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Items: 1 to 20 of 69


In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach.

Chavez L, Bais AS, Vingron M, Lehrach H, Adjaye J, Herwig R.

BMC Genomics. 2009 Jul 15;10:314. doi: 10.1186/1471-2164-10-314.


Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells.

Kalaszczynska I, Geng Y, Iino T, Mizuno S, Choi Y, Kondratiuk I, Silver DP, Wolgemuth DJ, Akashi K, Sicinski P.

Cell. 2009 Jul 23;138(2):352-65. doi: 10.1016/j.cell.2009.04.062. Epub 2009 Jul 9.


MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells.

Sengupta S, Nie J, Wagner RJ, Yang C, Stewart R, Thomson JA.

Stem Cells. 2009 Jul;27(7):1524-8. doi: 10.1002/stem.84.


Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?

Gunaratne PH.

Curr Stem Cell Res Ther. 2009 Sep;4(3):168-77. Review.


Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine.

Knoepfler PS.

Stem Cells. 2009 May;27(5):1050-6. doi: 10.1002/stem.37. Review.


Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells.

Filipczyk AA, Laslett AL, Mummery C, Pera MF.

Stem Cell Res. 2007 Oct;1(1):45-60. doi: 10.1016/j.scr.2007.09.002. Epub 2007 Sep 17.


Patient-specific pluripotent stem cells: promises and challenges.

Müller R, Lengerke C.

Nat Rev Endocrinol. 2009 Apr;5(4):195-203. doi: 10.1038/nrendo.2009.18. Review.


A fresh look at iPS cells.

Yamanaka S.

Cell. 2009 Apr 3;137(1):13-7. doi: 10.1016/j.cell.2009.03.034.


CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P.

Mitra P, Ghule PN, van der Deen M, Medina R, Xie RL, Holmes WF, Ye X, Nakayama KI, Harper JW, Stein JL, Stein GS, van Wijnen AJ.

J Cell Physiol. 2009 May;219(2):438-48. doi: 10.1002/jcp.21687.


Tailoring to RB: tumour suppressor status and therapeutic response.

Knudsen ES, Knudsen KE.

Nat Rev Cancer. 2008 Sep;8(9):714-24. doi: 10.1038/nrc2401. Review.


A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A.

Zhang X, Neganova I, Przyborski S, Yang C, Cooke M, Atkinson SP, Anyfantis G, Fenyk S, Keith WN, Hoare SF, Hughes O, Strachan T, Stojkovic M, Hinds PW, Armstrong L, Lako M.

J Cell Biol. 2009 Jan 12;184(1):67-82. doi: 10.1083/jcb.200801009.


Reprogramming of somatic cell identity.

Hanna J, Carey BW, Jaenisch R.

Cold Spring Harb Symp Quant Biol. 2008;73:147-55. doi: 10.1101/sqb.2008.73.025. Epub 2008 Nov 6. Review.


Two supporting factors greatly improve the efficiency of human iPSC generation.

Zhao Y, Yin X, Qin H, Zhu F, Liu H, Yang W, Zhang Q, Xiang C, Hou P, Song Z, Liu Y, Yong J, Zhang P, Cai J, Liu M, Li H, Li Y, Qu X, Cui K, Zhang W, Xiang T, Wu Y, Zhao Y, Liu C, Yu C, Yuan K, Lou J, Ding M, Deng H.

Cell Stem Cell. 2008 Nov 6;3(5):475-9. doi: 10.1016/j.stem.2008.10.002. No abstract available.


Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation.

Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R.

Nat Genet. 2008 Dec;40(12):1478-83. doi: 10.1038/ng.250. Epub 2008 Nov 2.


Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells.

Neganova I, Zhang X, Atkinson S, Lako M.

Oncogene. 2009 Jan 8;28(1):20-30. doi: 10.1038/onc.2008.358. Epub 2008 Sep 22.


The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system.

Macleod KF.

Nat Rev Cancer. 2008 Oct;8(10):769-81. doi: 10.1038/nrc2504. Epub 2008 Sep 18. Review.


Human embryonic stem cell registries: value, challenges and opportunities.

Luong MX, Smith KP, Stein GS.

J Cell Biochem. 2008 Oct 15;105(3):625-32. doi: 10.1002/jcb.21872. Review.


Regulatory networks define phenotypic classes of human stem cell lines.

Müller FJ, Laurent LC, Kostka D, Ulitsky I, Williams R, Lu C, Park IH, Rao MS, Shamir R, Schwartz PH, Schmidt NO, Loring JF.

Nature. 2008 Sep 18;455(7211):401-5. doi: 10.1038/nature07213. Epub 2008 Aug 24.


Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells.

Card DA, Hebbar PB, Li L, Trotter KW, Komatsu Y, Mishina Y, Archer TK.

Mol Cell Biol. 2008 Oct;28(20):6426-38. doi: 10.1128/MCB.00359-08. Epub 2008 Aug 18.


Pluripotent stem cell lines.

Yu J, Thomson JA.

Genes Dev. 2008 Aug 1;22(15):1987-97. doi: 10.1101/gad.1689808. Review.

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