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Items: 1 to 20 of 33

1.

New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase.

Bharate SB, Guo L, Reeves TE, Cerasoli DM, Thompson CM.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5101-4. doi: 10.1016/j.bmcl.2009.07.035. Epub 2009 Jul 10.

2.
4.

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Jun D, Dohnal V, Gunn-Moore F, Opletalova V, Dolezal M, Kuca K.

Bioorg Med Chem. 2007 Nov 1;15(21):6733-41. Epub 2007 Aug 10.

PMID:
17764957
5.

Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX.

Ghanem E, Li Y, Xu C, Raushel FM.

Biochemistry. 2007 Aug 7;46(31):9032-40. Epub 2007 Jul 14.

PMID:
17630782
6.

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M.

Bioorg Med Chem Lett. 2007 Jun 1;17(11):3172-6. Epub 2007 Mar 13.

PMID:
17383875
7.

Current understanding of the application of pyridinium oximes as cholinesterase reactivators in treatment of organophosphate poisoning.

Jokanović M, Stojiljković MP.

Eur J Pharmacol. 2006 Dec 28;553(1-3):10-7. Epub 2006 Oct 11. Review.

PMID:
17109842
8.

Bis-pyridiumaldoxime reactivators connected with CH2O(CH2)n OCH2 linkers between pyridinium rings and their reactivity against VX.

Oh KA, Yang GY, Jun D, Kuca K, Jung YS.

Bioorg Med Chem Lett. 2006 Sep 15;16(18):4852-5. Epub 2006 Jul 7.

PMID:
16828550
9.

Paraoxon-induced ultrastructural growth changes of rat cultured hippocampal cells in neurobasal/B27.

Yousefpour M, Bahrami F, Shahsavan Behboodi B, Khoshbaten A, Asgari A.

Toxicology. 2006 Jan 16;217(2-3):221-7. Epub 2005 Nov 10.

PMID:
16289293
10.
11.

Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents.

Kim TH, Kuca K, Jun D, Jung YS.

Bioorg Med Chem Lett. 2005 Jun 2;15(11):2914-7. Epub 2005 Apr 21.

PMID:
15911280
12.
13.

Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes.

Worek F, Thiermann H, Szinicz L, Eyer P.

Biochem Pharmacol. 2004 Dec 1;68(11):2237-48.

PMID:
15498514
14.

Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase.

Kuca K, Bielavský J, Cabal J, Kassa J.

Bioorg Med Chem Lett. 2003 Oct 20;13(20):3545-7.

PMID:
14505667
16.

[A NEW ESTERASE REACTIVATOR FOR THE TREATMENT OF ALKYLPHOSPHATE POISONINGS].

ERDMANN WD, VON CLARMANN.

Dtsch Med Wochenschr. 1963 Nov 8;88:2201-6. German. No abstract available.

PMID:
14096591
17.

A new and rapid colorimetric determination of acetylcholinesterase activity.

ELLMAN GL, COURTNEY KD, ANDRES V Jr, FEATHER-STONE RM.

Biochem Pharmacol. 1961 Jul;7:88-95. No abstract available.

PMID:
13726518
18.

New potent reactivators of acetocholinesterase inhibited by tetraethyl pyrophosphate.

HOBBIGER F, O'SULLIVAN DG, SADLER PW.

Nature. 1958 Nov 29;182(4648):1498-9. No abstract available.

PMID:
13613304
19.

The reactivation by oximes and hydroxamic acids of cholinesterase inhibited by organo-phosphorus compounds.

CHILDS AF, DAVIES DR, GREEN AL, RUTLAND JP.

Br J Pharmacol Chemother. 1955 Dec;10(4):462-5. No abstract available.

20.

A powerful reactivator of alkylphosphate-inhibited acetylcholinesterase.

WILSON IB, GINSBURG B.

Biochim Biophys Acta. 1955 Sep;18(1):168-70. No abstract available.

PMID:
13260275

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