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Items: 1 to 20 of 41

1.

T-bet is essential for encephalitogenicity of both Th1 and Th17 cells.

Yang Y, Weiner J, Liu Y, Smith AJ, Huss DJ, Winger R, Peng H, Cravens PD, Racke MK, Lovett-Racke AE.

J Exp Med. 2009 Jul 6;206(7):1549-64. doi: 10.1084/jem.20082584. Epub 2009 Jun 22.

2.

C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

Reboldi A, Coisne C, Baumjohann D, Benvenuto F, Bottinelli D, Lira S, Uccelli A, Lanzavecchia A, Engelhardt B, Sallusto F.

Nat Immunol. 2009 May;10(5):514-23. doi: 10.1038/ni.1716. Epub 2009 Mar 22.

PMID:
19305396
3.

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways.

Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK.

Genes Dev. 2009 Mar 15;23(6):681-93. doi: 10.1101/gad.1773109.

4.

IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype.

Huber M, Brüstle A, Reinhard K, Guralnik A, Walter G, Mahiny A, von Löw E, Lohoff M.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20846-51. doi: 10.1073/pnas.0809077106. Epub 2008 Dec 16.

5.

The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.

Hermann-Kleiter N, Gruber T, Lutz-Nicoladoni C, Thuille N, Fresser F, Labi V, Schiefermeier N, Warnecke M, Huber L, Villunger A, Eichele G, Kaminski S, Baier G.

Immunity. 2008 Aug 15;29(2):205-16. doi: 10.1016/j.immuni.2008.06.008.

6.

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells.

Lochner M, Peduto L, Cherrier M, Sawa S, Langa F, Varona R, Riethmacher D, Si-Tahar M, Di Santo JP, Eberl G.

J Exp Med. 2008 Jun 9;205(6):1381-93. doi: 10.1084/jem.20080034. Epub 2008 May 26.

7.

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells.

Yang L, Anderson DE, Baecher-Allan C, Hastings WD, Bettelli E, Oukka M, Kuchroo VK, Hafler DA.

Nature. 2008 Jul 17;454(7202):350-2. doi: 10.1038/nature07021. Epub 2008 May 11.

8.

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat.

Manel N, Unutmaz D, Littman DR.

Nat Immunol. 2008 Jun;9(6):641-9. doi: 10.1038/ni.1610. Epub 2008 May 4.

9.

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function.

Zhou L, Lopes JE, Chong MM, Ivanov II, Min R, Victora GD, Shen Y, Du J, Rubtsov YP, Rudensky AY, Ziegler SF, Littman DR.

Nature. 2008 May 8;453(7192):236-40. doi: 10.1038/nature06878. Epub 2008 Mar 26.

10.

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.

Quintana FJ, Basso AS, Iglesias AH, Korn T, Farez MF, Bettelli E, Caccamo M, Oukka M, Weiner HL.

Nature. 2008 May 1;453(7191):65-71. doi: 10.1038/nature06880. Epub 2008 Mar 23.

PMID:
18362915
11.

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins.

Veldhoen M, Hirota K, Westendorf AM, Buer J, Dumoutier L, Renauld JC, Stockinger B.

Nature. 2008 May 1;453(7191):106-9. doi: 10.1038/nature06881. Epub 2008 Mar 23.

PMID:
18362914
12.

Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis.

Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM, Fugger L.

Am J Pathol. 2008 Jan;172(1):146-55. Epub 2007 Dec 21.

13.

Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms.

Straus DS, Glass CK.

Trends Immunol. 2007 Dec;28(12):551-8. Epub 2007 Nov 5. Review.

PMID:
17981503
14.

Th17: the third member of the effector T cell trilogy.

Bettelli E, Korn T, Kuchroo VK.

Curr Opin Immunol. 2007 Dec;19(6):652-7. Epub 2007 Sep 4. Review.

15.

PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism.

Szatmari I, Töröcsik D, Agostini M, Nagy T, Gurnell M, Barta E, Chatterjee K, Nagy L.

Blood. 2007 Nov 1;110(9):3271-80. Epub 2007 Jul 30.

16.

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells.

Nurieva R, Yang XO, Martinez G, Zhang Y, Panopoulos AD, Ma L, Schluns K, Tian Q, Watowich SS, Jetten AM, Dong C.

Nature. 2007 Jul 26;448(7152):480-3. Epub 2007 Jun 20.

PMID:
17581589
17.

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid.

Mucida D, Park Y, Kim G, Turovskaya O, Scott I, Kronenberg M, Cheroutre H.

Science. 2007 Jul 13;317(5835):256-60. Epub 2007 Jun 14.

18.

Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy.

Klotz L, Dani I, Edenhofer F, Nolden L, Evert B, Paul B, Kolanus W, Klockgether T, Knolle P, Diehl L.

J Immunol. 2007 Feb 15;178(4):2122-31.

19.

Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity.

Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L.

J Exp Med. 2007 Feb 19;204(2):321-30. Epub 2007 Jan 29. Erratum in: J Exp Med. 2018 May 17;:.

20.

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR.

Cell. 2006 Sep 22;126(6):1121-33.

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