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Multiple functions of MRN in end-joining pathways during isotype class switching.

Dinkelmann M, Spehalski E, Stoneham T, Buis J, Wu Y, Sekiguchi JM, Ferguson DO.

Nat Struct Mol Biol. 2009 Aug;16(8):808-13. doi: 10.1038/nsmb.1639. Epub 2009 Jul 26.


Role of mammalian Mre11 in classical and alternative nonhomologous end joining.

Xie A, Kwok A, Scully R.

Nat Struct Mol Biol. 2009 Aug;16(8):814-8. doi: 10.1038/nsmb.1640. Epub 2009 Jul 26.


Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells.

Rass E, Grabarz A, Plo I, Gautier J, Bertrand P, Lopez BS.

Nat Struct Mol Biol. 2009 Aug;16(8):819-24. doi: 10.1038/nsmb.1641. Epub 2009 Jul 26.


Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

Fekairi S, Scaglione S, Chahwan C, Taylor ER, Tissier A, Coulon S, Dong MQ, Ruse C, Yates JR 3rd, Russell P, Fuchs RP, McGowan CH, Gaillard PH.

Cell. 2009 Jul 10;138(1):78-89. doi: 10.1016/j.cell.2009.06.029.


Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Svendsen JM, Smogorzewska A, Sowa ME, O'Connell BC, Gygi SP, Elledge SJ, Harper JW.

Cell. 2009 Jul 10;138(1):63-77. doi: 10.1016/j.cell.2009.06.030.


Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.

Andersen SL, Bergstralh DT, Kohl KP, LaRocque JR, Moore CB, Sekelsky J.

Mol Cell. 2009 Jul 10;35(1):128-35. doi: 10.1016/j.molcel.2009.06.019.


Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.

Muñoz IM, Hain K, Déclais AC, Gardiner M, Toh GW, Sanchez-Pulido L, Heuckmann JM, Toth R, Macartney T, Eppink B, Kanaar R, Ponting CP, Lilley DM, Rouse J.

Mol Cell. 2009 Jul 10;35(1):116-27. doi: 10.1016/j.molcel.2009.06.020.


XRCC2 and XRCC3 regulate the balance between short- and long-tract gene conversions between sister chromatids.

Nagaraju G, Hartlerode A, Kwok A, Chandramouly G, Scully R.

Mol Cell Biol. 2009 Aug;29(15):4283-94. doi: 10.1128/MCB.01406-08. Epub 2009 May 26.


Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.

Savic V, Yin B, Maas NL, Bredemeyer AL, Carpenter AC, Helmink BA, Yang-Iott KS, Sleckman BP, Bassing CH.

Mol Cell. 2009 May 15;34(3):298-310. doi: 10.1016/j.molcel.2009.04.012.


PALB2 is an integral component of the BRCA complex required for homologous recombination repair.

Sy SM, Huen MS, Chen J.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7155-60. doi: 10.1073/pnas.0811159106. Epub 2009 Apr 15.


Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates.

Deriano L, Stracker TH, Baker A, Petrini JH, Roth DB.

Mol Cell. 2009 Apr 10;34(1):13-25. doi: 10.1016/j.molcel.2009.03.009.


CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

Yun MH, Hiom K.

Nature. 2009 May 21;459(7245):460-3. doi: 10.1038/nature07955. Epub 2009 Apr 8.


PALB2 links BRCA1 and BRCA2 in the DNA-damage response.

Zhang F, Ma J, Wu J, Ye L, Cai H, Xia B, Yu X.

Curr Biol. 2009 Mar 24;19(6):524-9. doi: 10.1016/j.cub.2009.02.018. Epub 2009 Mar 5.


RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.

Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, Ellenberg J, Panier S, Durocher D, Bartek J, Lukas J, Lukas C.

Cell. 2009 Feb 6;136(3):435-46. doi: 10.1016/j.cell.2008.12.041.


The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.

Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, Miller ES, Nakada S, Ylanko J, Olivarius S, Mendez M, Oldreive C, Wildenhain J, Tagliaferro A, Pelletier L, Taubenheim N, Durandy A, Byrd PJ, Stankovic T, Taylor AM, Durocher D.

Cell. 2009 Feb 6;136(3):420-34. doi: 10.1016/j.cell.2008.12.042.


E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks.

Reid LJ, Shakya R, Modi AP, Lokshin M, Cheng JT, Jasin M, Baer R, Ludwig T.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20876-81. doi: 10.1073/pnas.0811203106. Epub 2008 Dec 16.


Identification of Holliday junction resolvases from humans and yeast.

Ip SC, Rass U, Blanco MG, Flynn HR, Skehel JM, West SC.

Nature. 2008 Nov 20;456(7220):357-61. doi: 10.1038/nature07470.


53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.

Dimitrova N, Chen YC, Spector DL, de Lange T.

Nature. 2008 Nov 27;456(7221):524-8. doi: 10.1038/nature07433. Epub 2008 Oct 19.


53BP1 facilitates long-range DNA end-joining during V(D)J recombination.

Difilippantonio S, Gapud E, Wong N, Huang CY, Mahowald G, Chen HT, Kruhlak MJ, Callen E, Livak F, Nussenzweig MC, Sleckman BP, Nussenzweig A.

Nature. 2008 Nov 27;456(7221):529-33. doi: 10.1038/nature07476. Epub 2008 Oct 19.


Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance.

Bohr VA.

Trends Biochem Sci. 2008 Dec;33(12):609-20. doi: 10.1016/j.tibs.2008.09.003. Epub 2008 Oct 14. Review.

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