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Items: 1 to 20 of 56

1.

Extracellular microfibrils: contextual platforms for TGFbeta and BMP signaling.

Ramirez F, Rifkin DB.

Curr Opin Cell Biol. 2009 Oct;21(5):616-22. doi: 10.1016/j.ceb.2009.05.005. Epub 2009 Jun 12. Review.

2.

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.

Ono RN, Sengle G, Charbonneau NL, Carlberg V, Bächinger HP, Sasaki T, Lee-Arteaga S, Zilberberg L, Rifkin DB, Ramirez F, Chu ML, Sakai LY.

J Biol Chem. 2009 Jun 19;284(25):16872-81. doi: 10.1074/jbc.M809348200. Epub 2009 Apr 6.

3.

Mouse models of cystathionine beta-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia.

Gupta S, Kühnisch J, Mustafa A, Lhotak S, Schlachterman A, Slifker MJ, Klein-Szanto A, High KA, Austin RC, Kruger WD.

FASEB J. 2009 Mar;23(3):883-93. doi: 10.1096/fj.08-120584. Epub 2008 Nov 5.

4.

Fibrillins, fibulins, and matrix-associated glycoprotein modulate the kinetics and morphology of in vitro self-assembly of a recombinant elastin-like polypeptide.

Cirulis JT, Bellingham CM, Davis EC, Hubmacher D, Reinhardt DP, Mecham RP, Keeley FW.

Biochemistry. 2008 Nov 25;47(47):12601-13. doi: 10.1021/bi8005384.

5.

Heparan sulfate regulates fibrillin-1 N- and C-terminal interactions.

Cain SA, Baldwin AK, Mahalingam Y, Raynal B, Jowitt TA, Shuttleworth CA, Couchman JR, Kielty CM.

J Biol Chem. 2008 Oct 3;283(40):27017-27. doi: 10.1074/jbc.M803373200. Epub 2008 Jul 31.

7.

Biogenesis of extracellular microfibrils: Multimerization of the fibrillin-1 C terminus into bead-like structures enables self-assembly.

Hubmacher D, El-Hallous EI, Nelea V, Kaartinen MT, Lee ER, Reinhardt DP.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6548-53. doi: 10.1073/pnas.0706335105. Epub 2008 Apr 30.

8.

Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bächinger HP, Sakai LY.

J Biol Chem. 2008 May 16;283(20):13874-88. doi: 10.1074/jbc.M707820200. Epub 2008 Mar 13.

9.

New insights into elastic fiber assembly.

Wagenseil JE, Mecham RP.

Birth Defects Res C Embryo Today. 2007 Dec;81(4):229-40. doi: 10.1002/bdrc.20111. Review.

PMID:
18228265
10.

Predicting protein homocysteinylation targets based on dihedral strain energy and pKa of cysteines.

Sundaramoorthy E, Maiti S, Brahmachari SK, Sengupta S.

Proteins. 2008 May 15;71(3):1475-83.

PMID:
18076028
11.

Molecular targeting of proteins by L-homocysteine: mechanistic implications for vascular disease.

Glushchenko AV, Jacobsen DW.

Antioxid Redox Signal. 2007 Nov;9(11):1883-98. Review.

12.

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

El-Hallous E, Sasaki T, Hubmacher D, Getie M, Tiedemann K, Brinckmann J, Bätge B, Davis EC, Reinhardt DP.

J Biol Chem. 2007 Mar 23;282(12):8935-46. Epub 2007 Jan 25.

13.

Fibrillins: from biogenesis of microfibrils to signaling functions.

Hubmacher D, Tiedemann K, Reinhardt DP.

Curr Top Dev Biol. 2006;75:93-123. Review.

PMID:
16984811
14.

Elastin defects in the lungs of avian and murine models of homocysteinemia.

Starcher B, Hill CH.

Exp Lung Res. 2005 Nov-Dec;31(9-10):873-85.

PMID:
16684718
15.

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

Carta L, Pereira L, Arteaga-Solis E, Lee-Arteaga SY, Lenart B, Starcher B, Merkel CA, Sukoyan M, Kerkis A, Hazeki N, Keene DR, Sakai LY, Ramirez F.

J Biol Chem. 2006 Mar 24;281(12):8016-23. Epub 2005 Dec 28.

16.

Absence of autoantibodies against correctly folded recombinant fibrillin-1 protein in systemic sclerosis patients.

Brinckmann J, Hunzelmann N, El-Hallous E, Krieg T, Sakai LY, Krengel S, Reinhardt DP.

Arthritis Res Ther. 2005;7(6):R1221-6. Epub 2005 Sep 6.

17.

Structural determinants of cross-linking and hydrophobic domains for self-assembly of elastin-like polypeptides.

Miao M, Cirulis JT, Lee S, Keeley FW.

Biochemistry. 2005 Nov 1;44(43):14367-75.

PMID:
16245953
18.

Modification of the structure and function of fibrillin-1 by homocysteine suggests a potential pathogenetic mechanism in homocystinuria.

Hubmacher D, Tiedemann K, Bartels R, Brinckmann J, Vollbrandt T, Bätge B, Notbohm H, Reinhardt DP.

J Biol Chem. 2005 Oct 14;280(41):34946-55. Epub 2005 Aug 11.

19.

Genetic determinants of plasma total homocysteine.

Gellekink H, den Heijer M, Heil SG, Blom HJ.

Semin Vasc Med. 2005 May;5(2):98-109. Review.

PMID:
16047263
20.

Coacervation is promoted by molecular interactions between the PF2 segment of fibrillin-1 and the domain 4 region of tropoelastin.

Clarke AW, Wise SG, Cain SA, Kielty CM, Weiss AS.

Biochemistry. 2005 Aug 2;44(30):10271-81.

PMID:
16042404

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