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Items: 1 to 20 of 43


Atonal homolog 1 is a tumor suppressor gene.

Bossuyt W, Kazanjian A, De Geest N, Van Kelst S, De Hertogh G, Geboes K, Boivin GP, Luciani J, Fuks F, Chuah M, VandenDriessche T, Marynen P, Cools J, Shroyer NF, Hassan BA.

PLoS Biol. 2009 Feb 24;7(2):e39. doi: 10.1371/journal.pbio.1000039.


Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine.

Shorning BY, Zabkiewicz J, McCarthy A, Pearson HB, Winton DJ, Sansom OJ, Ashworth A, Clarke AR.

PLoS One. 2009;4(1):e4264. doi: 10.1371/journal.pone.0004264. Epub 2009 Jan 23. Erratum in: PLoS One.2009;4(2). doi: 10.1371/annotation/7750701a-2069-4810-820b-b0a02b674a06.


Global gene expression analysis identifies PDEF transcriptional networks regulating cell migration during cancer progression.

Turner DP, Findlay VJ, Kirven AD, Moussa O, Watson DK.

Mol Biol Cell. 2008 Sep;19(9):3745-57. doi: 10.1091/mbc.E08-02-0154. Epub 2008 Jun 25.


Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate.

López-Díaz L, Jain RN, Keeley TM, VanDussen KL, Brunkan CS, Gumucio DL, Samuelson LC.

Dev Biol. 2007 Sep 15;309(2):298-305. Epub 2007 Jul 24.


Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium.

Bastide P, Darido C, Pannequin J, Kist R, Robine S, Marty-Double C, Bibeau F, Scherer G, Joubert D, Hollande F, Blache P, Jay P.

J Cell Biol. 2007 Aug 13;178(4):635-48.


SOX9 is required for the differentiation of paneth cells in the intestinal epithelium.

Mori-Akiyama Y, van den Born M, van Es JH, Hamilton SR, Adams HP, Zhang J, Clevers H, de Crombrugghe B.

Gastroenterology. 2007 Aug;133(2):539-46. Epub 2007 May 21.


Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family.

Hollenhorst PC, Shah AA, Hopkins C, Graves BJ.

Genes Dev. 2007 Aug 1;21(15):1882-94. Epub 2007 Jul 24.


Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis.

Shroyer NF, Helmrath MA, Wang VY, Antalffy B, Henning SJ, Zoghbi HY.

Gastroenterology. 2007 Jun;132(7):2478-88. Epub 2007 Mar 24.


Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression.

Sood AK, Saxena R, Groth J, Desouki MM, Cheewakriangkrai C, Rodabaugh KJ, Kasyapa CS, Geradts J.

Hum Pathol. 2007 Nov;38(11):1628-38. Epub 2007 May 22.


Reduced PDEF expression increases invasion and expression of mesenchymal genes in prostate cancer cells.

Gu X, Zerbini LF, Otu HH, Bhasin M, Yang Q, Joseph MG, Grall F, Onatunde T, Correa RG, Libermann TA.

Cancer Res. 2007 May 1;67(9):4219-26.


Dysregulation of intestinal crypt cell proliferation and villus cell migration in mice lacking Kruppel-like factor 9.

Simmen FA, Xiao R, Velarde MC, Nicholson RD, Bowman MT, Fujii-Kuriyama Y, Oh SP, Simmen RC.

Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1757-69. Epub 2007 Mar 22.


SPDEF regulates goblet cell hyperplasia in the airway epithelium.

Park KS, Korfhagen TR, Bruno MD, Kitzmiller JA, Wan H, Wert SE, Khurana Hershey GK, Chen G, Whitsett JA.

J Clin Invest. 2007 Apr;117(4):978-88. Epub 2007 Mar 8.


Prostate-derived Ets transcription factor (PDEF) downregulates survivin expression and inhibits breast cancer cell growth in vitro and xenograft tumor formation in vivo.

Ghadersohi A, Pan D, Fayazi Z, Hicks DG, Winston JS, Li F.

Breast Cancer Res Treat. 2007 Mar;102(1):19-30. Epub 2006 Aug 8.


Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation.

Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY.

Genes Dev. 2005 Oct 15;19(20):2412-7.


Direct regulation of intestinal fate by Notch.

Stanger BZ, Datar R, Murtaugh LC, Melton DA.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12443-8. Epub 2005 Aug 17.


Notch signals control the fate of immature progenitor cells in the intestine.

Fre S, Huyghe M, Mourikis P, Robine S, Louvard D, Artavanis-Tsakonas S.

Nature. 2005 Jun 16;435(7044):964-8.


Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.

van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, Begthel H, Cozijnsen M, Robine S, Winton DJ, Radtke F, Clevers H.

Nature. 2005 Jun 16;435(7044):959-63.


Analysis of the 2.0 A crystal structure of the protein-DNA complex of the human PDEF Ets domain bound to the prostate specific antigen regulatory site.

Wang Y, Feng L, Said M, Balderman S, Fayazi Z, Liu Y, Ghosh D, Gulick AM.

Biochemistry. 2005 May 17;44(19):7095-106.


Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.

Belteki G, Haigh J, Kabacs N, Haigh K, Sison K, Costantini F, Whitsett J, Quaggin SE, Nagy A.

Nucleic Acids Res. 2005 Mar 22;33(5):e51. Erratum in: Nucleic Acids Res. 2005;33(8):2765.

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