Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 122

1.

Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.

Morfini GA, You YM, Pollema SL, Kaminska A, Liu K, Yoshioka K, Björkblom B, Coffey ET, Bagnato C, Han D, Huang CF, Banker G, Pigino G, Brady ST.

Nat Neurosci. 2009 Jul;12(7):864-71. doi: 10.1038/nn.2346. Epub 2009 Jun 14.

2.

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1.

Edgar JM, McLaughlin M, Werner HB, McCulloch MC, Barrie JA, Brown A, Faichney AB, Snaidero N, Nave KA, Griffiths IR.

Glia. 2009 Dec;57(16):1815-24. doi: 10.1002/glia.20893.

PMID:
19459211
3.

Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis.

Landers JE, Melki J, Meininger V, Glass JD, van den Berg LH, van Es MA, Sapp PC, van Vught PW, McKenna-Yasek DM, Blauw HM, Cho TJ, Polak M, Shi L, Wills AM, Broom WJ, Ticozzi N, Silani V, Ozoguz A, Rodriguez-Leyva I, Veldink JH, Ivinson AJ, Saris CG, Hosler BA, Barnes-Nessa A, Couture N, Wokke JH, Kwiatkowski TJ Jr, Ophoff RA, Cronin S, Hardiman O, Diekstra FP, Leigh PN, Shaw CE, Simpson CL, Hansen VK, Powell JF, Corcia P, Salachas F, Heath S, Galan P, Georges F, Horvitz HR, Lathrop M, Purcell S, Al-Chalabi A, Brown RH Jr.

Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9004-9. doi: 10.1073/pnas.0812937106. Epub 2009 May 18.

4.

Microtubule assembly, organization and dynamics in axons and dendrites.

Conde C, Cáceres A.

Nat Rev Neurosci. 2009 May;10(5):319-32. doi: 10.1038/nrn2631. Review.

PMID:
19377501
5.

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta.

Pigino G, Morfini G, Atagi Y, Deshpande A, Yu C, Jungbauer L, LaDu M, Busciglio J, Brady S.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5907-12. doi: 10.1073/pnas.0901229106. Epub 2009 Mar 24.

6.

Synaptic transmission block by presynaptic injection of oligomeric amyloid beta.

Moreno H, Yu E, Pigino G, Hernandez AI, Kim N, Moreira JE, Sugimori M, Llinás RR.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5901-6. doi: 10.1073/pnas.0900944106. Epub 2009 Mar 20.

7.

Rethinking ALS: the FUS about TDP-43.

Lagier-Tourenne C, Cleveland DW.

Cell. 2009 Mar 20;136(6):1001-4. doi: 10.1016/j.cell.2009.03.006. Review.

8.

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.

Kwiatkowski TJ Jr, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, Davis A, Gilchrist J, Kasarskis EJ, Munsat T, Valdmanis P, Rouleau GA, Hosler BA, Cortelli P, de Jong PJ, Yoshinaga Y, Haines JL, Pericak-Vance MA, Yan J, Ticozzi N, Siddique T, McKenna-Yasek D, Sapp PC, Horvitz HR, Landers JE, Brown RH Jr.

Science. 2009 Feb 27;323(5918):1205-8. doi: 10.1126/science.1166066.

9.

DCTN1 mutations in Perry syndrome.

Farrer MJ, Hulihan MM, Kachergus JM, Dächsel JC, Stoessl AJ, Grantier LL, Calne S, Calne DB, Lechevalier B, Chapon F, Tsuboi Y, Yamada T, Gutmann L, Elibol B, Bhatia KP, Wider C, Vilariño-Güell C, Ross OA, Brown LA, Castanedes-Casey M, Dickson DW, Wszolek ZK.

Nat Genet. 2009 Feb;41(2):163-5. doi: 10.1038/ng.293. Epub 2009 Jan 11.

10.

Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin.

Her LS, Goldstein LS.

J Neurosci. 2008 Dec 10;28(50):13662-72. doi: 10.1523/JNEUROSCI.4144-08.2008.

11.

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms.

Salinas S, Proukakis C, Crosby A, Warner TT.

Lancet Neurol. 2008 Dec;7(12):1127-38. doi: 10.1016/S1474-4422(08)70258-8. Review.

PMID:
19007737
12.

Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis.

Rutherford NJ, Zhang YJ, Baker M, Gass JM, Finch NA, Xu YF, Stewart H, Kelley BJ, Kuntz K, Crook RJ, Sreedharan J, Vance C, Sorenson E, Lippa C, Bigio EH, Geschwind DH, Knopman DS, Mitsumoto H, Petersen RC, Cashman NR, Hutton M, Shaw CE, Boylan KB, Boeve B, Graff-Radford NR, Wszolek ZK, Caselli RJ, Dickson DW, Mackenzie IR, Petrucelli L, Rademakers R.

PLoS Genet. 2008 Sep 19;4(9):e1000193. doi: 10.1371/journal.pgen.1000193.

13.

The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.

LaPointe NE, Morfini G, Pigino G, Gaisina IN, Kozikowski AP, Binder LI, Brady ST.

J Neurosci Res. 2009 Feb;87(2):440-51. doi: 10.1002/jnr.21850.

14.

All JNKs can kill, but nuclear localization is critical for neuronal death.

Björkblom B, Vainio JC, Hongisto V, Herdegen T, Courtney MJ, Coffey ET.

J Biol Chem. 2008 Jul 11;283(28):19704-13. doi: 10.1074/jbc.M707744200. Epub 2008 May 12.

15.

Conventional kinesin holoenzymes are composed of heavy and light chain homodimers.

DeBoer SR, You Y, Szodorai A, Kaminska A, Pigino G, Nwabuisi E, Wang B, Estrada-Hernandez T, Kins S, Brady ST, Morfini G.

Biochemistry. 2008 Apr 15;47(15):4535-43. doi: 10.1021/bi702445j. Epub 2008 Mar 25.

16.

Quantitative and functional analyses of spastin in the nervous system: implications for hereditary spastic paraplegia.

Solowska JM, Morfini G, Falnikar A, Himes BT, Brady ST, Huang D, Baas PW.

J Neurosci. 2008 Feb 27;28(9):2147-57. doi: 10.1523/JNEUROSCI.3159-07.2008.

17.

Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene.

Chen XJ, Levedakou EN, Millen KJ, Wollmann RL, Soliven B, Popko B.

J Neurosci. 2007 Dec 26;27(52):14515-24.

18.

Approaches to kinesin-1 phosphorylation.

Morfini G, Pigino G, Brady ST.

Methods Mol Biol. 2007;392:51-69.

PMID:
17951710
19.

Axonal degeneration in motor neuron disease.

Fischer LR, Glass JD.

Neurodegener Dis. 2007;4(6):431-42. Epub 2007 Oct 9. Review.

PMID:
17934327
20.

Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.

De Vos KJ, Chapman AL, Tennant ME, Manser C, Tudor EL, Lau KF, Brownlees J, Ackerley S, Shaw PJ, McLoughlin DM, Shaw CE, Leigh PN, Miller CCJ, Grierson AJ.

Hum Mol Genet. 2007 Nov 15;16(22):2720-2728. doi: 10.1093/hmg/ddm226. Epub 2007 Aug 28.

Supplemental Content

Support Center