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CD45-mediated fodrin cleavage during galectin-1 T cell death promotes phagocytic clearance of dying cells.

Pang M, He J, Johnson P, Baum LG.

J Immunol. 2009 Jun 1;182(11):7001-8. doi: 10.4049/jimmunol.0804329.


Galectin-1 tunes TCR binding and signal transduction to regulate CD8 burst size.

Liu SD, Tomassian T, Bruhn KW, Miller JF, Poirier F, Miceli MC.

J Immunol. 2009 May 1;182(9):5283-95. doi: 10.4049/jimmunol.0803811.


Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function.

Motran CC, Molinder KM, Liu SD, Poirier F, Miceli MC.

Eur J Immunol. 2008 Nov;38(11):3015-27. doi: 10.1002/eji.200838295.


CD45 glycosylation controls T-cell life and death.

Earl LA, Baum LG.

Immunol Cell Biol. 2008 Oct;86(7):608-15. doi: 10.1038/icb.2008.46. Epub 2008 Jul 8. Review.


Disruption of thymopoiesis in ST6Gal I-deficient mice.

Marino JH, Tan C, Davis B, Han ES, Hickey M, Naukam R, Taylor A, Miller KS, Van De Wiele CJ, Teague TK.

Glycobiology. 2008 Sep;18(9):719-26. doi: 10.1093/glycob/cwn051. Epub 2008 Jun 5.


Endogenous galectin-1 enforces class I-restricted TCR functional fate decisions in thymocytes.

Liu SD, Whiting CC, Tomassian T, Pang M, Bissel SJ, Baum LG, Mossine VV, Poirier F, Huflejt ME, Miceli MC.

Blood. 2008 Jul 1;112(1):120-30. doi: 10.1182/blood-2007-09-114181. Epub 2008 Mar 6.


Structural features of galectin-9 and galectin-1 that determine distinct T cell death pathways.

Bi S, Earl LA, Jacobs L, Baum LG.

J Biol Chem. 2008 May 2;283(18):12248-58. doi: 10.1074/jbc.M800523200. Epub 2008 Feb 7.


Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens.

Stowell SR, Arthur CM, Mehta P, Slanina KA, Blixt O, Leffler H, Smith DF, Cummings RD.

J Biol Chem. 2008 Apr 11;283(15):10109-23. doi: 10.1074/jbc.M709545200. Epub 2008 Jan 23.


Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells.

Windhagen A, Sönmez D, Hornig-Do HT, Kalinowsky A, Schwinzer R.

Clin Exp Immunol. 2007 Dec;150(3):509-17. Epub 2007 Sep 28.


Why is there so much CD45 on T cells?

Zamoyska R.

Immunity. 2007 Sep;27(3):421-3. Review.


The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.

McNeill L, Salmond RJ, Cooper JC, Carret CK, Cassady-Cain RL, Roche-Molina M, Tandon P, Holmes N, Alexander DR.

Immunity. 2007 Sep;27(3):425-37. Epub 2007 Aug 23.


T-cell activation results in microheterogeneous changes in glycosylation of CD45.

Hernandez JD, Klein J, Van Dyken SJ, Marth JD, Baum LG.

Int Immunol. 2007 Jul;19(7):847-56. Epub 2007 Jul 2.


Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death.

Toscano MA, Bianco GA, Ilarregui JM, Croci DO, Correale J, Hernandez JD, Zwirner NW, Poirier F, Riley EM, Baum LG, Rabinovich GA.

Nat Immunol. 2007 Aug;8(8):825-34. Epub 2007 Jun 24.


Galectin-1 binds different CD43 glycoforms to cluster CD43 and regulate T cell death.

Hernandez JD, Nguyen JT, He J, Wang W, Ardman B, Green JM, Fukuda M, Baum LG.

J Immunol. 2006 Oct 15;177(8):5328-36.


Haploinsufficiency of C2GnT-I glycosyltransferase renders T lymphoma cells resistant to cell death.

Cabrera PV, Amano M, Mitoma J, Chan J, Said J, Fukuda M, Baum LG.

Blood. 2006 Oct 1;108(7):2399-406. Epub 2006 Jun 15.


Combinations of CD45 isoforms are crucial for immune function and disease.

Dawes R, Petrova S, Liu Z, Wraith D, Beverley PC, Tchilian EZ.

J Immunol. 2006 Mar 15;176(6):3417-25.


Central tolerance: learning self-control in the thymus.

Hogquist KA, Baldwin TA, Jameson SC.

Nat Rev Immunol. 2005 Oct;5(10):772-82. Review.


CD45 isoforms in T cell signalling and development.

McNeill L, Cassady RL, Sarkardei S, Cooper JC, Morgan G, Alexander DR.

Immunol Lett. 2004 Mar 29;92(1-2):125-34.


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