Twelvetrees AE, Arancibia-Carcamo IL, Muir J, Fransson A, Aspenstrom P, Attwell D, Kittler JT.

Neuron. 2009 Feb 26;61(4):541-55. doi: 10.1016/j.neuron.2009.01.030.

8.

Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila.

Ling D, Song HJ, Garza D, Neufeld TP, Salvaterra PM.

PLoS One. 2009;4(1):e4201. doi: 10.1371/journal.pone.0004201. Epub 2009 Jan 15.

9.

The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility.

Wang X, Schwarz TL.

Cell. 2009 Jan 9;136(1):163-74. doi: 10.1016/j.cell.2008.11.046.

10.

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase.

Saotome M, Safiulina D, Szabadkai G, Das S, Fransson A, Aspenstrom P, Rizzuto R, Hajnóczky G.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20728-33. doi: 10.1073/pnas.0808953105. Epub 2008 Dec 19.

11.
12.

Mitochondria in neuroplasticity and neurological disorders.

Mattson MP, Gleichmann M, Cheng A.

Neuron. 2008 Dec 10;60(5):748-66. doi: 10.1016/j.neuron.2008.10.010. Review.

13.

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.

Wang X, Su B, Siedlak SL, Moreira PI, Fujioka H, Wang Y, Casadesus G, Zhu X.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19318-23. doi: 10.1073/pnas.0804871105. Epub 2008 Dec 2.

14.

Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology.

Schilling S, Zeitschel U, Hoffmann T, Heiser U, Francke M, Kehlen A, Holzer M, Hutter-Paier B, Prokesch M, Windisch M, Jagla W, Schlenzig D, Lindner C, Rudolph T, Reuter G, Cynis H, Montag D, Demuth HU, Rossner S.

Nat Med. 2008 Oct;14(10):1106-11. doi: 10.1038/nm.1872. Epub 2008 Sep 28.

PMID:
18836460
15.

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease.

Bezprozvanny I, Mattson MP.

Trends Neurosci. 2008 Sep;31(9):454-63. doi: 10.1016/j.tins.2008.06.005. Epub 2008 Jul 31. Review.

16.

Linking calcium to Abeta and Alzheimer's disease.

Green KN, LaFerla FM.

Neuron. 2008 Jul 31;59(2):190-4. doi: 10.1016/j.neuron.2008.07.013. Review.

17.

Animal models of Alzheimer's disease and frontotemporal dementia.

Götz J, Ittner LM.

Nat Rev Neurosci. 2008 Jul;9(7):532-44. doi: 10.1038/nrn2420. Review.

PMID:
18568014
18.

Mitochondrial fragmentation in neurodegeneration.

Knott AB, Perkins G, Schwarzenbacher R, Bossy-Wetzel E.

Nat Rev Neurosci. 2008 Jul;9(7):505-18. doi: 10.1038/nrn2417. Review.

19.
20.

Abeta42 mutants with different aggregation profiles induce distinct pathologies in Drosophila.

Iijima K, Chiang HC, Hearn SA, Hakker I, Gatt A, Shenton C, Granger L, Leung A, Iijima-Ando K, Zhong Y.

PLoS One. 2008 Feb 27;3(2):e1703. doi: 10.1371/journal.pone.0001703.

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