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Disease progression in hemodynamically stable patients presenting to the emergency department with sepsis.

Glickman SW, Cairns CB, Otero RM, Woods CW, Tsalik EL, Langley RJ, van Velkinburgh JC, Park LP, Glickman LT, Fowler VG Jr, Kingsmore SF, Rivers EP.

Acad Emerg Med. 2010 Apr;17(4):383-90. doi: 10.1111/j.1553-2712.2010.00664.x.


Clinical impact of a commercially available multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis.

Dierkes C, Ehrenstein B, Siebig S, Linde HJ, Reischl U, Salzberger B.

BMC Infect Dis. 2009 Aug 11;9:126. doi: 10.1186/1471-2334-9-126.


Utility of a commercially available multiplex real-time PCR assay to detect bacterial and fungal pathogens in febrile neutropenia.

von Lilienfeld-Toal M, Lehmann LE, Raadts AD, Hahn-Ast C, Orlopp KS, Marklein G, Purr I, Cook G, Hoeft A, Glasmacher A, Stüber F.

J Clin Microbiol. 2009 Aug;47(8):2405-10. doi: 10.1128/JCM.00491-09.


Diagnosis of bacteremia in whole-blood samples by use of a commercial universal 16S rRNA gene-based PCR and sequence analysis.

Wellinghausen N, Kochem AJ, Disqué C, Mühl H, Gebert S, Winter J, Matten J, Sakka SG.

J Clin Microbiol. 2009 Sep;47(9):2759-65. doi: 10.1128/JCM.00567-09.


Multiplex real-time PCR and blood culture for identification of bloodstream pathogens in patients with suspected sepsis.

Westh H, Lisby G, Breysse F, Böddinghaus B, Chomarat M, Gant V, Goglio A, Raglio A, Schuster H, Stuber F, Wissing H, Hoeft A.

Clin Microbiol Infect. 2009 Jun;15(6):544-51. doi: 10.1111/j.1469-0691.2009.02736.x.


National Hospital Ambulatory Medical Care Survey: 2006 emergency department summary.

Pitts SR, Niska RW, Xu J, Burt CW.

Natl Health Stat Report. 2008 Aug 6;(7):1-38.


The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a meta-analysis.

Jones AE, Brown MD, Trzeciak S, Shapiro NI, Garrett JS, Heffner AC, Kline JA; Emergency Medicine Shock Research Network investigators..

Crit Care Med. 2008 Oct;36(10):2734-9. doi: 10.1097/CCM.0b013e318186f839. Review.


Molecular diagnosis of sepsis in neutropenic patients with haematological malignancies.

Mancini N, Clerici D, Diotti R, Perotti M, Ghidoli N, De Marco D, Pizzorno B, Emrich T, Burioni R, Ciceri F, Clementi M.

J Med Microbiol. 2008 May;57(Pt 5):601-4. doi: 10.1099/jmm.0.47732-0.


Multiplex polymerase chain reaction detection enhancement of bacteremia and fungemia.

Louie RF, Tang Z, Albertson TE, Cohen S, Tran NK, Kost GJ.

Crit Care Med. 2008 May;36(5):1487-92. doi: 10.1097/CCM.0b013e31816f487c.


A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples.

Lehmann LE, Hunfeld KP, Emrich T, Haberhausen G, Wissing H, Hoeft A, Stüber F.

Med Microbiol Immunol. 2008 Sep;197(3):313-24.


Rapid detection and identification of clinically important bacteria by high-resolution melting analysis after broad-range ribosomal RNA real-time PCR.

Cheng JC, Huang CL, Lin CC, Chen CC, Chang YC, Chang SS, Tseng CP.

Clin Chem. 2006 Nov;52(11):1997-2004.


Severe sepsis and septic shock: review of the literature and emergency department management guidelines.

Nguyen HB, Rivers EP, Abrahamian FM, Moran GJ, Abraham E, Trzeciak S, Huang DT, Osborn T, Stevens D, Talan DA; Emergency Department Sepsis Education Program and Strategies to Improve Survival (ED-SEPSIS) Working Group..

Ann Emerg Med. 2006 Jul;48(1):28-54. Review.


Real-time PCR in clinical microbiology: applications for routine laboratory testing.

Espy MJ, Uhl JR, Sloan LM, Buckwalter SP, Jones MF, Vetter EA, Yao JD, Wengenack NL, Rosenblatt JE, Cockerill FR 3rd, Smith TF.

Clin Microbiol Rev. 2006 Jan;19(1):165-256. Review. Erratum in: Clin Microbiol Rev. 2006 Jul;19(3):595.


Time to positivity in Staphylococcus aureus bacteremia: possible correlation with the source and outcome of infection.

Khatib R, Riederer K, Saeed S, Johnson LB, Fakih MG, Sharma M, Tabriz MS, Khosrovaneh A.

Clin Infect Dis. 2005 Sep 1;41(5):594-8.


Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update.

Hollenberg SM, Ahrens TS, Annane D, Astiz ME, Chalfin DB, Dasta JF, Heard SO, Martin C, Napolitano LM, Susla GM, Totaro R, Vincent JL, Zanotti-Cavazzoni S.

Crit Care Med. 2004 Sep;32(9):1928-48. Review.


The epidemiology of sepsis in the United States from 1979 through 2000.

Martin GS, Mannino DM, Eaton S, Moss M.

N Engl J Med. 2003 Apr 17;348(16):1546-54.


Quality control in nucleic acid testing--where do we stand?

Valentine-Thon E.

J Clin Virol. 2002 Dec;25 Suppl 3:S13-21. Review.


Early goal-directed therapy in the treatment of severe sepsis and septic shock.

Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collaborative Group..

N Engl J Med. 2001 Nov 8;345(19):1368-77.


Contamination of catheter-drawn blood cultures.

Everts RJ, Vinson EN, Adholla PO, Reller LB.

J Clin Microbiol. 2001 Sep;39(9):3393-4.

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