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Items: 1 to 20 of 71


Amyloid deposition is associated with impaired default network function in older persons without dementia.

Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA.

Neuron. 2009 Jul 30;63(2):178-88. doi: 10.1016/j.neuron.2009.07.003.


Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease.

Reiman EM, Chen K, Liu X, Bandy D, Yu M, Lee W, Ayutyanont N, Keppler J, Reeder SA, Langbaum JB, Alexander GE, Klunk WE, Mathis CA, Price JC, Aizenstein HJ, DeKosky ST, Caselli RJ.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6820-5. doi: 10.1073/pnas.0900345106. Epub 2009 Apr 3.


Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease.

Jack CR Jr, Lowe VJ, Weigand SD, Wiste HJ, Senjem ML, Knopman DS, Shiung MM, Gunter JL, Boeve BF, Kemp BJ, Weiner M, Petersen RC; Alzheimer's Disease Neuroimaging Initiative.

Brain. 2009 May;132(Pt 5):1355-65. doi: 10.1093/brain/awp062. Epub 2009 Mar 31.


Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease.

Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, Andrews-Hanna JR, Sperling RA, Johnson KA.

J Neurosci. 2009 Feb 11;29(6):1860-73. doi: 10.1523/JNEUROSCI.5062-08.2009.


Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects.

Mormino EC, Kluth JT, Madison CM, Rabinovici GD, Baker SL, Miller BL, Koeppe RA, Mathis CA, Weiner MW, Jagust WJ; Alzheimer's Disease Neuroimaging Initiative.

Brain. 2009 May;132(Pt 5):1310-23. doi: 10.1093/brain/awn320. Epub 2008 Nov 28.


Frequent amyloid deposition without significant cognitive impairment among the elderly.

Aizenstein HJ, Nebes RD, Saxton JA, Price JC, Mathis CA, Tsopelas ND, Ziolko SK, James JA, Snitz BE, Houck PR, Bi W, Cohen AD, Lopresti BJ, DeKosky ST, Halligan EM, Klunk WE.

Arch Neurol. 2008 Nov;65(11):1509-17. doi: 10.1001/archneur.65.11.1509.


The future of amyloid-beta imaging: a tale of radionuclides and tracer proliferation.

Klunk WE, Mathis CA.

Curr Opin Neurol. 2008 Dec;21(6):683-7. doi: 10.1097/WCO.0b013e3283168e1a. Review.


Imaging amyloid deposition in Lewy body diseases.

Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, Mathis CA, Elmaleh DR, Shoup T, Fischman AJ, Hyman BT, Growdon JH, Johnson KA.

Neurology. 2008 Sep 16;71(12):903-10. doi: 10.1212/01.wnl.0000326146.60732.d6.


Appearance modeling of 11C PiB PET images: characterizing amyloid deposition in Alzheimer's disease, mild cognitive impairment and healthy aging.

Fripp J, Bourgeat P, Acosta O, Raniga P, Modat M, Pike KE, Jones G, O'Keefe G, Masters CL, Ames D, Ellis KA, Maruff P, Currie J, Villemagne VL, Rowe CC, Salvado O, Ourselin S.

Neuroimage. 2008 Nov 15;43(3):430-9. doi: 10.1016/j.neuroimage.2008.07.053. Epub 2008 Aug 12.


The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals.

Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL.

Cereb Cortex. 2009 Mar;19(3):497-510. doi: 10.1093/cercor/bhn113. Epub 2008 Jul 16.


The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis.

Fransson P, Marrelec G.

Neuroimage. 2008 Sep 1;42(3):1178-84. doi: 10.1016/j.neuroimage.2008.05.059. Epub 2008 Jun 12.


Characterizing regional correlation, laterality and symmetry of amyloid deposition in mild cognitive impairment and Alzheimer's disease with Pittsburgh Compound B.

Raji CA, Becker JT, Tsopelas ND, Price JC, Mathis CA, Saxton JA, Lopresti BJ, Hoge JA, Ziolko SK, DeKosky ST, Klunk WE.

J Neurosci Methods. 2008 Jul 30;172(2):277-82. doi: 10.1016/j.jneumeth.2008.05.005. Epub 2008 May 16.


Functional neuroimaging correlates of finger-tapping task variations: an ALE meta-analysis.

Witt ST, Laird AR, Meyerand ME.

Neuroimage. 2008 Aug 1;42(1):343-56. doi: 10.1016/j.neuroimage.2008.04.025. Epub 2008 Apr 16.


Resting-state functional connectivity reflects structural connectivity in the default mode network.

Greicius MD, Supekar K, Menon V, Dougherty RF.

Cereb Cortex. 2009 Jan;19(1):72-8. doi: 10.1093/cercor/bhn059. Epub 2008 Apr 9.


The brain's default network: anatomy, function, and relevance to disease.

Buckner RL, Andrews-Hanna JR, Schacter DL.

Ann N Y Acad Sci. 2008 Mar;1124:1-38. doi: 10.1196/annals.1440.011. Review.


Distinct cortical anatomy linked to subregions of the medial temporal lobe revealed by intrinsic functional connectivity.

Kahn I, Andrews-Hanna JR, Vincent JL, Snyder AZ, Buckner RL.

J Neurophysiol. 2008 Jul;100(1):129-39. doi: 10.1152/jn.00077.2008. Epub 2008 Apr 2.


Impaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease.

Pihlajamäki M, DePeau KM, Blacker D, Sperling RA.

Am J Geriatr Psychiatry. 2008 Apr;16(4):283-92. doi: 10.1097/JGP.0b013e318162a0a9.


Clinical severity of Alzheimer's disease is associated with PIB uptake in PET.

Grimmer T, Henriksen G, Wester HJ, Förstl H, Klunk WE, Mathis CA, Kurz A, Drzezga A.

Neurobiol Aging. 2009 Dec;30(12):1902-9. doi: 10.1016/j.neurobiolaging.2008.01.016. Epub 2008 Mar 17.


Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease.

Villemagne VL, Pike KE, Darby D, Maruff P, Savage G, Ng S, Ackermann U, Cowie TF, Currie J, Chan SG, Jones G, Tochon-Danguy H, O'Keefe G, Masters CL, Rowe CC.

Neuropsychologia. 2008;46(6):1688-97. doi: 10.1016/j.neuropsychologia.2008.02.008. Epub 2008 Feb 14.


Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease.

Ikonomovic MD, Klunk WE, Abrahamson EE, Mathis CA, Price JC, Tsopelas ND, Lopresti BJ, Ziolko S, Bi W, Paljug WR, Debnath ML, Hope CE, Isanski BA, Hamilton RL, DeKosky ST.

Brain. 2008 Jun;131(Pt 6):1630-45. doi: 10.1093/brain/awn016. Epub 2008 Mar 12.

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